Publikationen AG Xiang


Hoffmann A, Ettle B, Bruno A, Kulinich A, Hoffmann AC, von Wittgenstein J, Winkler J, Xiang W, Schlachetzki JC
Alpha-synuclein activates BV2 microglia dependent on its aggregation state.
Biochem Biophys Res Commun. 2016;479(4): 881-886

Lee JH, Schierer S, Blume K, Dindorf J, Wittki S, Xiang W, Ostalecki C, Koliha N, Wild S, Schuler G, Fackler OT, Saksela K, Harrer T, Baur AS
HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection.
EBioMedicine. 2016;6: 103-13

Sommer A, Fadler T, Dorfmeister E, Hoffmann AC, Xiang W, Winner B, Prots I
Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model.
J Neuroinflammation. 2016;13(1): 174

Chen YJ, Xiang W, Klucken J, Vollmer F
Tracking micro-optical resonances for identifying and sensing novel procaspase-3 protein marker released from cell cultures in response to toxins.
Nanotechnology. 2016;27(16): 164001


Xiang W, Menges S, Schlachetzki JC, Meixner H, Hoffmann AC, Schlötzer-Schrehardt U, Becker CM, Winkler J, Klucken J
Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity.
Mol Neurodegener. 2015;10: 8

Schreglmann SR, Regensburger M, Rockenstein E, Masliah E, Xiang W, Winkler J, Winner B
The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.
PLoS ONE. 2015;10(5): e0126261

Eckstein M, Zimmermann R, Roth T, Hauck-Dlimi B, Strasser EF, Xiang W
The effects of an overnight holding of whole blood at room temperature on haemoglobin modification and in vitro markers of red blood cell aging.
Vox Sang. 2015;108(4): 359-67


Poehler AM, Xiang W, Spitzer P, May VE, Meixner H, Rockenstein E, Chutna O, Outeiro TF, Winkler J, Masliah E, Klucken J
Autophagy modulates SNCA/?-synuclein release, thereby generating a hostile microenvironment.
Autophagy. 2014;10(12): 2171-92

Eckstein FM, Xiang W, Weiss DR, Zimmermann R, Strasser EF
The influence of pre-analytical conditions on platelet-derived microparticles.
Clin Lab. 2014;60(5): 707-16

Ettle B, Reiprich S, Deusser J, Schlachetzki JC, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.
Mol Cell Neurosci. 2014;62: 68-78

Tian C, Liu D, Xiang W, Kretzschmar HA, Sun QL, Gao C, Xu Y, Wang H, Fan XY, Meng G, Li W, Dong XP
Analyses of the similarity and difference of global gene expression profiles in cortex regions of three neurodegenerative diseases: sporadic Creutzfeldt-Jakob disease (sCJD), fatal familial insomnia (FFI), and Alzheimer’s disease (AD).
Mol Neurobiol. 2014;50(2): 473-81


Xiang W, Weisbach V, Sticht H, Seebahn A, Bussmann J, Zimmermann R, Becker CM
Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes.
Arch Biochem Biophys. 2013;529(1): 34-44

Miranda HugoVicent, Xiang Wei, de Oliveira RitaM, Simoes Tania, Pimentel Jose, Klucken Jochen, Penque Deborah, Outeiro TiagoF
Heat-mediated enrichment of -synuclein from cells and tissue for assessing post-translational modifications
J Neurochem. 2013;126(5): 673-684

Xiang W, Schlachetzki JC, Helling S, Bussmann JC, Berlinghof M, Schäffer TE, Marcus K, Winkler J, Klucken J, Becker CM
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity.
Mol Cell Neurosci. 2013;54: 71-83

Tian C, Liu D, Sun QL, Chen C, Xu Y, Wang H, Xiang W, Kretzschmar HA, Li W, Chen C, Shi Q, Gao C, Zhang J, Zhang BY, Han J, Dong XP
Comparative analysis of gene expression profiles between cortex and thalamus in Chinese fatal familial insomnia patients.
Mol Neurobiol. 2013;48(1): 36-48


Guo D, Xiang W, Seebahn A, Becker CM, Strauss O
Modulation of TTX-sensitive voltage-dependent Na+ channels by ?-bungarotoxin in rat cerebellar neurons.
BMC Neurosci. 2012;13: 36


Tang Y, Xiang W, Terry L, Kretzschmar HA, Windl O
Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathy.
PLoS ONE. 2010;5(12): e14207


Tang Y, Xiang W, Hawkins SA, Kretzschmar HA, Windl O
Transcriptional changes in the brains of cattle orally infected with the bovine spongiform encephalopathy agent precede detection of infectivity.
J Virol. 2009;83(18): 9464-73
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