Publikationen

Publikationen AG Xiang

Minakaki G., Canneva F., Chevessier F., Bode F., Menges S., Timotius I., Kalinichenko L., Meixner H., Müller CP., Eskofier B., Casadei N., Riess O., Schröder R., Winkler J., Xiang W., von Hörsten S., Klucken J.:
Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy
In: Behavioural Brain Research 363 (2019), S. 199-215
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2018.11.035
URL: https://www.sciencedirect.com/science/article/pii/S016643281830754X
Grötsch B., Lux A., Rombouts Y., Hoffmann A., Andreev D., Nimmerjahn F., Xiang W., Scherer HU., Schett G., Bozec A.:
Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss
In: Journal of Bone and Mineral Research (2019)
ISSN: 0884-0431
DOI: 10.1002/jbmr.3705
Hoffmann AC., Minakaki G., Menges S., Salvi R., Savitskiy S., Kazman A., Miranda HV., Mielenz D., Klucken J., Winkler J., Xiang W.:
Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose
In: Scientific Reports 9 (2019)
ISSN: 2045-2322
DOI: 10.1038/s41598-018-35811-8

Prots I., Grosch J., Brazdis RM., Simmnacher K., Veber V., Havlicek S., Hannappel C., Krach F., Krumbiegel M., Schuetz O., Reis A., Wrasidlo W., Galasko DR., Groemer TW., Masliah E., Schlötzer-Schrehardt U., Xiang W., Winkler J., Winner B.:
α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies
In: Proceedings of the National Academy of Sciences of the United States of America 115 (2018), S. 7813-7818
ISSN: 0027-8424
DOI: 10.1073/pnas.1713129115
Sommer A., Maxreiter F., Krach F., Fadler T., Grosch J., Maroni M., Graef D., Eberhardt E., Riemenschneider MJ., Yeo GW., Kohl Z., Xiang W., Gage FH., Winkler J., Prots I., Winner B.:
Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease
In: Cell Stem Cell 23 (2018), S. 123-+
ISSN: 1934-5909
DOI: 10.1016/j.stem.2018.06.015

Minakaki G., Menges S., Kittel A., Emmanouilidou E., Schäffner I., Barkovits K., Bergmann A., Rockenstein E., Adame A., Marxreiter F., Mollenhauer B., Galasko D., Buzás EI., Schlötzer-Schrehardt U., Marcus K., Xiang W., Lie DC., Vekrellis K., Masliah E., Winkler J., Klucken J.:
Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype
In: Autophagy (2017), S. 1-61
ISSN: 1554-8627
DOI: 10.1080/15548627.2017.1395992
Regensburger M., Schreglmann SR., Stoll S., Rockenstein E., Loskarn S., Xiang W., Masliah E., Winner B.:
Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice
In: Brain Structure & Function (2017)
ISSN: 1863-2653
DOI: 10.1007/s00429-017-1561-5

Chen YJ., Xiang W., Klucken J., Vollmer F., Klucken J.:
Tracking micro-optical resonances for identifying and sensing novel procaspase-3 protein marker released from cell cultures in response to toxins
In: Nanotechnology 27 (2016), S. 164001
ISSN: 0957-4484
DOI: 10.1088/0957-4484/27/16/164001
Hoffmann A., Ettle B., Bruno A., Kulinich A., Hoffmann AC., von Wittgenstein J., Winkler J., Xiang W., Schlachetzki J.:
Alpha-synuclein activates BV2 microglia dependent on its aggregation state
In: Biochemical and Biophysical Research Communications 479 (2016), S. 881-886
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2016.09.109
Lee JH., Schierer S., Blume K., Dindorf J., Wittki S., Xiang W., Ostalecki C., Koliha N., Wild S., Schuler G., Fackler OT., Saksela K., Harrer T., Baur A.:
HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection
In: EBioMedicine 6 (2016), S. 103-13
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2016.03.004
Sommer A., Fadler T., Dorfmeister E., Hoffmann AC., Xiang W., Winner B., Prots I.:
Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model
In: Journal of Neuroinflammation 13 (2016), S. 174
ISSN: 1742-2094
DOI: 10.1186/s12974-016-0632-5

Eckstein M., Zimmermann R., Roth T., Hauck-Dlimi B., Strasser EF., Xiang W.:
The effects of an overnight holding of whole blood at room temperature on haemoglobin modification and in vitro markers of red blood cell aging
In: Vox Sanguinis 108 (2015), S. 359-67
ISSN: 0042-9007
DOI: 10.1111/vox.12235
Schreglmann SR., Regensburger M., Rockenstein E., Masliah E., Xiang W., Winkler J., Winner B.:
The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice
In: PLoS ONE 10 (2015), S. e0126261
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0126261
Xiang W., Menges S., Schlachetzki J., Meixner H., Hoffmann AC., Schlötzer-Schrehardt U., Becker CM., Winkler J., Klucken J., Klucken J.:
Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity
In: Molecular Neurodegeneration 10 (2015), S. 8
ISSN: 1750-1326
DOI: 10.1186/s13024-015-0004-0

Eckstein F., Xiang W., Weiss DR., Zimmermann R., Strasser EF.:
The influence of pre-analytical conditions on platelet-derived microparticles
In: Clinical Laboratory 60 (2014), S. 707-16
ISSN: 1433-6510
Ettle B., Reiprich S., Deußer J., Schlachetzki J., Xiang W., Prots I., Masliah E., Winner B., Wegner M., Winkler J.:
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells
In: Molecular and Cellular Neuroscience 62 (2014), S. 68-78
ISSN: 1044-7431
DOI: 10.1016/j.mcn.2014.06.012
Pöhler AM., Xiang W., Spitzer P., May VEL., Meixner H., Rockenstein E., Chutna O., Outeiro TF., Winkler J., Masliah E., Klucken J., Klucken J.:
Autophagy modulates SNCA/?-synuclein release, thereby generating a hostile microenvironment
In: Autophagy 10 (2014), S. 2171-92
ISSN: 1554-8627
DOI: 10.4161/auto.36436
Tian C., Liu D., Xiang W., Kretzschmar HA., Sun QL., Gao C., Xu Y., Wang H., Fan XY., Meng G., Li W., Dong XP.:
Analyses of the similarity and difference of global gene expression profiles in cortex regions of three neurodegenerative diseases: sporadic Creutzfeldt-Jakob disease (sCJD), fatal familial insomnia (FFI), and Alzheimer's disease (AD)
In: Molecular Neurobiology 50 (2014), S. 473-81
ISSN: 0893-7648
DOI: 10.1007/s12035-014-8758-x

Tian C., Liu D., Sun QL., Chen C., Xu Y., Wang H., Xiang W., Kretzschmar HA., Li W., Chen C., Shi Q., Gao C., Zhang J., Zhang BY., Han J., Dong XP.:
Comparative analysis of gene expression profiles between cortex and thalamus in Chinese fatal familial insomnia patients
In: Molecular Neurobiology 48 (2013), S. 36-48
ISSN: 0893-7648
DOI: 10.1007/s12035-013-8426-6
Xiang W., Schlachetzki J., Helling S., Bussmann JC., Berlinghof M., Schäffer T., Marcus K., Winkler J., Klucken J., Becker CM., Klucken J.:
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
In: Molecular and Cellular Neuroscience 54 (2013), S. 71-83
ISSN: 1044-7431
DOI: 10.1016/j.mcn.2013.01.004
Xiang W., Weisbach VG., Sticht H., Seebahn A., Bussmann J., Zimmermann R., Becker CM.:
Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes
In: Archives of Biochemistry and Biophysics 529 (2013), S. 34-44
ISSN: 0003-9861
DOI: 10.1016/j.abb.2012.11.002

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