Publikationen Lehrstuhl 1

Publikationen LS1

2023

Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf S., Besch R., French LE., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
HDAC2 is involved in the regulation of Brn3a in melanocytes and melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2023
Kersten V., Seitz T., Sommer J., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Bone Morphogenetic Protein 13 Has Protumorigenic Effects on Hepatocellular Carcinoma Cells In Vitro.
In: International Journal of Molecular Sciences 24 (2023)
ISSN: 1422-0067
DOI: 10.3390/ijms241311059
Penas C., Arroyo-Berdugo Y., Apraiz A., Rasero J., Muñoa-Hoyos I., Andollo N., Cancho-Galán G., Izu R., Gardeazabal J., Ezkurra PA., Subiran N., Alvarez-Dominguez C., Alonso S., Boßerhoff AK., Asumendi A., Boyano MD.:
Pirin is a prognostic marker of human melanoma that dampens the proliferation of malignant cells by downregulating JARID1B/KDM5B expression
In: Scientific Reports 13 (2023), Art.Nr.: 9561
ISSN: 2045-2322
DOI: 10.1038/s41598-023-36684-2
Sommer J., Ehnis H., Seitz T., Schneider J., Wild A., Moceri S., Buechler C., Bozec A., Weber G., Merkel S., Beckervordersandforth R., Steinkasserer A., Schüle R., Trebicka J., Hartmann A., Boßerhoff AK., von Hörsten S., Dietrich P., Hellerbrand C.:
Four-and-a-Half LIM-Domain Protein 2 (FHL2) Induces Neuropeptide Y (NPY) in Macrophages in Visceral Adipose Tissue and Promotes Diet-Induced Obesity
In: International Journal of Molecular Sciences 24 (2023), Art.Nr.: 14943
ISSN: 1422-0067
DOI: 10.3390/ijms241914943
Sommer J., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Expression of Bone Morphogenetic Protein 14 in Liver Disease and Cancer
In: Livers 3 (2023), S. 282-292
ISSN: 2673-4389
DOI: 10.3390/livers3020019
Stäbler S., Lichtblau A., Gurbiel S., Schubert T., Riechers A., Rottensteiner-Brandl U., Boßerhoff AK.:
MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy
In: Cells 12 (2023), Art.Nr.: 229
ISSN: 2073-4409
DOI: 10.3390/cells12020229
Stüfchen I., Beyer F., Stäbler S., Fischer S., Kappelmann M., Beckervordersandforth R., Boßerhoff AK.:
Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
In: iScience 26 (2023), Art.Nr.: 106919
ISSN: 2589-0042
DOI: 10.1016/j.isci.2023.106919
Stüfchen I., Beyer F., Stäbler S., Fischer S., Kappelmann-Fenzl M., Beckervordersandforth-Bonk R., Boßerhoff AK.:
Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
In: iScience 26 (2023), S. 106919
ISSN: 2589-0042
DOI: 10.1016/j.isci.2023.106919
Zimmermann T., Stäbler S., Taudte RV., Ünüvar S., Groesch S., Arndt S., Karrer S., Fromm M., Boßerhoff AK.:
Cold Atmospheric Plasma Triggers Apoptosis via the Unfolded Protein Response in Melanoma Cells
In: Cancers 15 (2023), Art.Nr.: 1064
ISSN: 2072-6694
DOI: 10.3390/cancers15041064

2022

Arndt S., Unger P., Boßerhoff AK., Berneburg M., Karrer S.:
The anti-fibrotic effect of cold atmospheric plasma on localized scleroderma in vitro and in vivo
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2022
DOI: 10.3390/biomedicines9111545
Böhme-Schäfer I., Lörentz S., Boßerhoff AK.:
Role of Amino Acid Transporter SNAT1/SLC38A1 in Human Melanoma
In: Cancers 14 (2022), Art.Nr.: 2151
ISSN: 2072-6694
DOI: 10.3390/cancers14092151
Chiheb C., Böhme-Schäfer I., Boßerhoff AK.:
Extracellular acidosis leads to the formation of a senescence-like subpopulation in malignant melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Ertekin Ö., Monavari M., Krüger R., Fuentes Chandia MA., Parma B., Letort G., Tripal P., Boccaccini AR., Boßerhoff AK., Ceppi P., Kappelmann-Fenzl M., Leal-Egaña A.:
3D hydrogel-based microcapsules as an in vitro model to study tumorigenicity, cell migration and drug resistance.
In: Acta Biomaterialia (2022)
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2022.02.010
Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf SA., Besch R., French LE., Matthies AO., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma
In: International Journal of Molecular Sciences 23 (2022), Art.Nr.: 849
ISSN: 1422-0067
DOI: 10.3390/ijms23020849
Kluge V., Zimmermann T., Pommer M., Kuphal S., Boßerhoff AK.:
Molecular mechanisms of OIS breakdown in the context of melanoma formation
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Linck-Paulus L., Horn A., Matthies AO., Fischer S., Meister G., Sticht H., Kappelmann-Fenzl M., Boßerhoff AK.:
A novel splice variant of Argonaut 2 affects microRNA target genes and cell viability of melanoma cells
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Linck-Paulus L., Kappelmann-Fenzl M., Meister G., Boßerhoff AK.:
An AGO2 variant affects the function of miRNAs and influences the viability of melanoma cells
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2022
Linck-Paulus L., Meißgeier T., Pieger K., Horn A., Matthies AO., Fischer S., Meister G., Sticht H., Kappelmann-Fenzl M., Boßerhoff AK.:
A previously unknown Argonaute 2 variant positively modulates the viability of melanoma cells
In: Cellular and Molecular Life Sciences 79 (2022), Art.Nr.: 475
ISSN: 1420-682X
DOI: 10.1007/s00018-022-04496-8
Lämmerhirt L., Kappelmann-Fenzl M., Fischer S., Pommer M., Zimmermann T., Kluge V., Matthies AO., Kuphal S., Boßerhoff AK.:
Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
In: Cells 11 (2022), Art.Nr.: 2154
ISSN: 2073-4409
DOI: 10.3390/cells11142154
Lämmerhirt L., Pommer M., Zimmermann T., Kluge V., Kuphal S., Boßerhoff AK.:
The Nuclear Envelope Proteins LMNB1 and LBR influence the Chromatin Structure and Senescence Processes in Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Lörentz S., Böhme-Schäfer I., Boßerhoff AK.:
Importance of the Amino Acid Transporter SNAT1/SLC38A1 in malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Meissgeier T., Linck-Paulus L., Boßerhoff AK.:
The splicing factor PHF5A influences the growth and variability of melanoma cells
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Peschl V., Seitz T., Sommer J., Thasler W., Boßerhoff AK., Hellerbrand C.:
Bone morphogenetic protein 13 in hepatic stellate cells and hepatic fibrosis
In: Journal of Cellular Biochemistry (2022)
ISSN: 0730-2312
DOI: 10.1002/jcb.30248
Rachinger N., Mittag N., Böhme-Schäfer I., Xiang W., Kuphal S., Boßerhoff AK.:
Alpha-Synuclein and Its Role in Melanocytes
In: Cells 11 (2022), Art.Nr.: 2087
ISSN: 2073-4409
DOI: 10.3390/cells11132087
Richter M., Loth Y., Weisenstein C., Wigger AK., Schaar D., Boßerhoff AK., Bolivar PH.:
Ultrasensitive marker-free biomolecular THz-detection for tumor-related analytics
In: Frequenz 76 (2022), S. 627-637
ISSN: 0016-1136
DOI: 10.1515/freq-2022-0092
Richter M., Weisenstein C., Wigger AK., Boßerhoff AK., Bolivar PH.:
Design Aspects for Sensitive Metasurface-Based THz Biosensing in Aqueous Solutions
47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz) (Delft)
In: 2022 47TH INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER AND TERAHERTZ WAVES (IRMMW-THZ 2022), NEW YORK: 2022
DOI: 10.1109/IRMMW-THz50927.2022.9896066
Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models
In: Advanced Functional Materials Volume 32 (2022)
ISSN: 1616-301X
DOI: 10.1002/adfm.202107993
Schmidt S., Fischer S., Schmid R., Arkudas A., Kengel-Bach-Weigand A., Kappelmann-Fenzl M., Boßerhoff AK.:
Molecular analysis of tumor dormancy of the malignant 3D printed model of melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Schott M., Kappelmann-Fenz M., Fischer S., Fernandez-Barrena MG., Pineda-Lucena A., Ávila MA., Kuphal S., Boßerhoff AK.:
Impact of CYLD on chromatin structure and histone methylation in malignant melanoma
In: International Journal of Molecular Medicine 49 (2022), Art.Nr.: 66
ISSN: 1107-3756
DOI: 10.3892/ijmm.2022.5122
Seefried F., Haller L., Fukuda S., Thongmao A., Schneider N., Utikal J., Higashiyama S., Boßerhoff AK., Kuphal S.:
Nuclear AREG affects a low-proliferative phenotype and contributes to drug resistance of melanoma
In: International Journal of Cancer (2022)
ISSN: 0020-7136
DOI: 10.1002/ijc.34254
Seitz T., John N., Sommer J., Dietrich P., Thasler WE., Hartmann A., Evert K., Lang SA., Boßerhoff AK., Hellerbrand C.:
Role of Fibroblast Growth Factors in the Crosstalk of Hepatic Stellate Cells and Uveal Melanoma Cells in the Liver Metastatic Niche
In: International Journal of Molecular Sciences 23 (2022), Art.Nr.: 11524
ISSN: 1422-0067
DOI: 10.3390/ijms231911524
Stüfchen I., Beckervordersandforth R., Fischer S., Kappelmann-Fenzl M., Boßerhoff AK., Beyer F.:
Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo
In: Pigment Cell & Melanoma Research (2022)
ISSN: 1755-1471
DOI: 10.1111/pcmr.13061
Söderberg A., Meißgeier T., Boßerhoff AK., Linck-Paulus L.:
MAGOH and MAGOHB Knockdown in Melanoma Cells Decreases Nonsense-Mediated Decay Activity and Promotes Apoptosis via Upregulation of GADD45A
In: Cells 11 (2022), Art.Nr.: 3859
ISSN: 2073-4409
DOI: 10.3390/cells11233859
Weisenstein C., Richter M., Wigger AK., Boßerhoff AK., Bolivar PH.:
Multifrequency Investigation of Single-and Double-Stranded DNA with Scalable Metamaterial-Based THz Biosensors
In: Biosensors 12 (2022), Art.Nr.: 483
ISSN: 2079-6374
DOI: 10.3390/bios12070483
Weisenstein C., Richter M., Wigger AK., Boßerhoff AK., Haring Bolivar P.:
Substrate-integrated microfluidics for sensitive biosensing with complementary THz metamaterials in water
In: Applied Physics Letters 120 (2022)
ISSN: 0003-6951
DOI: 10.1063/5.0076379
Zimmermann T., Pommer M., Kluge V., Chiheb C., Mühlich S., Boßerhoff AK.:
Detection and quantification of cellular senescence in human melanocytes and melanoma cell lines
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2022
Zimmermann T., Pommer M., Kluge V., Chiheb C., Mühlich S., Boßerhoff AK.:
Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
In: Cells 11 (2022), Art.Nr.: 1489
ISSN: 2073-4409
DOI: 10.3390/cells11091489

2021

Arndt S., Fadil F., Dettmer K., Unger P., Boskovic M., Samol C., Boßerhoff AK., Zimmermann JL., Gruber M., Gronwald W., Karrer S.:
Cold atmospheric plasma changes the amino acid composition of solutions and influences the anti‐tumor effect on melanoma cells
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 7886
ISSN: 1422-0067
DOI: 10.3390/ijms22157886
Arndt S., Fadil F., Dettmer K., Unger P., Boskovic M., Samol C., Boßerhoff AK., Zimmermann JL., Gruber M., Gronwald W., Karrer S.:
Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells
In: International Journal of Molecular Sciences 22 (2021)
ISSN: 1422-0067
DOI: 10.3390/ijms22157886
Arndt S., Unger P., Boßerhoff AK., Berneburg M., Karrer S.:
The anti-fibrotic effect of cold atmospheric plasma on localized scleroderma in vitro and in vivo
In: Biomedicines 9 (2021), Art.Nr.: 1545
ISSN: 2227-9059
DOI: 10.3390/biomedicines9111545
Arndt S., Unger P., Schneider C., Boßerhoff AK., Karrer S.:
Cold atmospheric plasma (CAP) for the selective control of tumor cells
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2021
Boßerhoff AK., Kappelmann-Fenzl M.:
Next Generation Sequencing (NGS): What Can Be Sequenced?
In: Kappelmann-Fenzl, Melanie (Hrsg.): Next Generation Sequencing and Data Analysis, Cham, Schweiz: Springer, 2021, S. 1-15 (Learning Materials in Bioscience)
ISBN: 978-3-030-62489-7
DOI: 10.1007/978-3-030-62490-3
Böhme-Schäfer I., Schoenherr R., Eberle J., Boßerhoff AK.:
Membrane Transporters and Channels in Melanoma
In: Reviews of Physiology Biochemistry and Pharmacology 181 (2021), S. 269-374
ISSN: 0303-4240
DOI: 10.1007/112_2020_17
Fritz V., Malek L., Gaza A., Wormser L., Appel M., Kremer A., Thasler WE., Neurath M., Hellerbrand C., Boßerhoff AK., Dietrich P., Siebler J.:
Combined de‐repression of chemoresistance associated mitogen‐activated protein kinase 14 and activating transcription factor 2 by loss of microrna‐622 in hepatocellular carcinoma
In: Cancers 13 (2021), S. 1-14
ISSN: 2072-6694
DOI: 10.3390/cancers13051183
Fuentes-Chandía M., Vierling A., Kappelmann-Fenzl M., Monavari M., Letort G., Höne L., Parma B., Antara SK., Ertekin Ö., Palmisano R., Dong M., Böpple K., Boccaccini AR., Ceppi P., Boßerhoff AK., Leal-Egaña A.:
3D Spheroids Versus 3D Tumor-Like Microcapsules: Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells
In: Advanced Biology 5 (2021), S. e2000349
ISSN: 2701-0198
DOI: 10.1002/adbi.202000349
Gaza A., Fritz V., Malek L., Wormser L., Treiber N., Danner J., Kremer AE., Thasler WE., Siebler J., Meister G., Neurath MF., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11
In: Neoplasia 23 (2021), S. 502-514
ISSN: 1522-8002
DOI: 10.1016/j.neo.2021.04.001
Haller L., Reichelt J., Boßerhoff AK., Kuphal S.:
The Role of NRN1 in the Development and Progression of malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf S., Besch R., French LE., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
Brn3a expression is epigenetically controlled by HDAC2 in melanocytes and melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2021
Herr F., Schmidt S., Böhme I., Boßerhoff AK.:
Analysis of Glucose Concentration in Melanoma cells under physiological and nutrient-deficient Conditions
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Kappelmann-Fenzl M., Schmidt S., Fischer S., Schmid R., Lämmerhirt L., Fischer L., Schrüfer S., Thievessen I., Schubert DW., Matthies AO., Detsch R., Boccaccini AR., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
Molecular changes induced in melanoma by cell culturing in 3D alginate hydrogels
In: Cancers 13 (2021), S. 72-72
ISSN: 2072-6694
DOI: 10.3390/cancers13164111
Kupke LS., Arndt S., Lenzer S., Metz S., Unger P., Zimmermann JL., Boßerhoff AK., Gruber M., Karrer S.:
Cold atmospheric plasma promotes the immunoreactivity of granulocytes in vitro
In: Biomolecules 11 (2021), Art.Nr.: 902
ISSN: 2218-273X
DOI: 10.3390/biom11060902
Kyjacova L., Saup R., Rothley M., Schmaus A., Wagner T., Boßerhoff AK., Garvalov BK., Thiele W., Sleeman JP.:
Quantitative detection of disseminated melanoma cells by trp-1 transcript analysis reveals stochastic distribution of pulmonary metastases
In: Journal of Clinical Medicine 10 (2021), Art.Nr.: 5459
ISSN: 2077-0383
DOI: 10.3390/jcm10225459
Linck-Paulus L., Lämmerhirt L., Voeller D., Meyer K., Engelmann JC., Spang R., Eichner N., Meister G., Kuphal S., Boßerhoff AK.:
Learning from Embryogenesis-A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development
In: Journal of Clinical Medicine 10 (2021)
ISSN: 2077-0383
DOI: 10.3390/jcm10112259
Pommer M., Kuphal S., Boßerhoff AK.:
Amphiregulin Regulates Melanocytic Senescence
In: Cells 10 (2021)
ISSN: 2073-4409
DOI: 10.3390/cells10020326
Rachinger N., Boßerhoff AK., Kuphal S.:
Sox21-transcriptional Regulation in malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Rachinger N., Fischer S., Böhme I., Linck-Paulus L., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK.:
Loss of gene information: Discrepancies between rna sequencing, cdna microarray, and qrt-pcr
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 9349
ISSN: 1422-0067
DOI: 10.3390/ijms22179349
Sasahira T., Kurihara-Shimomura M., Shimomura H., Boßerhoff AK., Kirita T.:
Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO
In: Journal of Cancer Research and Clinical Oncology (2021)
ISSN: 0171-5216
DOI: 10.1007/s00432-021-03568-9
Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models
In: Advanced Functional Materials (2021)
ISSN: 1616-301X
DOI: 10.1002/adfm.202107993
URL: https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202107993
Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models
In: Advanced Functional Materials (2021)
ISSN: 1616-301X
DOI: 10.1002/adfm.202107993
Seitz T., Hackl C., Freese K., Dietrich P., Mahli A., Thasler RM., Thasler WE., Lang SA., Boßerhoff AK., Hellerbrand C.:
Xanthohumol, a prenylated chalcone derived from hops, inhibits growth and metastasis of melanoma cells
In: Cancers 13 (2021), S. 1-12
ISSN: 2072-6694
DOI: 10.3390/cancers13030511
Stabler S., Rottensteiner-Brandl U., Boßerhoff AK.:
The Role of the Transcription Factor AP2e in the Development of malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Weisenstein C., Wigger AK., Richter M., Sczech R., Boßerhoff AK., Bolivar PH.:
THz Detection of Biomolecules in Aqueous Environments-Status and Perspectives for Analysis Under Physiological Conditions and Clinical use
In: Journal of Infrared, Millimeter, and Terahertz Waves (2021)
ISSN: 1866-6892
DOI: 10.1007/s10762-021-00792-9
Zimmermann T., Gebhardt L., Kreiß L., Schneider C., Arndt S., Karrer S., Friedrich O., Fischer MJM., Boßerhoff AK.:
Acidified nitrite contributes to the antitumor effect of cold atmospheric plasma on melanoma cells
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 3757
ISSN: 1422-0067
DOI: 10.3390/ijms22073757

2020

Arnold J., Engelmann JC., Schneider N., Boßerhoff AK., Kuphal S.:
miR-488-5p and its role in melanoma
In: Experimental and Molecular Pathology 112 (2020), Art.Nr.: 104348
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2019.104348
Dietrich P., Wormser L., Fritz V., Seitz T., de Maria M., Schambony A., Kremer A., Günther C., Itzel T., Thasler WE., Teufel A., Trebicka J., Hartmann A., Neurath M., von Hörsten S., Boßerhoff AK., Hellerbrand C.:
Molecular cross-talk between Y5-receptor and neuropeptide Y drives liver cancer
In: Journal of Clinical Investigation 130 (2020), S. 2509-2526
ISSN: 0021-9738
DOI: 10.1172/JCI131919
Koch A., Ebert EV., Seitz T., Dietrich P., Berneburg M., Boßerhoff AK., Hellerbrand C.:
Characterization of glycolysis-related gene expression in malignant melanoma
In: Pathology Research and Practice 216 (2020), Art.Nr.: 152752
ISSN: 0344-0338
DOI: 10.1016/j.prp.2019.152752
Kurihara–Shimomura M., Sasahira T., Shimomura H., Boßerhoff AK., Kirita T.:
Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma
In: International Journal of Oncology 56 (2020), S. 1093-1100
ISSN: 1019-6439
DOI: 10.3892/ijo.2020.4996
Liebig J., Kuphal S., Boßerhoff AK.:
Hurdling senescence: hur breaks braf-induced senescence in melanocytes and supports melanoma growth
In: Cancers 12 (2020), Art.Nr.: 1299
ISSN: 2072-6694
DOI: 10.3390/cancers12051299
Linck-Paulus L., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Dissimilar Appearances Are Deceptive-Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9010114
Penas C., Apraiz A., Muñoa I., Arroyo-Berdugo Y., Rasero J., Ezkurra PA., Velasco V., Subiran N., Boßerhoff AK., Alonso S., Asumendi A., Boyano MD.:
RKIP regulates differentiation-related features in melanocytic cells
In: Cancers 12 (2020), S. 1-22
ISSN: 2072-6694
DOI: 10.3390/cancers12061451
Petzer V., Tymoszuk P., Asshoff M., Carvalho J., Papworth J., Deantonio C., Bayliss L., Wake MS., Seifert M., Brigo N., Valente de Souza L., Hilbe R., Grubwieser P., Demetz E., Dichtl S., Volani C., Berger S., Böhm F., Hoffmann A., Pfeifhofer-Obermair C., von Raffay L., Sopper S., Arndt S., Boßerhoff AK., Kautz L., Perrier P., Nairz M., Wolf D., Weiss G., Germaschewski V., Theurl I.:
A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease
In: Blood 136 (2020), S. 1080-1090
ISSN: 0006-4971
DOI: 10.1182/blood.2019004653
Schmid R., Schmidt S., Hazur J., Detsch R., Maurer E., Boccaccini AR., Hauptstein J., Teßmar J., Blunk T., Schrüfer S., Schubert DW., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
Comparison of hydrogels for the development of well-defined 3d cancer models of breast cancer and melanoma
In: Cancers 12 (2020), S. 1-21
ISSN: 2072-6694
DOI: 10.3390/cancers12082320
Schmidt S., Schmid R., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
3D Bioprinting of Melanoma Cells with commercially available Bio Inks
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2020
Seitz T., Freese K., Dietrich P., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma
In: Scientific Reports 10 (2020), Art.Nr.: 4546
ISSN: 2045-2322
DOI: 10.1038/s41598-020-61510-4
Sommer J., Dorn C., Gaebele E., Bataille F., Freese K., Seitz T., Thasler WE., Buettner R., Weiskirchen R., Boßerhoff AK., Hellerbrand C.:
Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9010248
Weisenstein C., Schaar D., Wigger AK., Schäfer-Eberwein H., Boßerhoff AK., Bolívar PH.:
Ultrasensitive THz biosensor for PCR-free cDNA detection based on frequency selective surfaces
In: Biomedical Optics Express 11 (2020), S. 448-460
ISSN: 2156-7085
DOI: 10.1364/BOE.380818
Zimmermann T., Schneider C., Gebhardt L., Arndt S., Karrer S., Zimmermann JL., Fischer MJM., Boßerhoff AK.:
The molecular Effects of cold atmospheric Plasma on malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2020

2019

Arndt S., Karrer S., Hellerbrand C., Boßerhoff AK.:
Bone Morphogenetic Protein-6 Inhibits Fibrogenesis in Scleroderma Offering Treatment Options for Fibrotic Skin Disease
In: Journal of Investigative Dermatology (2019)
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.02.020
Arnold J., Engelmann JC., Schneider N., Boßerhoff AK., Kuphal S.:
miR-488-5p and its role in melanoma
In: Experimental and Molecular Pathology 112 (2019)
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2019.104348
Braun C., Schneider N., Pei D., Boßerhoff AK., Kuphal S.:
Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma
In: American Journal of Translational Research 11 (2019), S. 4425-+
ISSN: 1943-8141
Böhme I., Boßerhoff AK.:
Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells
In: Pigment Cell & Melanoma Research 33 (2019), S. 41-51
ISSN: 1755-1471
DOI: 10.1111/pcmr.12811
Datz E., Zeman F., Koller M., Szeimies RM., Berneburg M., Landthaler M., Boßerhoff AK., Karrer S.:
Phototherapy-induced elevation of serum level of melanoma inhibitory activity
In: Photodermatology Photoimmunology & Photomedicine 35 (2019), S. 255-260
ISSN: 0905-4383
DOI: 10.1111/phpp.12461
Dietrich P., Gaza A., Wormser L., Fritz V., Hellerbrand C., Boßerhoff AK.:
Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma
In: Neoplasia 21 (2019), S. 257-268
ISSN: 1522-8002
DOI: 10.1016/j.neo.2018.11.011
Dietrich P., Hellerbrand C., Boßerhoff AK.:
The delta subunit of rod-specific photoreceptor cgmp phosphodiesterase (Pde6d) contributes to hepatocellular carcinoma progression
In: Cancers 11 (2019), Art.Nr.: 398
ISSN: 2072-6694
DOI: 10.3390/cancers11030398
Feuerer L., Lamm S., Henz I., Kappelmann-Fenzl M., Haferkamp S., Meierjohann S., Hellerbrand C., Kuphal S., Boßerhoff AK.:
Role of melanoma inhibitory activity in melanocyte senescence
In: Pigment Cell & Melanoma Research (2019)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12801
Freese K., Dietrich P., Boßerhoff AK., Hellerbrand C.:
Variation of different histone deacetylases and the functional effects of HDAC inhibitors in hepatocellular carcinoma
International Liver Congress (Vienna, 10. April 2019 - 14. April 2019)
In: JOURNAL OF HEPATOLOGY, AMSTERDAM: 2019
DOI: 10.1016/s0618-8278(19)30712-1
Freese K., Seitz T., Dietrich P., Lee SM., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Histone deacetylase expressions in hepatocellular carcinoma and functional effects of histone deacetylase inhibitors on liver cancer cells in vitro
In: Cancers 11 (2019), Art.Nr.: 1587
ISSN: 2072-6694
DOI: 10.3390/cancers11101587
Graf SA., Heppt MV., Wessely A., Krebs S., Kammerbauer C., Hornig E., Strieder A., Blum H., Boßerhoff AK., Berking C.:
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion
In: Pigment Cell & Melanoma Research 32 (2019), S. 424-434
ISSN: 1755-1471
DOI: 10.1111/pcmr.12760
Kappelmann-Fenzl M., Gebhard C., Matthies AO., Kuphal S., Rehli M., Boßerhoff AK.:
C-Jun drives melanoma progression in PTEN wild type melanoma cells
In: Cell Death & Disease 10 (2019), Art.Nr.: 584
ISSN: 2041-4889
DOI: 10.1038/s41419-019-1821-9
Kappelmann-Fenzl M., Kuphal S., Krupar R., Schadendorf D., Umansky V., Vardimon L., Hellerbrand C., Boßerhoff AK.:
Complex formation with monomeric α-tubulin and importin 13 fosters c-jun protein stability and is required for c-jun’s nuclear translocation and activity
In: Cancers 11 (2019), Art.Nr.: 1806
ISSN: 2072-6694
DOI: 10.3390/cancers11111806
Linck-Paulus L., Voeller D., Meister G., Boßerhoff AK.:
Post-transcriptional regulation of Argonaute2 in malignant melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2019
Mahli A., Seitz T., Beckroege T., Freese K., Thasler WE., Benkert M., Dietrich P., Weiskirchen R., Boßerhoff AK., Hellerbrand C.:
Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro
In: Cells 8 (2019)
ISSN: 2073-4409
DOI: 10.3390/cells8050457
Schmidt S., Schmid R., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
Tumor Cells Develop Defined Cellular Phenotypes After 3D-Bioprinting in Different Bioinks
In: Cells 8 (2019)
ISSN: 2073-4409
DOI: 10.3390/cells8101295
Schneider C., Gebhardt L., Arndt S., Karrer S., Zimmermann JL., Fischer M., Boßerhoff AK.:
Acidification is an essential process of cold atmospheric plasma and promotes the anti-cancer effect on malignant melanoma cells
In: Cancers 11 (2019), Art.Nr.: 671
ISSN: 2072-6694
DOI: 10.3390/cancers11050671
Stieglitz D., Lamm S., Braig S., Feuerer L., Kuphal S., Dietrich P., Arndt S., Echtenacher B., Hellerbrand C., Karrer S., Boßerhoff AK.:
BMP6-induced modulation of the tumor micro-milieu
In: Oncogene 38 (2019), S. 609-621
ISSN: 0950-9232
DOI: 10.1038/s41388-018-0475-x
Weisenstein C., Schmeck M., Schaar D., Wigger AK., Boßerhoff AK., Bolivar PH.:
Quantification of dsDNA functionalization efficiency in THz biosensors
44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019 (Paris, 1. September 2019 - 6. September 2019)
In: International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019
DOI: 10.1109/IRMMW-THz.2019.8873759
de Jel MM., Schott M., Lamm S., Neuhuber W., Kuphal S., Boßerhoff AK.:
Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model
In: Oncogenesis 8 (2019), Art.Nr.: 56
ISSN: 2157-9024
DOI: 10.1038/s41389-019-0169-4

2018

Böhme I., Boßerhoff AK.:
Extracellular Acidosis leads to the Development of a senescent-like Phenotype and molecular Reprogramming of human Melanoma Cells
Dietrich P., Freese K., Mahli A., Thasler WE., Hellerbrand C., Boßerhoff AK.:
Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option
In: Oncotarget 9 (2018), S. 3605-3618
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23188
Dietrich P., Kuphal S., Spruss T., Hellerbrand C., Boßerhoff AK.:
MicroRNA-622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma
In: Pigment Cell & Melanoma Research (2018)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12698
Kirchberger MC., Schilling B., Haferkamp S., Boßerhoff AK., Schuler G., Heinzerling L.:
Can checkpoint inhibitor therapy improve response to chemotherapy?
In: Journal of Cancer Research and Clinical Oncology 144 (2018), S. 183-185
ISSN: 0171-5216
DOI: 10.1007/s00432-017-2546-8
Kunz M., Loeffler-Wirth H., Dannemann M., Willscher E., Doose G., Kelso J., Kottek T., Nickel B., Hopp L., Landsberg J., Hoffmann S., Tueting T., Zigrino P., Mauch C., Utikal J., Ziemer M., Schulze HJ., Holzel M., Roesch A., Kneitz S., Meierjohann S., Boßerhoff AK., Binder H., Schartl M.:
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas
In: Oncogene 37 (2018), S. 6136-6151
ISSN: 0950-9232
DOI: 10.1038/s41388-018-0385-y
Larribere L., Kuphal S., Sachpekidis C., Hueser L., Boßerhoff AK., Utikal J.:
Targeted Therapy-Resistant Melanoma Cells Acquire Transcriptomic Similarities with Human Melanoblasts
In: Cancers 10 (2018)
ISSN: 2072-6694
DOI: 10.3390/cancers10110451
Liebig J., Boßerhoff AK.:
Importance of the RNA Binding Protein Hu-antigen R in malignant Melanoma
Linck L., Boßerhoff AK.:
SiRNA-Knockdown einer neuen Argonaute2 Spleißvariante verringert die tumorigenen Eigenschaften von Melanomzellen.
28. Deutscher Hautkrebskongress (, 13. September 2018 - 15. September 2018)
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2018
Linck L., Liebig J., Voeller D., Eichner N., Lehmann G., Meister G., Boßerhoff AK.:
MicroRNA-sequencing data analyzing melanoma development and progression
In: Experimental and Molecular Pathology 105 (2018), S. 371-379
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2018.11.001
Mahli A., Koch A., Fresse K., Schiergens T., Thasler WE., Schoenberger C., Bergheim I., Boßerhoff AK., Hellerbrand C.:
Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis
In: Laboratory Investigation 98 (2018), S. 1614-1626
ISSN: 0023-6837
DOI: 10.1038/s41374-018-0112-x
Rottensteiner-Brandl U., Detsch R., Sarker B., Lingens L., Köhn K., Kneser U., Boßerhoff AK., Horch RE., Boccaccini AR., Arkudas A.:
Encapsulation of Rat Bone Marrow Derived Mesenchymal Stem Cells in Alginate Dialdehyde/Gelatin Microbeads with and without Nanoscaled Bioactive Glass for In Vivo Bone Tissue Engineering.
In: Materials 11 (2018)
ISSN: 1996-1944
DOI: 10.3390/ma11101880
Sasahira T., Boßerhoff AK., Kirita T.:
The importance of melanoma inhibitory activity gene family in the tumor progression of oral cancer
In: Pathology International 68 (2018), S. 278-286
ISSN: 1320-5463
DOI: 10.1111/pin.12672
Schneider C., Arndt S., Zimmermann JL., Li Y., Karrer S., Boßerhoff AK.:
Cold atmospheric plasma treatment inhibits growth in colorectal cancer cells
In: Biological Chemistry 400 (2018), S. 111-122
ISSN: 1431-6730
DOI: 10.1515/hsz-2018-0193
Schneider C., Gebhardt L., Arndt S., Karrer S., Zimmermann JL., Fischer M., Boßerhoff AK.:
Cold atmospheric plasma causes a calcium influx in melanoma cells triggering CAP-induced senescence
In: Scientific Reports 8 (2018)
ISSN: 2045-2322
DOI: 10.1038/s41598-018-28443-5
Schott M., de Jel MM., Boßerhoff AK., Kuphal S.:
CYLD - A potential Mediator of tissue-specific Melanoma Metastasis
Schott M., de Jel MM., Engelmann JC., Renner P., Geissler EK., Boßerhoff AK., Kuphal S.:
Selenium-binding protein 1 is down-regulated in malignant melanoma
In: Oncotarget 9 (2018), S. 10445-10456
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23853
Weisenstein C., Schaar D., Schmeck M., Wigger AK., Boßerhoff AK., Bolivar PH.:
Detection of Human Tumor Markers with THz Metamaterials
43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018 (Nagoya, 9. September 2018 - 14. September 2018)
In: International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2018
DOI: 10.1109/IRMMW-THz.2018.8510052

2017

Arndt S., Unger P., Berneburg M., Boßerhoff AK., Karrer S.:
Cold atmospheric plasma (CAP) activates angiogenesis-related molecules in skin keratinocytes, fibroblasts and endothelial cells and improves wound angiogenesis in an autocrine and paracrine mode
In: Journal of Dermatological Science (2017)
ISSN: 0923-1811
DOI: 10.1016/j.jdermsci.2017.11.008
Boßerhoff AK.:
Melanoma development: Molecular biology, genetics and clinical application
Springer International Publishing, 2017
ISBN: 9783319413198
DOI: 10.1007/978-3-319-41319-8
Boßerhoff AK., Schneider N., Ellmann L., Heinzerling L., Kuphal S.:
The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry
In: Oncotarget 8 (2017), S. 1117-1131
ISSN: 1949-2553
DOI: 10.18632/oncotarget.13585
Boßerhoff AK., Schuler G., Heinzerling L., Schilling B., Haferrkamp S., Kirchberger M.:
Can checkpoint inhibitor therapy improve response to chemotherapy?
Boßerhoff AK., Strizzi L.:
Clinicopathologic overview of melanoma
Springer International Publishing, 2017
ISBN: 9783319413198
DOI: 10.1007/978-3-319-41319-8_1
Christoph J., Knell C., Boßerhoff AK., Naschberger E., Stürzl M., Rübner M., Seuß H., Ruh M., Prokosch HU., Sedlmayr B.:
Usability and Suitability of the Omics-Integrating Analysis Platform tranSMART for Translational Research and Education
In: Applied Clinical Informatics 8 (2017), S. 1173-1183
ISSN: 1869-0327
DOI: 10.4338/ACI-2017-05-RA-0085
Dietrich P., Boßerhoff AK.:
Melanoma sponge on pigmentation gene to reduce tumour-suppressive microRNAs
In: Pigment Cell & Melanoma Research (2017)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12660
Dietrich P., Koch A., Fritz V., Hartmann A., Boßerhoff AK., Hellerbrand C.:
Wild type Kirsten rat sarcoma is a novel microRNA-622-regulated therapeutic target for hepatocellular carcinoma and contributes to sorafenib resistance
In: Gut (2017)
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2017-315402
Dietrich P., Kuphal S., Spruss T., Hellerbrand C., Boßerhoff AK.:
Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition
In: Oncogene (2017)
ISSN: 0950-9232
DOI: 10.1038/onc.2017.391
Krupar R., Hautmann MG., Pathak RR., Varier I., Mclaren C., Gaag D., Hellerbrand C., Evert M., Laban S., Idel C., Sandulache V., Perner S., Boßerhoff AK., Sikora AG.:
Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma
In: American Journal of Pathology (2017)
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2017.09.013
Kuphal S., Schneider N., Massoumi R., Hellerbrand C., Boßerhoff AK.:
UVB radiation represses CYLD expression in melanocytes
In: Oncology Letters 14 (2017), S. 7262-7268
ISSN: 1792-1074
DOI: 10.3892/ol.2017.7120
Mahli A., Saugspier M., Koch A., Sommer J., Dietrich P., Lee S., Thasler R., Schulze-Luehrmann J., Lührmann A., Thasler WE., Müller M., Boßerhoff AK., Hellerbrand C.:
ERK activation and autophagy impairment are central mediators of irinotecan-induced steatohepatitis
In: Gut (2017)
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2016-312485
Maisch T., Boßerhoff AK., Unger P., Heider J., Shimizu T., Zimmermann JL., Morfill GE., Landthaler M., Karrer S.:
Investigation of toxicity and mutagenicity of cold atmospheric argon plasma
In: ENVIRON MOL MUTAGEN 58 (2017), S. 172-177
ISSN: 0893-6692
DOI: 10.1002/em.22086
Maurus K., Hufnagel A., Geiger F., Graf S., Berking C., Heinemann A., Paschen A., Kneitz S., Stigloher C., Geissinger E., Otto C., Boßerhoff AK., Schartl M., Meierjohann S.:
The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation
In: Oncogene 36 (2017), S. 5110-5121
ISSN: 0950-9232
DOI: 10.1038/onc.2017.135
Meyer T., Koch A., Ebert EV., Czech B., Mueller M., Boßerhoff AK., Lang SA., Hellerbrand C.:
Effect of melanoma cells on proliferation and migration of activated hepatic stellate cells in vitro
In: Pathology Research and Practice 213 (2017), S. 400-404
ISSN: 0344-0338
DOI: 10.1016/j.prp.2016.12.014
Mione M., Liebig J., Munoz L., Boßerhoff AK.:
MiRNAs in malignant melanoma
Springer International Publishing, 2017
ISBN: 9783319413198
DOI: 10.1007/978-3-319-41319-8_6
Sommer J., Mahli A., Freese K., Schiergens TS., Kuecuekoktay FS., Teufel A., Thasler WE., Mueller M., Boßerhoff AK., Hellerbrand C.:
Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice
In: Oncotarget 8 (2017), S. 13059-13072
ISSN: 1949-2553
DOI: 10.18632/oncotarget.14371
Uslu U., Schliep S., Schliep K., Erdmann M., Koch HU., Parsch H., Rosenheinrich S., Anzengruber D., Boßerhoff AK., Schuler G., Schuler-Thurner B.:
Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells
In: Anticancer Research 37 (2017), S. 5033-5037
ISSN: 0250-7005
DOI: 10.21873/anticanres.11918

2016

Böhme I., Boßerhoff AK.:
Acidic tumor microenvironment in human melanoma
In: Pigment Cell & Melanoma Research 29 (2016), S. 508-23
ISSN: 1755-1471
DOI: 10.1111/pcmr.12495
Dietrich P., Boßerhoff AK.:
DNMT targets MiRacle torching TORCh
In: Pigment Cell & Melanoma Research 29 (2016), S. 399-401
ISSN: 1755-1471
DOI: 10.1111/pcmr.12484
Henrich F., Singer K., Poller K., Bernhardt L., Strobl C., Limm K., Ritter AP., Gottfried E., Voelkl S., Jacobs B., Peter K., Mougiakakos D., Dettmer K., Oefner PJ., Boßerhoff AK., Kreutz MP., Aigner M., Mackensen A.:
Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cells
In: OncoImmunology 5 (2016), S. e1184802
ISSN: 2162-4011
DOI: 10.1080/2162402X.2016.1184802
Limm K., Dettmer K., Reinders J., Oefner PJ., Boßerhoff AK.:
Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma
In: PLoS ONE 11 (2016), S. e0160348
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0160348
Moeckel S., Vollmann-Zwerenz A., Proescholdt M., Brawanski A., Riemenschneider MJ., Bogdahn U., Boßerhoff AK., Spang R., Hau P.:
Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro
In: PLoS ONE 11 (2016), S. e0151312
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0151312
Ott C., Linck L., Kremmer E., Meister G., Boßerhoff AK.:
Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells
In: Oncotarget (2016)
ISSN: 1949-2553
DOI: 10.18632/oncotarget.11410
Reinders Y., Voeller D., Boßerhoff AK., Oefner PJ., Reinders J.:
Testing Suitability of Cell Cultures for SILAC-Experiments Using SWATH-Mass Spectrometry
In: Methods in Molecular Biology 1394 (2016), S. 101-8
ISSN: 1064-3745
DOI: 10.1007/978-1-4939-3341-9_8
Ruedel A., Schott M., Schubert T., Boßerhoff AK.:
Robo3A and Robo3B expression is regulated via alternative promoters and mRNA stability
In: Cancer Cell International 16 (2016), Art.Nr.: 71
ISSN: 1475-2867
DOI: 10.1186/s12935-016-0347-9
Sasahira T., Kirita T., Nishiguchi Y., Kurihara M., Nakashima C., Boßerhoff AK., Kuniyasu H.:
A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma
In: Oncotarget 7 (2016), S. 31137-52
ISSN: 1949-2553
DOI: 10.18632/oncotarget.9082
Sasahira T., Nishiguchi Y., Fujiwara R., Kurihara M., Kirita T., Boßerhoff AK., Kuniyasu H.:
Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression
In: Oncotarget 7 (2016), S. 26751-64
ISSN: 1949-2553
DOI: 10.18632/oncotarget.8495
Schummer P., Kuphal S., Vardimon L., Boßerhoff AK., Kappelmann M.:
Specific c-Jun target genes in malignant melanoma
In: Cancer Biology & Therapy 17 (2016), S. 486-97
ISSN: 1538-4047
DOI: 10.1080/15384047.2016.1156264
Sommer J., Mahli A., Freese K., Thasler W., Kuecuekoktay F., Boßerhoff AK., Mueller M., Hellerbrand C.:
ANALYSIS OF MOLECULAR MECHANISMS OF 5-FLUOROURACIL INDUCED STEATOSIS AND INFLAMMATION IN VITRO AND IN MICE
Voeller D., Linck L., Bruckmann A., Hauptmann J., Deutzmann R., Meister G., Boßerhoff AK.:
Argonaute Family Protein Expression in Normal Tissue and Cancer Entities
In: PLoS ONE 11 (2016), S. e0161165
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0161165
de Jel MM., Schiffner S., Kuphal S., Boßerhoff AK.:
Loss of CYLD promotes melanoma progression

2015

Arndt S., Landthaler M., Zimmermann JL., Unger P., Wacker E., Shimizu T., Li YF., Morfill GE., Boßerhoff AK., Karrer S.:
Effects of Cold Atmospheric Plasma (CAP) on ß-Defensins, Inflammatory Cytokines, and Apoptosis-Related Molecules in Keratinocytes In Vitro and In Vivo
In: PLoS ONE 10 (2015), S. e0120041
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0120041
Arndt S., Wacker E., Dorn C., Koch A., Saugspier M., Thasler WE., Hartmann A., Bosserhoff AK., Hellerbrand C.:
Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease
In: Gut 64 (2015), S. 973-81
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2014-306968
Delic S., Thuy A., Schulze M., Proescholdt MA., Dietrich P., Boßerhoff AK., Riemenschneider MJ.:
Systematic Investigation of CMTM Family Genes Suggests Relevance to Glioblastoma Pathogenesis and CMTM1 and CMTM3 as Priority Targets
In: Genes Chromosomes & Cancer 54 (2015), S. 433-443
ISSN: 1045-2257
DOI: 10.1002/gcc.22255
Dietrich P., Boßerhoff AK.:
Modifying microRNAs--another piece of the melanoma puzzle
In: Pigment Cell & Melanoma Research 28 (2015), S. 488-9
ISSN: 1755-1471
DOI: 10.1111/pcmr.12389
Koch A., Lang SA., Wild PJ., Gantner S., Mahli A., Spanier G., Berneburg M., Mueller M., Boßerhoff AK., Hellerbrand C.:
Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells
In: Oncotarget 6 (2015), S. 32748-60
ISSN: 1949-2553
DOI: 10.18632/oncotarget.4977
Mione M., Boßerhoff AK.:
MicroRNAs in melanocyte and melanoma biology
In: Pigment Cell & Melanoma Research 28 (2015), S. 340-54
ISSN: 1755-1471
DOI: 10.1111/pcmr.12346
Niebler S., Angele P., Kujat R., Boßerhoff AK.:
Hypoxia-Inducible Factor 1 Is an Inductor of Transcription Factor Activating Protein 2 Epsilon Expression during Chondrogenic Differentiation
In: BioMed Research International 2015 (2015), S. 380590
ISSN: 2314-6133
DOI: 10.1155/2015/380590
Niebler S., Schubert T., Hunziker EB., Boßerhoff AK.:
Activating enhancer binding protein 2 epsilon (AP-2?)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development
In: Arthritis Research & Therapy 17 (2015), S. 119
ISSN: 1478-6362
DOI: 10.1186/s13075-015-0648-8
Ruedel A., Dietrich P., Schubert T., Hofmeister S., Hellerbrand C., Boßerhoff AK.:
Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts
In: International Journal of Clinical and Experimental Pathology 8 (2015), S. 4953-62
ISSN: 1936-2625

2014

Bosserhoff AK., Ellmann L., Quast AS., Eberle J., Boyle GM., Kuphal S.:
Loss of T-cadherin (CDH-13) regulates AKT signaling and desensitizes cells to apoptosis in melanoma
In: Molecular Carcinogenesis 53 (2014), S. 635-647
ISSN: 0899-1987
DOI: 10.1002/mc.22018
Bosserhoff AK., Hofmeister S., Ruedel A., Schubert T.:
DCC is expressed in a CD166-positive subpopulation of chondrocytes in human osteoarthritic cartilage and modulates CRE activity
In: International Journal of Clinical and Experimental Pathology 7 (2014), S. 1947-1956
ISSN: 1936-2625
De Jel MM., Engelmann JC., Kunz M., Schiffner S., Kuphal S., Bosserhoff AK.:
Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations
In: Pigment Cell & Melanoma Research 27 (2014), S. 678-680
ISSN: 1755-1471
DOI: 10.1111/pcmr.12244
Graf SA., Busch C., Besch R., Berking C., Bosserhoff AK.:
SOX10 promotes melanoma cell invasion by regulating melanoma inhibitory activity
In: Journal of Investigative Dermatology 134 (2014), S. 2212-2220
ISSN: 0022-202X
DOI: 10.1038/jid.2014.128
Krupar R., Robold K., Gaag D., Spanier G., Kreutz M., Renner K., Hellerbrand C., Hofstaedter F., Bosserhoff AK.:
Immunologic and metabolic characteristics of HPV-negative and HPV-positive head and neck squamous cell carcinomas are strikingly different.
In: Virchows Archiv 465 (2014), S. 299-312
ISSN: 0945-6317
DOI: 10.1007/s00428-014-1630-6
Limm K., Wallner S., Milenkovi VM., Wetzel CH., Bosserhoff AK.:
The metabolite 5′-methylthioadenosine signals through the adenosine receptor A2B in melanoma
In: European Journal of Cancer 50 (2014), S. 2714-2724
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2014.07.005
Maerker DA., Zeschnigk M., Nelles J., Lohmann DR., Worm K., Krupar R., Jaegle H., Bosserhoff AK.:
BAP1 germline mutation in two first grade family members with uveal melanoma
In: British Journal of Ophthalmology 98 (2014), S. 224-227
ISSN: 0007-1161
DOI: 10.1136/bjophthalmol-2013-303814
Moeckel S., Meyer K., Leukel P., Heudorfer F., Seliger C., Stangl C., Bogdahn U., Proescholdt M., Brawanski A., Vollmann-Zwerenz A., Riemenschneider MJ., Spang R., Hau P., Bosserhoff AK.:
Response-predictive gene expression profiling of glioma progenitor cells in vitro
In: PLoS ONE 9 (2014), Art.Nr.: e108632
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0108632
Pannem RR., Dorn C., Ahlqvist K., Hellerbrand C., Massoumi R., Bosserhoff AK.:
CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma
In: Carcinogenesis 35 (2014), S. 461-468
ISSN: 0143-3334
DOI: 10.1093/carcin/bgt335
Riechers A., Bosserhoff AK.:
Melanoma inhibitory activity in melanoma diagnostics and therapy - a small protein is looming large
In: Experimental Dermatology 23 (2014), S. 12-14
ISSN: 0906-6705
DOI: 10.1111/exd.12281
Ruedel A., Stark K., Kaufmann S., Bauer R., Reinders J., Rovensky J., Blazickova S., Oefner PJ., Bosserhoff AK.:
N-cadherin promoter polymorphisms and risk of osteoarthritis
In: The FASEB Journal 28 (2014), S. 683-691
ISSN: 0892-6638
DOI: 10.1096/fj.13-238295
Sasahira T., Kirita T., Yamamoto K., Ueda N., Kurihara M., Matsushima S., Bhawal UK., Bosserhoff AK., Kuniyasu H.:
Transport and Golgi organisation protein 1 is a novel tumour progressive factor in oral squamous cell carcinoma
In: European Journal of Cancer 50 (2014), S. 2142-2151
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2014.05.006
Schiffner S., Braunger BM., De Jel MM., Coupland SE., Tamm ER., Bosserhoff AK.:
Tg(Grm1) transgenic mice: A murine model that mimics spontaneous uveal melanoma in humans?
In: Experimental Eye Research 127 (2014), S. 59-68
ISSN: 0014-4835
DOI: 10.1016/j.exer.2014.07.009
Schmid R., Bosserhoff AK.:
Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice
In: Mechanisms of Development 131 (2014), S. 24-34
ISSN: 0925-4773
DOI: 10.1016/j.mod.2013.11.001
Valletta D., Czech B., Spruss T., Ikenberg K., Wild P., Hartmann A., Weiss TS., Oefner PJ., Mueller M., Hellerbrand C., Bosserhoff AK.:
Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma
In: Carcinogenesis 35 (2014), S. 1407-15
ISSN: 0143-3334
DOI: 10.1093/carcin/bgu054

2013

Arndt S., Unger P., Wacker E., Shimizu T., Heinlin J., Li YF., Thomas HM., Morfill GE., Zimmermann JL., Karrer S., Bosserhoff AK.:
Cold atmospheric plasma (CAP) changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo
In: PLoS ONE 8 (2013), Art.Nr.: e79325
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0079325
Arndt S., Wacker E., Li YF., Shimizu T., Thomas HM., Morfill GE., Karrer S., Zimmermann JL., Bosserhoff AK.:
Cold atmospheric plasma, a new strategy to induce senescence in melanoma cells
In: Experimental Dermatology 22 (2013), S. 284-289
ISSN: 0906-6705
DOI: 10.1111/exd.12127
Braig S., Bosserhoff AK.:
Death inducer-obliterator 1 (Dido1) is a BMP target gene and promotes BMP-induced melanoma progression
In: Oncogene 32 (2013), S. 837-848
ISSN: 0950-9232
DOI: 10.1038/onc.2012.115
Canady J., Arndt S., Karrer S., Bosserhoff AK.:
Increased KGF expression promotes fibroblast activation in a double paracrine manner resulting in cutaneous fibrosis
In: Journal of Investigative Dermatology 133 (2013), S. 647-657
ISSN: 0022-202X
DOI: 10.1038/jid.2012.389
Canady J., Karrer S., Fleck M., Bosserhoff AK.:
Fibrosing connective tissue disorders of the skin: Molecular similarities and distinctions
In: Journal of Dermatological Science 70 (2013), S. 151-158
ISSN: 0923-1811
DOI: 10.1016/j.jdermsci.2013.03.005
Kappelmann M., Kuphal S., Meister G., Vardimon L., Bosserhoff AK.:
MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression
In: Oncogene 32 (2013), S. 2984-2991
ISSN: 0950-9232
DOI: 10.1038/onc.2012.307
Kuphal S., Bosserhoff AK.:
miR networks in melanoma - more to come!
In: Pigment Cell & Melanoma Research 26 (2013), S. 292-293
ISSN: 1755-1471
DOI: 10.1111/pcmr.12073
Kuphal S., Wallner S., Bosserhoff AK.:
Impact of LIF (leukemia inhibitory factor) expression in malignant melanoma
In: Experimental and Molecular Pathology 95 (2013), S. 156-165
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2013.06.012
Kurihara M., Kirita T., Sasahira T., Ohmori H., Matsushima S., Yamamoto K., Kuniyasu H., Bosserhoff AK.:
Protumoral roles of melanoma inhibitory activity 2 in oral squamous cell carcinoma
In: British Journal of Cancer 108 (2013), S. 1460-1469
ISSN: 0007-0920
DOI: 10.1038/bjc.2013.27
Limm K., Ott C., Wallner S., Mueller DW., Oefner P., Hellerbrand C., Bosserhoff AK.:
Deregulation of protein methylation in melanoma
In: European Journal of Cancer 49 (2013), S. 1305-1313
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2012.11.026
Niebler S., Bosserhoff AK.:
The transcription factor activating enhancer-binding protein epsilon (AP-2ε) regulates the core promoter of type II collagen (COL2A1)
In: Febs Journal 280 (2013), S. 1397-1408
ISSN: 1742-464X
DOI: 10.1111/febs.12130
Pornwilard MM., Weiskirchen R., Gassler N., Bosserhoff AK., Becker JS.:
Novel Bioimaging Techniques of Metals by Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Diagnosis Of Fibrotic and Cirrhotic Liver Disorders
In: PLoS ONE 8 (2013), Art.Nr.: e58702
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0058702
Ruede A., Hofmeister S., Bosserhoff AK.:
Development of a model system to analyze chondrogenic differentiation of mesenchymal stem cells
In: International Journal of Clinical and Experimental Pathology 6 (2013), S. 3042-3048
ISSN: 1936-2625
Schmid R., Meyer K., Spang R., Schittek B., Bosserhoff AK.:
Melanoma inhibitory activity promotes melanoma development through activation of YBX1
In: Pigment Cell & Melanoma Research 26 (2013), S. 685-696
ISSN: 1755-1471
DOI: 10.1111/pcmr.12119
Schmid R., Meyer K., Spang R., Schittek B., Bosserhoff AK.:
YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis
In: PLoS ONE 8 (2013), Art.Nr.: e82166
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0082166
Schmidt J., Riechers A., Bosserhoff AK.:
MIA - A new target protein for malignant melanoma therapy
In: Histology and Histopathology 28 (2013), S. 421-426
ISSN: 0213-3911
Seliger C., Leukel P., Moeckel S., Jachnik B., Lottaz C., Kreutz M., Brawanski A., Proescholdt M., Bogdahn U., Vollmann-Zwerenz A., Hau P., Bosserhoff AK.:
Lactate-modulated induction of THBS-1 activates Transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro
In: PLoS ONE 8 (2013), Art.Nr.: e78935
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0078935
Stoeckl S., Bauer RJ., Goettl C., Grifka J., Graessel S., Bosserhoff AK.:
Sox9 modulates cell survival and adipogenic differentiation of multipotent adult rat mesenchymal stem cells
In: Journal of cell science 126 (2013), S. 2890-2902
ISSN: 1477-9137
DOI: 10.1242/jcs.124305
Voeller D., Reinders J., Meister G., Bosserhoff AK.:
Strong reduction of AGO2 expression in melanoma and cellular consequences
In: British Journal of Cancer 109 (2013), S. 3116-3124
ISSN: 0007-0920
DOI: 10.1038/bjc.2013.646

2012

Eckey M., Kuphal S., Straub T., Ruemmele P., Kremmer E., Bosserhoff AK., Becker PB.:
Nucleosome Remodeler SNF2L Suppresses Cell Proliferation and Migration and Attenuates Wnt Signaling
In: Molecular and Cellular Biology 32 (2012), S. 2359-2371
ISSN: 0270-7306
DOI: 10.1128/MCB.06619-11
Ellmann L., Joshi MB., Resink TJ., Bosserhoff AK., Kuphal S.:
BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells
In: Laboratory Investigation 92 (2012), S. 1788-1800
ISSN: 0023-6837
DOI: 10.1038/labinvest.2012.140
Kuphal S., Bosserhoff AK.:
E-cadherin cell-cell communication in melanogenesis and during development of malignant melanoma
In: Archives of Biochemistry and Biophysics 524 (2012), S. 43-47
ISSN: 0003-9861
DOI: 10.1016/j.abb.2011.10.020
Mueller DW., Bosserhoff AK.:
MicroRNAS as biomarkers and therapeutic targets in melanoma
Springer New York, 2012
ISBN: 9781607614333
DOI: 10.1007/978-1-60761-433-3_10
Riechers A., Bosserhoff AK.:
Brief communication: Pitfalls in immunohistochemistry - A recent example
In: International Journal of Clinical and Experimental Pathology 5 (2012), S. 137-139
ISSN: 1936-2625
Schmidt J., Riechers A., Stoll R., Amann T., Fink F., Spruss T., Gronwald W., Koenig B., Hellerbrand C., Bosserhoff AK.:
Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition
In: PLoS ONE 7 (2012), Art.Nr.: e37941
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0037941
Schubert T., Denk AE., Ruedel A., Kaufmann S., Hustert E., Bastone P., Bosserhoff AK.:
Fragments of SLIT3 inhibit cellular migration
In: International Journal of Molecular Medicine 30 (2012), S. 1133-1137
ISSN: 1107-3756
DOI: 10.3892/ijmm.2012.1098
Schubert TEO., Bosserhoff AK., Peyssonnaux C., Echtenacher B., Knutson M., Hofstaedter F., Maennel DN.:
Hypoferraemia during the early inflammatory response is dependent on tumour necrosis factor activity in a murine model of protracted peritonitis
In: Molecular Medicine Reports 6 (2012), S. 838-842
ISSN: 1791-2997
DOI: 10.3892/mmr.2012.1004
Spangler B., Kappelmann M., Schittek B., Meierjohann S., Vardimon L., Bosserhoff AK., Kuphal S.:
ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanoma
In: International Journal of Cancer 130 (2012), S. 2801-2811
ISSN: 0020-7136
DOI: 10.1002/ijc.26277
Voeller D., Bosserhoff AK.:
MicroRNAs and signaling, complex interaction by feedback loops
In: Pigment Cell & Melanoma Research 25 (2012), S. 128-130
ISSN: 1755-1471
DOI: 10.1111/j.1755-148X.2012.00980.x
Yang PT., Anastas JN., Toroni RA., Shinohara MM., Goodson JM., Bosserhoff AK., Chien AJ., Moon RT.:
WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis
In: Embo Molecular Medicine 4 (2012), S. 1294-1307
ISSN: 1757-4676
DOI: 10.1002/emmm.201201486

2009

Wehder L., Arndt S., Murzik U., Kob R., Von Eggeling F., Melle C., Bosserhoff AK.:
Annexin A5 is involved in migration and invasion of oral carcinoma
In: Cell Cycle 8 (2009), S. 1552-1558
ISSN: 1538-4101

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