Publikationen Lehrstuhl 1

Publikationen LS1

2022

Arndt S., Unger P., Boßerhoff AK., Berneburg M., Karrer S.:
The anti-fibrotic effect of cold atmospheric plasma on localized scleroderma in vitro and in vivo
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2022
DOI: 10.3390/biomedicines9111545
Böhme-Schäfer I., Lörentz S., Boßerhoff AK.:
Role of Amino Acid Transporter SNAT1/SLC38A1 in Human Melanoma
In: Cancers 14 (2022), Art.Nr.: 2151
ISSN: 2072-6694
DOI: 10.3390/cancers14092151
Ertekin Ö., Monavari M., Krüger R., Fuentes Chandia MA., Parma B., Letort G., Tripal P., Boccaccini AR., Boßerhoff AK., Ceppi P., Kappelmann-Fenzl M., Leal-Egaña A.:
3D hydrogel-based microcapsules as an in vitro model to study tumorigenicity, cell migration and drug resistance.
In: Acta Biomaterialia (2022)
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2022.02.010
Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf SA., Besch R., French LE., Matthies AO., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma
In: International Journal of Molecular Sciences 23 (2022), Art.Nr.: 849
ISSN: 1422-0067
DOI: 10.3390/ijms23020849
Linck-Paulus L., Kappelmann-Fenzl M., Meister G., Boßerhoff AK.:
An AGO2 variant affects the function of miRNAs and influences the viability of melanoma cells
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2022
Peschl V., Seitz T., Sommer J., Thasler W., Boßerhoff AK., Hellerbrand C.:
Bone morphogenetic protein 13 in hepatic stellate cells and hepatic fibrosis
In: Journal of Cellular Biochemistry (2022)
ISSN: 0730-2312
DOI: 10.1002/jcb.30248
Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models
In: Advanced Functional Materials Volume 32 (2022)
ISSN: 1616-301X
DOI: 10.1002/adfm.202107993
Schott M., Kappelmann-Fenz M., Fischer S., Fernandez-Barrena MG., Pineda-Lucena A., Ávila MA., Kuphal S., Boßerhoff AK.:
Impact of CYLD on chromatin structure and histone methylation in malignant melanoma
In: International Journal of Molecular Medicine 49 (2022), Art.Nr.: 66
ISSN: 1107-3756
DOI: 10.3892/ijmm.2022.5122
Weisenstein C., Richter M., Wigger AK., Boßerhoff AK., Haring Bolivar P.:
Substrate-integrated microfluidics for sensitive biosensing with complementary THz metamaterials in water
In: Applied Physics Letters 120 (2022)
ISSN: 0003-6951
DOI: 10.1063/5.0076379
Zimmermann T., Pommer M., Kluge V., Chiheb C., Mühlich S., Boßerhoff AK.:
Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
In: Cells 11 (2022), Art.Nr.: 1489
ISSN: 2073-4409
DOI: 10.3390/cells11091489

2021

Arndt S., Fadil F., Dettmer K., Unger P., Boskovic M., Samol C., Boßerhoff AK., Zimmermann JL., Gruber M., Gronwald W., Karrer S.:
Cold atmospheric plasma changes the amino acid composition of solutions and influences the anti‐tumor effect on melanoma cells
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 7886
ISSN: 1422-0067
DOI: 10.3390/ijms22157886
Arndt S., Fadil F., Dettmer K., Unger P., Boskovic M., Samol C., Boßerhoff AK., Zimmermann JL., Gruber M., Gronwald W., Karrer S.:
Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells
In: International Journal of Molecular Sciences 22 (2021)
ISSN: 1422-0067
DOI: 10.3390/ijms22157886
Arndt S., Unger P., Boßerhoff AK., Berneburg M., Karrer S.:
The anti-fibrotic effect of cold atmospheric plasma on localized scleroderma in vitro and in vivo
In: Biomedicines 9 (2021), Art.Nr.: 1545
ISSN: 2227-9059
DOI: 10.3390/biomedicines9111545
Arndt S., Unger P., Schneider C., Boßerhoff AK., Karrer S.:
Cold atmospheric plasma (CAP) for the selective control of tumor cells
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2021
Boßerhoff AK., Kappelmann-Fenzl M.:
Next Generation Sequencing (NGS): What Can Be Sequenced?
In: Kappelmann-Fenzl, Melanie (Hrsg.): Next Generation Sequencing and Data Analysis, Cham, Schweiz: Springer, 2021, S. 1-15 (Learning Materials in Bioscience)
ISBN: 978-3-030-62489-7
DOI: 10.1007/978-3-030-62490-3
Böhme-Schäfer I., Schoenherr R., Eberle J., Boßerhoff AK.:
Membrane Transporters and Channels in Melanoma
In: Reviews of Physiology Biochemistry and Pharmacology 181 (2021), S. 269-374
ISSN: 0303-4240
DOI: 10.1007/112_2020_17
Fritz V., Malek L., Gaza A., Wormser L., Appel M., Kremer A., Thasler WE., Siebler J., Neurath M., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Combined de‐repression of chemoresistance associated mitogen‐activated protein kinase 14 and activating transcription factor 2 by loss of microrna‐622 in hepatocellular carcinoma
In: Cancers 13 (2021), S. 1-14
ISSN: 2072-6694
DOI: 10.3390/cancers13051183
Fuentes Chandia MA., Vierling A., Kappelmann-Fenzl M., Monavari M., Letort G., Höne L., Parma B., Khan Antara S., Ertekin Ö., Palmisano R., Dong M., Böpple K., Boccaccini AR., Ceppi P., Boßerhoff AK., Leal-Egaña A.:
3D Spheroids Versus 3D Tumor-Like Microcapsules: Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells
In: Advanced Biology 5 (2021), S. e2000349
ISSN: 2701-0198
DOI: 10.1002/adbi.202000349
Fuentes-Chandía M., Vierling A., Kappelmann-Fenzl M., Monavari M., Letort G., Höne L., Parma B., Antara SK., Ertekin Ö., Palmisano R., Dong M., Böpple K., Boccaccini AR., Ceppi P., Boßerhoff AK., Leal-Egaña A.:
3D Spheroids Versus 3D Tumor-Like Microcapsules: Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells
In: Advanced Biology (2021)
ISSN: 2701-0198
DOI: 10.1002/adbi.202000349
Gaza A., Fritz V., Malek L., Wormser L., Treiber N., Danner J., Kremer AE., Thasler WE., Siebler J., Meister G., Neurath MF., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11
In: Neoplasia 23 (2021), S. 502-514
ISSN: 1522-8002
DOI: 10.1016/j.neo.2021.04.001
Haller L., Reichelt J., Boßerhoff AK., Kuphal S.:
The Role of NRN1 in the Development and Progression of malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Heppt M., Wessely A., Hornig E., Kammerbauer C., Graf S., Besch R., French LE., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK., Berking C.:
Brn3a expression is epigenetically controlled by HDAC2 in melanocytes and melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2021
Herr F., Schmidt S., Böhme I., Boßerhoff AK.:
Analysis of Glucose Concentration in Melanoma cells under physiological and nutrient-deficient Conditions
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Kappelmann-Fenzl M., Schmidt S., Fischer S., Schmid R., Lämmerhirt L., Fischer L., Schrüfer S., Thievessen I., Schubert DW., Matthies AO., Detsch R., Boccaccini AR., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
Molecular changes induced in melanoma by cell culturing in 3D alginate hydrogels
In: Cancers 13 (2021), Art.Nr.: 4111
ISSN: 2072-6694
DOI: 10.3390/cancers13164111
Kappelmann-Fenzl M., Schmidt S., Fischer S., Schmid R., Lämmerhirt L., Fischer L., Schrüfer S., Thievessen I., Schubert DW., Matthies AO., Detsch R., Boccaccini AR., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
Molecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels.
In: Cancers 13 (2021)
ISSN: 2072-6694
DOI: 10.3390/cancers13164111
Kappelmann-Fenzl M., Schmidt S., Fischer S., Schmid R., Lämmerhirt L., Fischer L., Schrüfer S., Thievessen I., Schubert DW., Matthies AO., Detsch R., Boccaccini AR., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
Molecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels
In: Cancers (2021), S. 72-72
ISSN: 2072-6694
DOI: 10.3390/cancers13164111
Kupke LS., Arndt S., Lenzer S., Metz S., Unger P., Zimmermann JL., Boßerhoff AK., Gruber M., Karrer S.:
Cold atmospheric plasma promotes the immunoreactivity of granulocytes in vitro
In: Biomolecules 11 (2021), Art.Nr.: 902
ISSN: 2218-273X
DOI: 10.3390/biom11060902
Kyjacova L., Saup R., Rothley M., Schmaus A., Wagner T., Boßerhoff AK., Garvalov BK., Thiele W., Sleeman JP.:
Quantitative detection of disseminated melanoma cells by trp-1 transcript analysis reveals stochastic distribution of pulmonary metastases
In: Journal of Clinical Medicine 10 (2021), Art.Nr.: 5459
ISSN: 2077-0383
DOI: 10.3390/jcm10225459
Linck-Paulus L., Lämmerhirt L., Voeller D., Meyer K., Engelmann JC., Spang R., Eichner N., Meister G., Kuphal S., Boßerhoff AK.:
Learning from Embryogenesis-A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development
In: Journal of Clinical Medicine 10 (2021)
ISSN: 2077-0383
DOI: 10.3390/jcm10112259
Pommer M., Kuphal S., Boßerhoff AK.:
Amphiregulin Regulates Melanocytic Senescence
In: Cells 10 (2021)
ISSN: 2073-4409
DOI: 10.3390/cells10020326
Rachinger N., Boßerhoff AK., Kuphal S.:
Sox21-transcriptional Regulation in malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Rachinger N., Fischer S., Böhme I., Linck-Paulus L., Kuphal S., Kappelmann-Fenzl M., Boßerhoff AK.:
Loss of gene information: Discrepancies between rna sequencing, cdna microarray, and qrt-pcr
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 9349
ISSN: 1422-0067
DOI: 10.3390/ijms22179349
Sasahira T., Kurihara-Shimomura M., Shimomura H., Boßerhoff AK., Kirita T.:
Identification of oral squamous cell carcinoma markers MUC2 and SPRR1B downstream of TANGO
In: Journal of Cancer Research and Clinical Oncology (2021)
ISSN: 0171-5216
DOI: 10.1007/s00432-021-03568-9
Schmid R., Schmidt S., Detsch R., Horder H., Blunk T., Schrüfer S., Schubert DW., Fischer L., Thievessen I., Heltmann-Meyer S., Steiner D., Schneidereit D., Friedrich O., Grüneboom A., Amouei H., Wajant H., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models
In: Advanced Functional Materials (2021)
ISSN: 1616-301X
DOI: 10.1002/adfm.202107993
URL: https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202107993
Seitz T., Hackl C., Freese K., Dietrich P., Mahli A., Thasler RM., Thasler WE., Lang SA., Boßerhoff AK., Hellerbrand C.:
Xanthohumol, a prenylated chalcone derived from hops, inhibits growth and metastasis of melanoma cells
In: Cancers 13 (2021), S. 1-12
ISSN: 2072-6694
DOI: 10.3390/cancers13030511
Stabler S., Rottensteiner-Brandl U., Boßerhoff AK.:
The Role of the Transcription Factor AP2e in the Development of malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2021
Weisenstein C., Wigger AK., Richter M., Sczech R., Boßerhoff AK., Bolivar PH.:
THz Detection of Biomolecules in Aqueous Environments-Status and Perspectives for Analysis Under Physiological Conditions and Clinical use
In: Journal of Infrared, Millimeter, and Terahertz Waves (2021)
ISSN: 1866-6892
DOI: 10.1007/s10762-021-00792-9
Zimmermann T., Gebhardt L., Kreiß L., Schneider C., Arndt S., Karrer S., Friedrich O., Fischer MJM., Boßerhoff AK.:
Acidified nitrite contributes to the antitumor effect of cold atmospheric plasma on melanoma cells
In: International Journal of Molecular Sciences 22 (2021), Art.Nr.: 3757
ISSN: 1422-0067
DOI: 10.3390/ijms22073757

2020

Arnold J., Engelmann JC., Schneider N., Boßerhoff AK., Kuphal S.:
miR-488-5p and its role in melanoma
In: Experimental and Molecular Pathology 112 (2020), Art.Nr.: 104348
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2019.104348
Dietrich P., Wormser L., Fritz V., Seitz T., de Maria M., Schambony A., Kremer A., Günther C., Itzel T., Thasler WE., Teufel A., Trebicka J., Hartmann A., Neurath M., von Hörsten S., Boßerhoff AK., Hellerbrand C.:
Molecular cross-talk between Y5-receptor and neuropeptide Y drives liver cancer
In: Journal of Clinical Investigation 130 (2020), S. 2509-2526
ISSN: 0021-9738
DOI: 10.1172/JCI131919
Koch A., Ebert EV., Seitz T., Dietrich P., Berneburg M., Boßerhoff AK., Hellerbrand C.:
Characterization of glycolysis-related gene expression in malignant melanoma
In: Pathology Research and Practice 216 (2020), Art.Nr.: 152752
ISSN: 0344-0338
DOI: 10.1016/j.prp.2019.152752
Kurihara–Shimomura M., Sasahira T., Shimomura H., Boßerhoff AK., Kirita T.:
Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma
In: International Journal of Oncology 56 (2020), S. 1093-1100
ISSN: 1019-6439
DOI: 10.3892/ijo.2020.4996
Liebig J., Kuphal S., Boßerhoff AK.:
Hurdling senescence: hur breaks braf-induced senescence in melanocytes and supports melanoma growth
In: Cancers 12 (2020), Art.Nr.: 1299
ISSN: 2072-6694
DOI: 10.3390/cancers12051299
Linck-Paulus L., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Dissimilar Appearances Are Deceptive-Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9010114
Penas C., Apraiz A., Muñoa I., Arroyo-Berdugo Y., Rasero J., Ezkurra PA., Velasco V., Subiran N., Boßerhoff AK., Alonso S., Asumendi A., Boyano MD.:
RKIP regulates differentiation-related features in melanocytic cells
In: Cancers 12 (2020), S. 1-22
ISSN: 2072-6694
DOI: 10.3390/cancers12061451
Petzer V., Tymoszuk P., Asshoff M., Carvalho J., Papworth J., Deantonio C., Bayliss L., Wake MS., Seifert M., Brigo N., Valente de Souza L., Hilbe R., Grubwieser P., Demetz E., Dichtl S., Volani C., Berger S., Böhm F., Hoffmann A., Pfeifhofer-Obermair C., von Raffay L., Sopper S., Arndt S., Boßerhoff AK., Kautz L., Perrier P., Nairz M., Wolf D., Weiss G., Germaschewski V., Theurl I.:
A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease
In: Blood 136 (2020), S. 1080-1090
ISSN: 0006-4971
DOI: 10.1182/blood.2019004653
Schmid R., Schmidt S., Hazur J., Detsch R., Maurer E., Boccaccini AR., Hauptstein J., Teßmar J., Blunk T., Schrüfer S., Schubert DW., Horch RE., Boßerhoff AK., Arkudas A., Kengelbach-Weigand A.:
Comparison of hydrogels for the development of well-defined 3d cancer models of breast cancer and melanoma
In: Cancers 12 (2020), S. 1-21
ISSN: 2072-6694
DOI: 10.3390/cancers12082320
Schmidt S., Schmid R., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
3D Bioprinting of Melanoma Cells with commercially available Bio Inks
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2020
Seitz T., Freese K., Dietrich P., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma
In: Scientific Reports 10 (2020), Art.Nr.: 4546
ISSN: 2045-2322
DOI: 10.1038/s41598-020-61510-4
Sommer J., Dorn C., Gaebele E., Bataille F., Freese K., Seitz T., Thasler WE., Buettner R., Weiskirchen R., Boßerhoff AK., Hellerbrand C.:
Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9010248
Weisenstein C., Schaar D., Wigger AK., Schäfer-Eberwein H., Boßerhoff AK., Bolívar PH.:
Ultrasensitive THz biosensor for PCR-free cDNA detection based on frequency selective surfaces
In: Biomedical Optics Express 11 (2020), S. 448-460
ISSN: 2156-7085
DOI: 10.1364/BOE.380818
Zimmermann T., Schneider C., Gebhardt L., Arndt S., Karrer S., Zimmermann JL., Fischer MJM., Boßerhoff AK.:
The molecular Effects of cold atmospheric Plasma on malignant Melanoma
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, HOBOKEN: 2020

2019

Arndt S., Karrer S., Hellerbrand C., Boßerhoff AK.:
Bone Morphogenetic Protein-6 Inhibits Fibrogenesis in Scleroderma Offering Treatment Options for Fibrotic Skin Disease
In: Journal of Investigative Dermatology (2019)
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.02.020
Arnold J., Engelmann JC., Schneider N., Boßerhoff AK., Kuphal S.:
miR-488-5p and its role in melanoma
In: Experimental and Molecular Pathology 112 (2019)
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2019.104348
Braun C., Schneider N., Pei D., Boßerhoff AK., Kuphal S.:
Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma
In: American Journal of Translational Research 11 (2019), S. 4425-+
ISSN: 1943-8141
Böhme I., Boßerhoff AK.:
Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells
In: Pigment Cell & Melanoma Research 33 (2019), S. 41-51
ISSN: 1755-1471
DOI: 10.1111/pcmr.12811
Datz E., Zeman F., Koller M., Szeimies RM., Berneburg M., Landthaler M., Boßerhoff AK., Karrer S.:
Phototherapy-induced elevation of serum level of melanoma inhibitory activity
In: Photodermatology Photoimmunology & Photomedicine 35 (2019), S. 255-260
ISSN: 0905-4383
DOI: 10.1111/phpp.12461
Dietrich P., Gaza A., Wormser L., Fritz V., Hellerbrand C., Boßerhoff AK.:
Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma
In: Neoplasia 21 (2019), S. 257-268
ISSN: 1522-8002
DOI: 10.1016/j.neo.2018.11.011
Dietrich P., Hellerbrand C., Boßerhoff AK.:
The delta subunit of rod-specific photoreceptor cgmp phosphodiesterase (Pde6d) contributes to hepatocellular carcinoma progression
In: Cancers 11 (2019), Art.Nr.: 398
ISSN: 2072-6694
DOI: 10.3390/cancers11030398
Feuerer L., Lamm S., Henz I., Kappelmann-Fenzl M., Haferkamp S., Meierjohann S., Hellerbrand C., Kuphal S., Boßerhoff AK.:
Role of melanoma inhibitory activity in melanocyte senescence
In: Pigment Cell & Melanoma Research (2019)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12801
Freese K., Dietrich P., Boßerhoff AK., Hellerbrand C.:
Variation of different histone deacetylases and the functional effects of HDAC inhibitors in hepatocellular carcinoma
International Liver Congress (Vienna, 10. April 2019 - 14. April 2019)
In: JOURNAL OF HEPATOLOGY, AMSTERDAM: 2019
Freese K., Seitz T., Dietrich P., Lee SM., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Histone deacetylase expressions in hepatocellular carcinoma and functional effects of histone deacetylase inhibitors on liver cancer cells in vitro
In: Cancers 11 (2019), Art.Nr.: 1587
ISSN: 2072-6694
DOI: 10.3390/cancers11101587
Graf SA., Heppt MV., Wessely A., Krebs S., Kammerbauer C., Hornig E., Strieder A., Blum H., Boßerhoff AK., Berking C.:
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion
In: Pigment Cell & Melanoma Research 32 (2019), S. 424-434
ISSN: 1755-1471
DOI: 10.1111/pcmr.12760
Kappelmann-Fenzl M., Gebhard C., Matthies AO., Kuphal S., Rehli M., Boßerhoff AK.:
C-Jun drives melanoma progression in PTEN wild type melanoma cells
In: Cell Death & Disease 10 (2019), Art.Nr.: 584
ISSN: 2041-4889
DOI: 10.1038/s41419-019-1821-9
Kappelmann-Fenzl M., Kuphal S., Krupar R., Schadendorf D., Umansky V., Vardimon L., Hellerbrand C., Boßerhoff AK.:
Complex formation with monomeric α-tubulin and importin 13 fosters c-jun protein stability and is required for c-jun’s nuclear translocation and activity
In: Cancers 11 (2019), Art.Nr.: 1806
ISSN: 2072-6694
DOI: 10.3390/cancers11111806
Linck-Paulus L., Voeller D., Meister G., Boßerhoff AK.:
Post-transcriptional regulation of Argonaute2 in malignant melanoma
In: EXPERIMENTAL DERMATOLOGY, HOBOKEN: 2019
Mahli A., Seitz T., Beckroege T., Freese K., Thasler WE., Benkert M., Dietrich P., Weiskirchen R., Boßerhoff AK., Hellerbrand C.:
Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro
In: Cells 8 (2019)
ISSN: 2073-4409
DOI: 10.3390/cells8050457
Schmidt S., Schmid R., Arkudas A., Kengelbach-Weigand A., Boßerhoff AK.:
Tumor Cells Develop Defined Cellular Phenotypes After 3D-Bioprinting in Different Bioinks
In: Cells 8 (2019)
ISSN: 2073-4409
DOI: 10.3390/cells8101295
Schneider C., Gebhardt L., Arndt S., Karrer S., Zimmermann JL., Fischer M., Boßerhoff AK.:
Acidification is an essential process of cold atmospheric plasma and promotes the anti-cancer effect on malignant melanoma cells
In: Cancers 11 (2019), Art.Nr.: 671
ISSN: 2072-6694
DOI: 10.3390/cancers11050671
Stieglitz D., Lamm S., Braig S., Feuerer L., Kuphal S., Dietrich P., Arndt S., Echtenacher B., Hellerbrand C., Karrer S., Boßerhoff AK.:
BMP6-induced modulation of the tumor micro-milieu
In: Oncogene 38 (2019), S. 609-621
ISSN: 0950-9232
DOI: 10.1038/s41388-018-0475-x
Weisenstein C., Schmeck M., Schaar D., Wigger AK., Boßerhoff AK., Bolivar PH.:
Quantification of dsDNA functionalization efficiency in THz biosensors
44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019 (Paris, 1. September 2019 - 6. September 2019)
In: International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019
DOI: 10.1109/IRMMW-THz.2019.8873759
de Jel MM., Schott M., Lamm S., Neuhuber W., Kuphal S., Boßerhoff AK.:
Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model
In: Oncogenesis 8 (2019), Art.Nr.: 56
ISSN: 2157-9024
DOI: 10.1038/s41389-019-0169-4

2018

Böhme I., Boßerhoff AK.:
Extracellular Acidosis leads to the Development of a senescent-like Phenotype and molecular Reprogramming of human Melanoma Cells
Dietrich P., Freese K., Mahli A., Thasler WE., Hellerbrand C., Boßerhoff AK.:
Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option
In: Oncotarget 9 (2018), S. 3605-3618
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23188
Dietrich P., Kuphal S., Spruss T., Hellerbrand C., Boßerhoff AK.:
MicroRNA-622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma
In: Pigment Cell & Melanoma Research (2018)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12698
Kirchberger MC., Schilling B., Haferkamp S., Boßerhoff AK., Schuler G., Heinzerling L.:
Can checkpoint inhibitor therapy improve response to chemotherapy?
In: Journal of Cancer Research and Clinical Oncology 144 (2018), S. 183-185
ISSN: 0171-5216
DOI: 10.1007/s00432-017-2546-8
Kunz M., Loeffler-Wirth H., Dannemann M., Willscher E., Doose G., Kelso J., Kottek T., Nickel B., Hopp L., Landsberg J., Hoffmann S., Tueting T., Zigrino P., Mauch C., Utikal J., Ziemer M., Schulze HJ., Holzel M., Roesch A., Kneitz S., Meierjohann S., Boßerhoff AK., Binder H., Schartl M.:
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas
In: Oncogene 37 (2018), S. 6136-6151
ISSN: 0950-9232
DOI: 10.1038/s41388-018-0385-y
Larribere L., Kuphal S., Sachpekidis C., Hueser L., Boßerhoff AK., Utikal J.:
Targeted Therapy-Resistant Melanoma Cells Acquire Transcriptomic Similarities with Human Melanoblasts
In: Cancers 10 (2018)
ISSN: 2072-6694
DOI: 10.3390/cancers10110451
Liebig J., Boßerhoff AK.:
Importance of the RNA Binding Protein Hu-antigen R in malignant Melanoma
Linck L., Boßerhoff AK.:
SiRNA-Knockdown einer neuen Argonaute2 Spleißvariante verringert die tumorigenen Eigenschaften von Melanomzellen.
28. Deutscher Hautkrebskongress (, 13. September 2018 - 15. September 2018)
In: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2018
Linck L., Liebig J., Voeller D., Eichner N., Lehmann G., Meister G., Boßerhoff AK.:
MicroRNA-sequencing data analyzing melanoma development and progression
In: Experimental and Molecular Pathology 105 (2018), S. 371-379
ISSN: 0014-4800
DOI: 10.1016/j.yexmp.2018.11.001
Mahli A., Koch A., Fresse K., Schiergens T., Thasler WE., Schoenberger C., Bergheim I., Boßerhoff AK., Hellerbrand C.:
Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis
In: Laboratory Investigation 98 (2018), S. 1614-1626
ISSN: 0023-6837
DOI: 10.1038/s41374-018-0112-x
Rottensteiner-Brandl U., Detsch R., Sarker B., Lingens L., Köhn K., Kneser U., Boßerhoff AK., Horch RE., Boccaccini AR., Arkudas A.:
Encapsulation of Rat Bone Marrow Derived Mesenchymal Stem Cells in Alginate Dialdehyde/Gelatin Microbeads with and without Nanoscaled Bioactive Glass for In Vivo Bone Tissue Engineering.
In: Materials 11 (2018)
ISSN: 1996-1944
DOI: 10.3390/ma11101880
Sasahira T., Boßerhoff AK., Kirita T.:
The importance of melanoma inhibitory activity gene family in the tumor progression of oral cancer
In: Pathology International 68 (2018), S. 278-286
ISSN: 1320-5463
DOI: 10.1111/pin.12672
Schneider C., Arndt S., Zimmermann JL., Li Y., Karrer S., Boßerhoff AK.:
Cold atmospheric plasma treatment inhibits growth in colorectal cancer cells
In: Biological Chemistry 400 (2018), S. 111-122
ISSN: 1431-6730
DOI: 10.1515/hsz-2018-0193
Schneider C., Gebhardt L., Arndt S., Karrer S., Zimmermann JL., Fischer M., Boßerhoff AK.:
Cold atmospheric plasma causes a calcium influx in melanoma cells triggering CAP-induced senescence
In: Scientific Reports 8 (2018)
ISSN: 2045-2322
DOI: 10.1038/s41598-018-28443-5
Schott M., de Jel MM., Boßerhoff AK., Kuphal S.:
CYLD - A potential Mediator of tissue-specific Melanoma Metastasis
Schott M., de Jel MM., Engelmann JC., Renner P., Geissler EK., Boßerhoff AK., Kuphal S.:
Selenium-binding protein 1 is down-regulated in malignant melanoma
In: Oncotarget 9 (2018), S. 10445-10456
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23853

2017

Arndt S., Unger P., Berneburg M., Boßerhoff AK., Karrer S.:
Cold atmospheric plasma (CAP) activates angiogenesis-related molecules in skin keratinocytes, fibroblasts and endothelial cells and improves wound angiogenesis in an autocrine and paracrine mode
In: Journal of Dermatological Science (2017)
ISSN: 0923-1811
DOI: 10.1016/j.jdermsci.2017.11.008
Boßerhoff AK., Schneider N., Ellmann L., Heinzerling L., Kuphal S.:
The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry
In: Oncotarget 8 (2017), S. 1117-1131
ISSN: 1949-2553
DOI: 10.18632/oncotarget.13585
Boßerhoff AK., Schuler G., Heinzerling L., Schilling B., Haferrkamp S., Kirchberger M.:
Can checkpoint inhibitor therapy improve response to chemotherapy?
Christoph J., Knell C., Boßerhoff AK., Naschberger E., Stürzl M., Rübner M., Seuß H., Ruh M., Prokosch HU., Sedlmayr B.:
Usability and Suitability of the Omics-Integrating Analysis Platform tranSMART for Translational Research and Education
In: Applied Clinical Informatics 8 (2017), S. 1173-1183
ISSN: 1869-0327
DOI: 10.4338/ACI-2017-05-RA-0085
Dietrich P., Boßerhoff AK.:
Melanoma sponge on pigmentation gene to reduce tumour-suppressive microRNAs
In: Pigment Cell & Melanoma Research (2017)
ISSN: 1755-1471
DOI: 10.1111/pcmr.12660
Dietrich P., Koch A., Fritz V., Hartmann A., Boßerhoff AK., Hellerbrand C.:
Wild type Kirsten rat sarcoma is a novel microRNA-622-regulated therapeutic target for hepatocellular carcinoma and contributes to sorafenib resistance
In: Gut (2017)
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2017-315402
Dietrich P., Kuphal S., Spruss T., Hellerbrand C., Boßerhoff AK.:
Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition
In: Oncogene (2017)
ISSN: 0950-9232
DOI: 10.1038/onc.2017.391
Krupar R., Hautmann MG., Pathak RR., Varier I., Mclaren C., Gaag D., Hellerbrand C., Evert M., Laban S., Idel C., Sandulache V., Perner S., Boßerhoff AK., Sikora AG.:
Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma
In: American Journal of Pathology (2017)
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2017.09.013
Kuphal S., Schneider N., Massoumi R., Hellerbrand C., Boßerhoff AK.:
UVB radiation represses CYLD expression in melanocytes
In: Oncology Letters 14 (2017), S. 7262-7268
ISSN: 1792-1074
DOI: 10.3892/ol.2017.7120
Mahli A., Saugspier M., Koch A., Sommer J., Dietrich P., Lee S., Thasler R., Schulze-Luehrmann J., Lührmann A., Thasler WE., Müller M., Boßerhoff AK., Hellerbrand C.:
ERK activation and autophagy impairment are central mediators of irinotecan-induced steatohepatitis
In: Gut (2017)
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2016-312485
Maisch T., Boßerhoff AK., Unger P., Heider J., Shimizu T., Zimmermann JL., Morfill GE., Landthaler M., Karrer S.:
Investigation of toxicity and mutagenicity of cold atmospheric argon plasma
In: ENVIRON MOL MUTAGEN 58 (2017), S. 172-177
ISSN: 0893-6692
DOI: 10.1002/em.22086
Maurus K., Hufnagel A., Geiger F., Graf S., Berking C., Heinemann A., Paschen A., Kneitz S., Stigloher C., Geissinger E., Otto C., Boßerhoff AK., Schartl M., Meierjohann S.:
The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformation
In: Oncogene 36 (2017), S. 5110-5121
ISSN: 0950-9232
DOI: 10.1038/onc.2017.135
Meyer T., Koch A., Ebert EV., Czech B., Mueller M., Boßerhoff AK., Lang SA., Hellerbrand C.:
Effect of melanoma cells on proliferation and migration of activated hepatic stellate cells in vitro
In: Pathology Research and Practice 213 (2017), S. 400-404
ISSN: 0344-0338
DOI: 10.1016/j.prp.2016.12.014
Sommer J., Mahli A., Freese K., Schiergens TS., Kuecuekoktay FS., Teufel A., Thasler WE., Mueller M., Boßerhoff AK., Hellerbrand C.:
Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice
In: Oncotarget 8 (2017), S. 13059-13072
ISSN: 1949-2553
DOI: 10.18632/oncotarget.14371
Uslu U., Schliep S., Schliep K., Erdmann M., Koch HU., Parsch H., Rosenheinrich S., Anzengruber D., Boßerhoff AK., Schuler G., Schuler-Thurner B.:
Comparison of the Serum Tumor Markers S100 and Melanoma-inhibitory Activity (MIA) in the Monitoring of Patients with Metastatic Melanoma Receiving Vaccination Immunotherapy with Dendritic Cells
In: Anticancer Research 37 (2017), S. 5033-5037
ISSN: 0250-7005
DOI: 10.21873/anticanres.11918

2016

Böhme I., Boßerhoff AK.:
Acidic tumor microenvironment in human melanoma
In: Pigment Cell & Melanoma Research 29 (2016), S. 508-23
ISSN: 1755-1471
DOI: 10.1111/pcmr.12495
Dietrich P., Boßerhoff AK.:
DNMT targets MiRacle torching TORCh
In: Pigment Cell & Melanoma Research 29 (2016), S. 399-401
ISSN: 1755-1471
DOI: 10.1111/pcmr.12484
Henrich F., Singer K., Poller K., Bernhardt L., Strobl C., Limm K., Ritter AP., Gottfried E., Voelkl S., Jacobs B., Peter K., Mougiakakos D., Dettmer K., Oefner PJ., Boßerhoff AK., Kreutz MP., Aigner M., Mackensen A.:
Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cells
In: OncoImmunology 5 (2016), S. e1184802
ISSN: 2162-4011
DOI: 10.1080/2162402X.2016.1184802
Limm K., Dettmer K., Reinders J., Oefner PJ., Boßerhoff AK.:
Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma
In: PLoS ONE 11 (2016), S. e0160348
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0160348
Moeckel S., Vollmann-Zwerenz A., Proescholdt M., Brawanski A., Riemenschneider MJ., Bogdahn U., Boßerhoff AK., Spang R., Hau P.:
Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro
In: PLoS ONE 11 (2016), S. e0151312
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0151312
Ott C., Linck L., Kremmer E., Meister G., Boßerhoff AK.:
Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells
In: Oncotarget (2016)
ISSN: 1949-2553
DOI: 10.18632/oncotarget.11410
Reinders Y., Voeller D., Boßerhoff AK., Oefner PJ., Reinders J.:
Testing Suitability of Cell Cultures for SILAC-Experiments Using SWATH-Mass Spectrometry
In: Methods in Molecular Biology 1394 (2016), S. 101-8
ISSN: 1064-3745
DOI: 10.1007/978-1-4939-3341-9_8
Sasahira T., Kirita T., Nishiguchi Y., Kurihara M., Nakashima C., Boßerhoff AK., Kuniyasu H.:
A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma
In: Oncotarget 7 (2016), S. 31137-52
ISSN: 1949-2553
DOI: 10.18632/oncotarget.9082
Sasahira T., Nishiguchi Y., Fujiwara R., Kurihara M., Kirita T., Boßerhoff AK., Kuniyasu H.:
Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression
In: Oncotarget 7 (2016), S. 26751-64
ISSN: 1949-2553
DOI: 10.18632/oncotarget.8495
Schummer P., Kuphal S., Vardimon L., Boßerhoff AK., Kappelmann M.:
Specific c-Jun target genes in malignant melanoma
In: Cancer Biology & Therapy 17 (2016), S. 486-97
ISSN: 1538-4047
DOI: 10.1080/15384047.2016.1156264
Sommer J., Mahli A., Freese K., Thasler W., Kuecuekoktay F., Boßerhoff AK., Mueller M., Hellerbrand C.:
ANALYSIS OF MOLECULAR MECHANISMS OF 5-FLUOROURACIL INDUCED STEATOSIS AND INFLAMMATION IN VITRO AND IN MICE
Voeller D., Linck L., Bruckmann A., Hauptmann J., Deutzmann R., Meister G., Boßerhoff AK.:
Argonaute Family Protein Expression in Normal Tissue and Cancer Entities
In: PLoS ONE 11 (2016), S. e0161165
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0161165
de Jel MM., Schiffner S., Kuphal S., Boßerhoff AK.:
Loss of CYLD promotes melanoma progression

2015

Arndt S., Landthaler M., Zimmermann JL., Unger P., Wacker E., Shimizu T., Li YF., Morfill GE., Boßerhoff AK., Karrer S.:
Effects of Cold Atmospheric Plasma (CAP) on ß-Defensins, Inflammatory Cytokines, and Apoptosis-Related Molecules in Keratinocytes In Vitro and In Vivo
In: PLoS ONE 10 (2015), S. e0120041
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0120041
Dietrich P., Boßerhoff AK.:
Modifying microRNAs--another piece of the melanoma puzzle
In: Pigment Cell & Melanoma Research 28 (2015), S. 488-9
ISSN: 1755-1471
DOI: 10.1111/pcmr.12389
Koch A., Lang SA., Wild PJ., Gantner S., Mahli A., Spanier G., Berneburg M., Mueller M., Boßerhoff AK., Hellerbrand C.:
Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells
In: Oncotarget 6 (2015), S. 32748-60
ISSN: 1949-2553
DOI: 10.18632/oncotarget.4977
Mione M., Boßerhoff AK.:
MicroRNAs in melanocyte and melanoma biology
In: Pigment Cell & Melanoma Research 28 (2015), S. 340-54
ISSN: 1755-1471
DOI: 10.1111/pcmr.12346
Niebler S., Angele P., Kujat R., Boßerhoff AK.:
Hypoxia-Inducible Factor 1 Is an Inductor of Transcription Factor Activating Protein 2 Epsilon Expression during Chondrogenic Differentiation
In: BioMed Research International 2015 (2015), S. 380590
ISSN: 2314-6133
DOI: 10.1155/2015/380590
Niebler S., Schubert T., Hunziker EB., Boßerhoff AK.:
Activating enhancer binding protein 2 epsilon (AP-2?)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development
In: Arthritis Research & Therapy 17 (2015), S. 119
ISSN: 1478-6362
DOI: 10.1186/s13075-015-0648-8
Ruedel A., Dietrich P., Schubert T., Hofmeister S., Hellerbrand C., Boßerhoff AK.:
Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts
In: International Journal of Clinical and Experimental Pathology 8 (2015), S. 4953-62
ISSN: 1936-2625

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