Publikationen
2020
Dietrich P. , Wormser L. , Fritz V. , Seitz T. , de Maria M. , Schambony A. , Kremer A. , Günther C. , Itzel T. , Thasler WE. , Teufel A. , Trebicka J. , Hartmann A. , Neurath M. , von Hörsten S. , Boßerhoff AK. , Hellerbrand C. :Molecular cross-talk between Y5-receptor and neuropeptide Y drives liver cancer In: Journal of Clinical Investigation (2020 )ISSN: 0021-9738 DOI: 10.1172/JCI131919
Jefremow A. , Wiesmüller M. , Rouse RA. , Dietrich P. , Kremer A. , Waldner M. , Neurath M. , Siebler J. :Efficiency and Toxicity of Lenvatinib in Advanced HCC in Later Treatment Lines In: ONCOLOGY RESEARCH AND TREATMENT , BASEL : 2020
Koch A. , Ebert EV. , Seitz T. , Dietrich P. , Berneburg M. , Boßerhoff AK. , Hellerbrand C. :Characterization of glycolysis-related gene expression in malignant melanoma In: Pathology Research and Practice 216 (2020 )ISSN: 0344-0338 DOI: 10.1016/j.prp.2019.152752
Linck-Paulus L. , Hellerbrand C. , Boßerhoff AK. , Dietrich P. :Dissimilar Appearances Are Deceptive-Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma In: Cells 9 (2020 )ISSN: 2073-4409 DOI: 10.3390/cells9010114
Schierwagen R. , Dietrich P. , Klein S. , Uschner FE. , Ortiz C. , Tyc O. , Torres S. , Hellerbrand C. , Sauerbruch T. , Trebicka J. :β-Arrestin2 is increased in liver fibrosis in humans and rodents In: Proceedings of the National Academy of Sciences of the United States of America 117 (2020 ), S. 27082-27084 ISSN: 0027-8424 DOI: 10.1073/pnas.2014337117
Seitz T. , Freese K. , Dietrich P. , Thasler WE. , Boßerhoff AK. , Hellerbrand C. :Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma In: Scientific Reports 10 (2020 ), Art.Nr.: 4546 ISSN: 2045-2322 DOI: 10.1038/s41598-020-61510-4
Simon D. , Tascilar K. , Krönke G. , Kleyer A. , Zaiss M. , Heppt F. , Meder C. , Atreya R. , Klenske E. , Dietrich P. , Abdullah A. , Kliem T. , Corte G. , Morf H. , Leppkes M. , Kremer A. , Ramming A. , Pachowsky M. , Schuch F. , Ronneberger M. , Kleinert S. , Maier C. , Hueber A. , Manger K. , Manger B. , Berking C. , Tenbusch M. , Überla K. , Sticherling M. , Neurath M. , Schett G. :Patients Receiving Cytokine Inhibitors Have Low Prevalence of SARS-CoV-2 Infection In: ARTHRITIS & RHEUMATOLOGY , HOBOKEN : 2020
Simon D. , Tascilar K. , Krönke G. , Kleyer A. , Zaiss M. , Heppt F. , Meder C. , Atreya R. , Klenske E. , Dietrich P. , Abdullah A. , Kliem T. , Corte G. , Morf H. , Leppkes M. , Kremer A. , Ramming A. , Pachowsky M. , Schuch F. , Ronneberger M. , Kleinert S. , Meier C. , Hueber A. , Manger K. , Manger B. , Berking C. , Tenbusch M. , Überla K. , Sticherling M. , Neurath M. , Schett G. :Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion In: Nature Communications 11 (2020 ), Art.Nr.: 3774 ISSN: 2041-1723 DOI: 10.1038/s41467-020-17703-6
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2019
Dietrich P. , Gaza A. , Wormser L. , Fritz V. , Hellerbrand C. , Boßerhoff AK. :Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma In: Neoplasia 21 (2019 ), S. 257-268 ISSN: 1522-8002 DOI: 10.1016/j.neo.2018.11.011
Dietrich P. , Hellerbrand C. , Boßerhoff AK. :The delta subunit of rod-specific photoreceptor cgmp phosphodiesterase (Pde6d) contributes to hepatocellular carcinoma progression In: Cancers 11 (2019 ), Art.Nr.: 398 ISSN: 2072-6694 DOI: 10.3390/cancers11030398
Freese K. , Dietrich P. , Boßerhoff AK. , Hellerbrand C. :Variation of different histone deacetylases and the functional effects of HDAC inhibitors in hepatocellular carcinoma International Liver Congress (Vienna , 10. April 2019 - 14. April 2019 )In: JOURNAL OF HEPATOLOGY , AMSTERDAM : 2019
Freese K. , Seitz T. , Dietrich P. , Lee SM. , Thasler WE. , Boßerhoff AK. , Hellerbrand C. :Histone deacetylase expressions in hepatocellular carcinoma and functional effects of histone deacetylase inhibitors on liver cancer cells in vitro In: Cancers 11 (2019 ), Art.Nr.: 1587 ISSN: 2072-6694 DOI: 10.3390/cancers11101587
Goeppert B. , Truckenmueller F. , Ori A. , Fritz V. , Albrecht T. , Fraas A. , Scherer D. , Silos RG. , Sticht C. , Gretz N. , Mehrabi A. , Bewerunge-Hudler M. , Pusch S. , Bermejo JL. , Dietrich P. , Schirmacher P. , Renner M. , Roessler S. :Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p In: Scientific Reports 9 (2019 )ISSN: 2045-2322 DOI: 10.1038/s41598-019-40857-3
Koch A. , Ebert EV. , Seitz T. , Dietrich P. , Berneburg M. , Boßerhoff AK. , Hellerbrand C. :Characterization of glycolysis-related gene expression in malignant melanoma In: Pathology Research and Practice (2019 ), Art.Nr.: 152752 ISSN: 0344-0338 DOI: 10.1016/j.prp.2019.152752
Mahli A. , Seitz T. , Beckroege T. , Freese K. , Thasler WE. , Benkert M. , Dietrich P. , Weiskirchen R. , Boßerhoff AK. , Hellerbrand C. :Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro In: Cells 8 (2019 )ISSN: 2073-4409 DOI: 10.3390/cells8050457
Stieglitz D. , Lamm S. , Braig S. , Feuerer L. , Kuphal S. , Dietrich P. , Arndt S. , Echtenacher B. , Hellerbrand C. , Karrer S. , Boßerhoff AK. :BMP6-induced modulation of the tumor micro-milieu In: Oncogene 38 (2019 ), S. 609-621 ISSN: 0950-9232 DOI: 10.1038/s41388-018-0475-x
2018
Dietrich P. , Freese K. , Mahli A. , Thasler WE. , Hellerbrand C. , Boßerhoff AK. :Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic "dual-hit" option In: Oncotarget 9 (2018 ), S. 3605-3618 ISSN: 1949-2553 DOI: 10.18632/oncotarget.23188
Dietrich P. , Kuphal S. , Spruss T. , Hellerbrand C. , Boßerhoff AK. :MicroRNA-622 is a novel mediator of tumorigenicity in melanoma by targeting Kirsten rat sarcoma In: Pigment Cell & Melanoma Research (2018 )ISSN: 1755-1471 DOI: 10.1111/pcmr.12698
Schmidt KM. , Dietrich P. , Hackl C. , Guenzle J. , Bronsert P. , Wagner C. , Fichtner-Feigl S. , Schlitt HJ. , Geissler EK. , Hellerbrand C. , Lang SA. :Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis In: Neoplasia 20 (2018 ), S. 1198-1208 ISSN: 1522-8002 DOI: 10.1016/j.neo.2018.10.001
2017
Dietrich P. , Boßerhoff AK. :Melanoma sponge on pigmentation gene to reduce tumour-suppressive microRNAs In: Pigment Cell & Melanoma Research (2017 )ISSN: 1755-1471 DOI: 10.1111/pcmr.12660
Dietrich P. , Koch A. , Fritz V. , Hartmann A. , Boßerhoff AK. , Hellerbrand C. :Wild type Kirsten rat sarcoma is a novel microRNA-622-regulated therapeutic target for hepatocellular carcinoma and contributes to sorafenib resistance In: Gut (2017 )ISSN: 0017-5749 DOI: 10.1136/gutjnl-2017-315402
Dietrich P. , Kuphal S. , Spruss T. , Hellerbrand C. , Boßerhoff AK. :Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition In: Oncogene (2017 )ISSN: 0950-9232 DOI: 10.1038/onc.2017.391
Mahli A. , Saugspier M. , Koch A. , Sommer J. , Dietrich P. , Lee S. , Thasler R. , Schulze-Luehrmann J. , Lührmann A. , Thasler WE. , Müller M. , Boßerhoff AK. , Hellerbrand C. :ERK activation and autophagy impairment are central mediators of irinotecan-induced steatohepatitis In: Gut (2017 )ISSN: 0017-5749 DOI: 10.1136/gutjnl-2016-312485
2015
Dietrich P. , Boßerhoff AK. :Modifying microRNAs--another piece of the melanoma puzzle In: Pigment Cell & Melanoma Research 28 (2015 ), S. 488-9 ISSN: 1755-1471 DOI: 10.1111/pcmr.12389
Hartl J. , Dietrich P. , Moleda L. , Mueller-Schilling M. , Wiest R. :Neuropeptide Y restores non-receptor-mediated vasoconstrictive action in superior mesenteric arteries in portal hypertension In: Liver International 35 (2015 ), S. 2556-63 ISSN: 1478-3223 DOI: 10.1111/liv.12874
Ruedel A. , Dietrich P. , Schubert T. , Hofmeister S. , Hellerbrand C. , Boßerhoff AK. :Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts In: International Journal of Clinical and Experimental Pathology 8 (2015 ), S. 4953-62 ISSN: 1936-2625