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  2. Medizinische Fakultät

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    • AG Bosserhoff (Lehrstuhl 1)
    • AG Wegner (Lehrstuhl 2)
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  3. AG Wegner (Lehrstuhl 2)
  4. Publikationen Lehrstuhl 2

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  • AG Bosserhoff (Lehrstuhl 1)
  • AG Wegner (Lehrstuhl 2)
    • Publikationen Lehrstuhl 2
  • AG Enz
  • AG Hellerbrand
  • AG Karow
  • AG Lie
  • AG Sticht
  • AG Dietrich
  • AG Falk
  • AG Beckervordersandforth
  • AG Hashemolhosseini
  • AG Kuphal
  • AG Küspert
  • AG Becker
  • AG Sagner
  • AG Hannappel
  • AG Sock

Publikationen Lehrstuhl 2

Publikationen LS2

Für weitere Publikationen besuchen Sie bitte Pubmed

  • Aberle T., Walter A., Piefke S., Hillgärtner S., Wüst H., Wegner M., Küspert M.:
    Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop
    In: International Journal of Molecular Sciences 25 (2024), Art.Nr.: 5234
    ISSN: 1422-0067
    DOI: 10.3390/ijms25105234
  • Jörg LM., Schlötzer-Schrehardt U., Lefebvre V., Sock E., Wegner M.:
    Transcription Factors Sox8 and Sox10 Contribute with Different Importance to the Maintenance of Mature Oligodendrocytes
    In: International Journal of Molecular Sciences 25 (2024), Art.Nr.: 8754
    ISSN: 1422-0067
    DOI: 10.3390/ijms25168754
  • Kremp M., Aberle T., Sock E., Bohl B., Hillgärtner S., Winkler J., Wegner M.:
    Transcription factor Olig2 is a major downstream effector of histone demethylase Phf8 during oligodendroglial development
    In: Glia 72 (2024), S. 1435-1450
    ISSN: 0894-1491
    DOI: 10.1002/glia.24538
  • Liu X., Xin DE., Zhong X., Zhao C., Li Z., Zhang L., Dourson AJ., Lee L., Mishra S., Bayat AE., Nicholson E., Seibel WL., Yan B., Mason J., Turner BJ., Gonsalvez DG., Ong W., Chew SY., Ghosh B., Yoon SO., Xin M., He Z., Tchieu J., Wegner M., Nave KA., Franklin RJ., Dutta R., Trapp BD., Hu M., Smith MA., Jankowski MP., Barton SK., He X., Lu QR.:
    Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
    In: Cell 187 (2024), S. 2465-2484.e22
    ISSN: 0092-8674
    DOI: 10.1016/j.cell.2024.04.005
  • Peters C., Aberle T., Sock E., Brunner J., Küspert M., Hillgärtner S., Wüst H., Wegner M.:
    Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development
    In: Cells 13 (2024), Art.Nr.: 1159
    ISSN: 2073-4409
    DOI: 10.3390/cells13131159
  • Rupprecht J., Reiprich S., Baroti T., Christoph C., Sock E., Fröb F., Wegner M.:
    Transcription Factors Sox2 and Sox3 Directly Regulate the Expression of Genes Involved in the Onset of Oligodendrocyte Differentiation
    In: Cells 13 (2024), Art.Nr.: 935
    ISSN: 2073-4409
    DOI: 10.3390/cells13110935
  • Schmidt AL., Kremp M., Aratake T., Cui S., Lin Y., Zhong X., Lu QR., Zhang C., Qiu M., Aberle T., Wegner M.:
    The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation
    In: Glia (2024)
    ISSN: 0894-1491
    DOI: 10.1002/glia.24530

  • Freudenstein D., Lippert M., Popp JS., Aprato J., Wegner M., Sock E., Haase S., Linker RA., González Alvarado MN.:
    Endogenous Sox8 is a critical factor for timely remyelination and oligodendroglial cell repletion in the cuprizone model
    In: Scientific Reports 13 (2023), Art.Nr.: 22272
    ISSN: 2045-2322
    DOI: 10.1038/s41598-023-49476-5
  • Gehlen-Breitbach S., Schmid T., Fröb F., Rodrian G., Weider M., Wegner M., Gölz L.:
    The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development
    In: International Journal of Oral Science 15 (2023), S. 16-
    ISSN: 1674-2818
    DOI: 10.1038/s41368-023-00222-7
  • Hassel L., Fröb F., Küspert M., Hillgärtner S., Arnold P., Huang W., Kirchhoff F., Wegner M.:
    Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells
    In: Glia (2023)
    ISSN: 0894-1491
    DOI: 10.1002/glia.24373
  • Kozlenkov A., Vadukapuram R., Zhou P., Fam P., Wegner M., Dracheva S.:
    Novel method of isolating nuclei of human oligodendrocyte precursor cells reveals substantial developmental changes in gene expression and H3K27ac histone modification
    In: Glia (2023)
    ISSN: 0894-1491
    DOI: 10.1002/glia.24462
  • Waldhauser V., Baroti T., Fröb F., Wegner M.:
    PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development
    In: Cells 12 (2023), Art.Nr.: 1556
    ISSN: 2073-4409
    DOI: 10.3390/cells12121556

  • Aberle T., Piefke S., Hillgärtner S., Tamm ER., Wegner M., Küspert M.:
    Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program
    In: Nucleic Acids Research 50 (2022), S. 1951-1968
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkac042
  • Bernhardt C., Sock E., Fröb F., Hillgärtner S., Nemer M., Wegner M.:
    KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
    In: Nucleic Acids Research (2022)
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkac953
  • Fröb F., Wegner M.:
    Coordination of Schwann cell myelination and node formation at the transcriptional level
    In: Neural Regeneration Research 17 (2022), S. 1269-1270
    ISSN: 1673-5374
    DOI: 10.4103/1673-5374.327343
  • Polanetzki V., Fröb F., Baroti T., Schimmel M., Tamm ER., Wegner M.:
    Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development
    In: Scientific Reports 12 (2022), S. 2651-
    ISSN: 2045-2322
    DOI: 10.1038/s41598-022-06588-8

  • Aberle T., Piefke S., Hillgärtner S., Schimmel M., Tamm ER., Wegner M., Küspert M.:
    Zinc-finger transcription factor Zfp276 acts as a novel regulator of oligodendroglial differentiation
    In: GLIA, HOBOKEN: 2021
  • Bernhardt C., Sock E., Wegner M.:
    Analysis of Kruppel like factors in oligodendroglial differentiation and myelin gene expression
    In: GLIA, HOBOKEN: 2021
  • Engler L., Wegner M.:
    Analysis of ectopic Sox9 expression in NG2 glia of the adult murine brain
    In: GLIA, HOBOKEN: 2021
  • Froeb-Thiele F., Tamm ER., Eichele G., Wegner M.:
    The Influence of the histone acetylase Tip60 on Schwann Cell Development in mice
    In: GLIA, HOBOKEN: 2021
  • Ittner E., Hartwig A., Elsesser O., Wüst H., Fröb F., Wedel M., Schimmel M., Tamm ER., Wegner M., Sock E.:
    SoxD transcription factor deficiency in Schwann cells delays myelination in the developing peripheral nervous system
    In: Scientific Reports 11 (2021), Art.Nr.: 14044
    ISSN: 2045-2322
    DOI: 10.1038/s41598-021-93437-9
  • Munguba H., Chattopadhyaya B., Nilsson S., Carrico JN., Memic F., Oberst P., Batista-Brito R., Munoz-Manchado AB., Wegner M., Fishell G., Di Cristo G., Hjerling-Leffler J.:
    Postnatal Sox6 Regulates Synaptic Function of Cortical Parvalbumin-Expressing Neurons
    In: Journal of Neuroscience 41 (2021), S. 8876-8886
    ISSN: 0270-6474
    DOI: 10.1523/JNEUROSCI.0021-21.2021
  • Saur AL., Fröb F., Weider M., Wegner M.:
    Formation of the node of Ranvier by Schwann cells is under control of transcription factor Sox10
    In: Glia (2021)
    ISSN: 0894-1491
    DOI: 10.1002/glia.23973
  • Sock E., Wegner M.:
    Using the lineage determinants Olig2 and Sox10 to explore transcriptional regulation of oligodendrocyte development
    In: Developmental Neurobiology (2021)
    ISSN: 1932-8451
    DOI: 10.1002/dneu.22849
  • Vogel J., Wegner M.:
    Sox9 in the developing central nervous system: A jack of all trades?
    In: Neural Regeneration Research 16 (2021), S. 676-677
    ISSN: 1673-5374
    DOI: 10.4103/1673-5374.295327
  • Vogel JK., Wegner M.:
    Astroglial changes induced by Gfap-dependent expression of a Sox9 transgene
    In: GLIA, HOBOKEN: 2021
  • Wittmann MT., Katada S., Sock E., Kirchner P., Ekici AB., Wegner M., Nakashima K., Lie DC., Reis A.:
    scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse
    In: Development 148 (2021), Art.Nr.: dev196022
    ISSN: 1477-9129
    DOI: 10.1242/DEV.196022
  • Wüst H., Wegener A., Fröb F., Hartwig A., Wegwitz F., Kari VL., Schimmel M., Tamm ER., Johnsen SA., Wegner M., Sock E.:
    H2B monoubiquitination is essential for peripheral myelination and guided by Egr2 in Schwann cells
    In: GLIA, HOBOKEN: 2021

  • Aprato J., Sock E., Weider M., Elsesser O., Fröb F., Wegner M.:
    Myrf guides target gene selection of transcription factor Sox10 during oligodendroglial development
    In: Nucleic Acids Research 48 (2020), S. 1254-1270
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkz1158
  • Hauberg ME., Creus-Muncunill J., Bendl J., Kozlenkov A., Zeng B., Corwin C., Chowdhury S., Kranz H., Hurd YL., Wegner M., Børglum AD., Dracheva S., Ehrlich ME., Fullard JF., Roussos P.:
    Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons
    In: Nature Communications 11 (2020), Art.Nr.: 5581
    ISSN: 2041-1723
    DOI: 10.1038/s41467-020-19319-2
  • Kozlenkov A., Vermunt MW., Apontes P., Li J., Hao K., Sherwood CC., Hof PR., Ely JJ., Wegner M., Mukamel EA., Creyghton MP., Koonin EV., Dracheva S.:
    Evolution of regulatory signatures in primate cortical neurons at cell-type resolution
    In: Proceedings of the National Academy of Sciences of the United States of America 117 (2020), S. 28422-28432
    ISSN: 0027-8424
    DOI: 10.1073/pnas.2011884117
  • Mertelmeyer S., Weider M., Baroti T., Reiprich S., Fröb F., Stolt C., Wagner KU., Wegner M.:
    The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland
    In: Scientific Reports 10 (2020), Art.Nr.: 17807
    ISSN: 2045-2322
    DOI: 10.1038/s41598-020-74664-y
  • Sagar ., Pokrovskii M., Herman JS., Naik S., Sock E., Zeis P., Lausch U., Wegner M., Tanriver Y., Littman DR., Gruen D.:
    Deciphering the regulatory landscape of fetal and adult gamma delta T-cell development at single-cell resolution
    In: EMBO Journal 39 (2020)
    ISSN: 0261-4189
    DOI: 10.15252/embj.2019104159
  • Sagar ., Pokrovskii M., Herman JS., Naik S., Sock E., Zeis P., Lausch U., Wegner M., Tanriver Y., Littman DR., Grün D.:
    Deciphering the regulatory landscape of fetal and adult γδ T-cell development at single-cell resolution
    In: EMBO Journal (2020)
    ISSN: 0261-4189
    DOI: 10.15252/embj.2019104159
  • Wang J., Wang J., Yang L., Zhao C., Wu LN., Xu L., Zhang F., Weng Q., Wegner M., Lu QR.:
    CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair
    In: Nature Communications 11 (2020), Art.Nr.: 4133
    ISSN: 2041-1723
    DOI: 10.1038/s41467-020-17955-2
  • Wedel M., Fröb F., Elsesser O., Wittmann MT., Lie DC., Reis A., Wegner M.:
    Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation
    In: Nucleic Acids Research 48 (2020), S. 4839-4857
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkaa218
  • Wegner M.:
    Specification of oligodendrocytes
    Elsevier, 2020
    ISBN: 9780128144053
    DOI: 10.1016/B978-0-12-814405-3.00034-5
  • Weider M., Schröder A., Docheva D., Rodrian G., Enderle I., Seidel CL., Andreev D., Wegner M., Bozec A., Deschner J., Kirschneck C., Proff P., Gölz L.:
    A human periodontal ligament fibroblast cell line as a new model to study periodontal stress
    In: International Journal of Molecular Sciences 21 (2020), S. 1-10
    ISSN: 1422-0067
    DOI: 10.3390/ijms21217961
  • Wittstatt J., Weider M., Wegner M., Reiprich S.:
    MicroRNA miR-204 regulates proliferation and differentiation of oligodendroglia in culture
    In: Glia (2020)
    ISSN: 0894-1491
    DOI: 10.1002/glia.23821
  • Wüst H., Wegener A., Fröb F., Hartwig A., Wegwitz F., Kari V., Schimmel M., Tamm ER., Johnsen SA., Wegner M., Sock E.:
    Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination
    In: Nucleic Acids Research 48 (2020), S. 8959-8976
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkaa606

  • Aprato J., Küspert M., Weider M., Fröb F., Wegner M.:
    Myrf as a molecular switch for target gene selection of Sox10 during oligodendroglial development
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Cantone M., Küspert M., Reiprich S., Lai X., Eberhardt M., Göttle P., Beyer F., Azim K., Küry P., Wegner M., Vera J.:
    A gene regulatory architecture that controls region-independent dynamics of oligodendrocyte differentiation
    In: Glia (2019)
    ISSN: 0894-1491
    DOI: 10.1002/glia.23569
  • Elsesser O., Fröb F., Küspert M., Tamm ER., Fujii T., Fukunaga R., Wegner M.:
    Chromatin remodeler Ep400 ensures oligodendrocyte survival and is required for myelination in the vertebrate central nervous system
    In: Nucleic Acids Research 47 (2019), S. 6208-6224
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkz376
  • Elsesser O., Wegner M.:
    Influence of chromatin remodeler Ep400 on oligodendroglial development
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Fröb F., Sock E., Tamm ER., Saur AL., Hillgärtner S., Williams TJ., Fujii T., Fukunaga R., Wegner M.:
    Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy
    In: Nature Communications 10 (2019)
    ISSN: 2041-1723
    DOI: 10.1038/s41467-019-10287-w
  • Fröb F., Sock E., Wegner M.:
    The influence of Ep400 on Schwann cell development in mice
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Fröb F., Wegner M.:
    The role of chromatin remodeling complexes in Schwann cell development
    In: Glia (2019)
    ISSN: 0894-1491
    DOI: 10.1002/glia.23766
  • Küspert M., Reiprich S., Cantone M., Weider M., Baroti T., Wittstatt J., Vera J., Wegner M.:
    Transcription factor Sox10 induces the microRNAs miR-335, miR-338 and miR-155 to ensure correct timing of oligodendrocyte development
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Sock E., Wegner M.:
    Transcriptional control of myelination and remyelination
    In: Glia (2019)
    ISSN: 0894-1491
    DOI: 10.1002/glia.23636
  • Vogel J., Weider M., Engler L., Hillgärtner S., Schmitt C., Hermans-Borgmeyer I., Wegner M.:
    Sox9 overexpression exerts multiple stage-dependent effects on mouse spinal cord development
    In: Glia (2019)
    ISSN: 0894-1491
    DOI: 10.1002/glia.23752
  • Vogel J., Weider M., Wegner M.:
    Sox9-overexpression promotes gliogenesis at the expense of neurogenesis in the embryonic mouse spinal cord
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Wedel M., Wegner M.:
    The role of Tcf4 in oligodendrocyte development
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Wegner M.:
    Transcriptional control in myelinating glia: from extrinsic signals to intrinsic factors and networks
    ISN-ASN Meeting (Montreal, 4. August 2019 - 8. August 2019)
    In: JOURNAL OF NEUROCHEMISTRY, HOBOKEN: 2019
  • Wittstatt J., Weider M., Reiprich S., Wegner M.:
    Impact of the microRNA family miR-204/-211 on the oligodendroglial gene regulatory network
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019
  • Wüst H., Wegener A., Johnson S., Fröb F., Wegner M., Sock E.:
    Epigenetic regulation in myelinating glia: the role of histone 2b monoubiquitination in Schwann cells
    14th European Meeting on Glial Cells in Health and Disease (GLIA) (Porto, 10. Juli 2019 - 13. Juli 2019)
    In: GLIA, HOBOKEN: 2019

  • Hoffmann A., Ettle B., Battis K., Reiprich S., Schlachetzki J., Masliah E., Wegner M., Kuhlmann T., Riemenschneider MJ., Winkler J.:
    Oligodendroglial α-synucleinopathy-driven neuroinflammation in multiple system atrophy
    In: Brain Pathology (2018)
    ISSN: 1015-6305
    DOI: 10.1111/bpa.12678
  • Jacob A., Wüst H., Thalhammer J., Fröb F., Küspert M., Reiprich S., Balta EA., Lie DC., Wegner M., Sock E.:
    The transcription factor prospero homeobox protein 1 is a direct target of SoxC proteins during developmental vertebrate neurogenesis
    In: Journal of Neurochemistry 146 (2018), S. 251-268
    ISSN: 0022-3042
    DOI: 10.1111/jnc.14456
  • Kozlenkov A., Li J., Apontes P., Hurd YL., Byne WM., Koonin E., Wegner M., Mukamel EA., Dracheva S.:
    A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons
    In: Science Advances 4 (2018)
    ISSN: 2375-2548
    DOI: 10.1126/sciadv.aau6190
  • Menzel-Severing J., Zenkel M., Polisetti N., Sock E., Wegner M., Kruse F., Schlötzer-Schrehardt U.:
    Transcription factor profiling identifies Sox9 as regulator of proliferation and differentiation in corneal epithelial stem/progenitor cells
    In: Scientific Reports 8 (2018)
    ISSN: 2045-2322
    DOI: 10.1038/s41598-018-28596-3
  • Neirijnck Y., Reginensi A., Renkema KY., Massa F., Kozlov VM., Dhib H., Bongers EMHF., Feitz WF., Van Eerde AM., Lefebvre V., Knoers NVAM., Tabatabaei M., Schulz H., Mcneill H., Schaefer F., Wegner M., Sock E., Schedl A.:
    Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).
    In: Kidney International 93 (2018), S. 1142-1153
    ISSN: 0085-2538
    DOI: 10.1016/j.kint.2017.11.026
  • Parfejevs V., Debbache J., Shakhova O., Schaefer SM., Glausch M., Wegner M., Suter U., Riekstina U., Werner S., Sommer L.:
    Injury-activated glial cells promote wound healing of the adult skin in mice.
    In: Nature Communications 9 (2018), S. 236
    ISSN: 2041-1723
    DOI: 10.1038/s41467-017-01488-2
  • Prochnicki A., Amann KU., Wegner M., Sock E., Pfister E., Shankland S., Pippin J., Daniel C.:
    Characterization of Glomerular Sox9+ Cells in Anti-Glomerular Basement Membrane Nephritis in the Rat
    In: American Journal of Pathology 188 (2018), S. 2529-2541
    ISSN: 0002-9440
    DOI: 10.1016/j.ajpath.2018.07.023
  • Rich CA., Perera SN., Andratschke J., Stolt C., Buehler DP., Southard-Smith EM., Wegner M., Britsch S., Baker CVH.:
    Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting
    In: Glia 66 (2018), S. 2617-2631
    ISSN: 0894-1491
    DOI: 10.1002/glia.23515
  • Truch K., Arter J., Turnescu T., Weider M., Hartwig A., Tamm ER., Sock E., Wegner M.:
    Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease.
    In: Human Molecular Genetics 27 (2018), S. 1078-1092
    ISSN: 0964-6906
    DOI: 10.1093/hmg/ddy029
  • Turnescu T., Arter J., Reiprich S., Tamm ER., Reiprich S., Waisman A., Wegner M.:
    Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes.
    In: Glia 66 (2018), S. 279-294
    ISSN: 0894-1491
    DOI: 10.1002/glia.23242
  • Weider M., Starost LJ., Groll K., Küspert M., Sock E., Wedel M., Fröb F., Schmitt C., Baroti T., Hartwig A., Hillgärtner S., Piefke S., Fadler T., Ehrlich M., Ehlert C., Stehling M., Albrecht S., Jabali A., Schoeler HR., Winkler J., Kuhlmann T., Wegner M.:
    Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.
    In: Nature Communications 9 (2018), S. 899
    ISSN: 2041-1723
    DOI: 10.1038/s41467-018-03336-3
  • Weider M., Starost LJ., Groll K., Küspert M., Sock E., Wedel M., Fröb F., Schmitt C., Baroti T., Hartwig A., Hillgärtner S., Piefke S., Fadler T., Ehrlich M., Ehlert C., Stehling M., Albrecht S., Jabali A., Schoeler HR., Winkler J., Kuhlmann T., Wegner M.:
    Publisher Correction: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning
    In: Nature Communications 9 (2018)
    ISSN: 2041-1723
    DOI: 10.1038/s41467-018-03871-z
  • Wüst H., Wegner M.:
    Oncogenic insult to the brain: Sox proteins rise to the occasion.
    In: TRANSLATIONAL CANCER RESEARCH 7 (2018), S. S31-S33
    ISSN: 2218-676X
    DOI: 10.21037/tcr.2017.12.19

  • Cantone M., Eberhardt M., Küspert M., Reiprich S., Wegner M., Vera J.:
    A web tool for the oligodendrocyte differentiation data and network analysis
  • Duncan GJ., Plemel JR., Assinck P., Manesh SB., Muir FGW., Hirata R., Berson M., Liu J., Wegner M., Emery B., Moore GRW., Tetzlaff W.:
    Myelin Regulatory Factor 1 Drives Remyelination in Multiple Sclerosis.
    In: Acta Neuropathologica (2017), S. 403-422
    ISSN: 0001-6322
    DOI: 10.1007/s00401-017-1741-7
  • Küspert M., Sock E., Wegner M.:
    The role of zinc finger transcription factor Zfp276 during glial development
  • Marathe HG., Watkins-Chow DE., Weider M., Hoffmann A., Trivedi A., Aras S., Mehta G., Basuroy T., Mehrotra A., Bennett DC., Wegner M., Pavan WJ., De La Serna IL.:
    BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation.
    In: Nucleic Acids Research 45 (2017), S. 6442-6458
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkx259
  • Mehta P., Küspert M., Bale T., Brownstein CA., Towne MC., De Girolami U., Shi J., Beggs AH., Darras BT., Wegner M., Piao X., Agrawal PB.:
    Novel mutation in CNTNAP1 results in congenital hypomyelinating neuropathy.
    In: Muscle & Nerve (2017), S. 761-765
    ISSN: 0148-639X
    DOI: 10.1002/mus.25416
  • Reiprich S., Cantone M., Weider M., Baroti T., Wittstatt J., Schmitt C., Küspert M., Vera J., Wegner M.:
    Transcription factor Sox10 regulates oligodendroglial Sox9 levels via microRNAs.
    In: Glia 65 (2017), S. 1089-1102
    ISSN: 0894-1491
    DOI: 10.1002/glia.23146
  • Wegener A., Küspert M., Sock E., Philipsen S., Suske G., Wegner M.:
    Sp2 is the only glutamine-rich Specificity protein with minor impact on development and differentiation in myelinating glia.
    In: Journal of Neurochemistry 140 (2017), S. 245-256
    ISSN: 0022-3042
    DOI: 10.1111/jnc.13908
  • Weider M., Schmitt C., Hillgärtner S., Wegner M.:
    Nkx2.2 is a direct target gene of Sox10 in oligodendroglia
  • Weider M., Wegner M.:
    SoxE factors: Transcriptional regulators of neural differentiation and nervous system development.
    In: Seminars in Cell & Developmental Biology (2017), S. 35-42.
    ISSN: 1084-9521
    DOI: 10.1016/j.semcdb.2016.08.013

  • Baroti T., Schillinger A., Wegner M., Stolt C.:
    Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes
    In: Journal of Neurochemistry 136 (2016), S. 316-28
    ISSN: 0022-3042
    DOI: 10.1111/jnc.13414
  • Baroti T., Zimmermann Y., Schillinger A., Liu L., Lommes P., Wegner M., Stolt C.:
    Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain
    In: Glia 64 (2016), S. 122-38
    ISSN: 0894-1491
    DOI: 10.1002/glia.22919
  • Ettle B., Kerman BE., Valera E., Gillmann C., Schlachetzki J., Reiprich S., Büttner C., Ekici AB., Reis A., Wegner M., Bäuerle T., Riemenschneider MJ., Masliah E., Gage FH., Winkler J.:
    ?-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy
    In: Acta Neuropathologica 132 (2016), S. 59-75
    ISSN: 0001-6322
    DOI: 10.1007/s00401-016-1572-y
  • Kozlenkov A., Wang M., Roussos P., Rudchenko S., Barbu M., Bibikova M., Klotzle B., Dwork AJ., Zhang B., Hurd YL., Koonin EV., Wegner M., Dracheva S.:
    Substantial DNA methylation differences between two major neuronal subtypes in human brain
    In: Nucleic Acids Research 44 (2016), S. 2593-612
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkv1304
  • Küspert M., Wegner M.:
    SomethiNG 2 talk about-Transcriptional regulation in embryonic and adult oligodendrocyte precursors
    In: Brain Research 1638 (2016), S. 167-82
    ISSN: 0006-8993
    DOI: 10.1016/j.brainres.2015.07.024
  • Muth K., Piefke S., Weider M., Sock E., Hermans-Borgmeyer I., Wegner M., Küspert M.:
    The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes
    In: Glia 64 (2016), S. 2120-2132
    ISSN: 0894-1491
    DOI: 10.1002/glia.23044
  • Quintes S., Brinkmann BG., Ebert M., Fröb F., Kungl T., Arlt FA., Tarabykin V., Huylebroeck D., Meijer D., Suter U., Wegner M., Sereda MW., Nave KA.:
    Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair
    In: Nature Neuroscience 19 (2016), S. 1050-9
    ISSN: 1097-6256
    DOI: 10.1038/nn.4321
  • Stolt C., Wegner M.:
    Schwann cells and their transcriptional network: Evolution of key regulators of peripheral myelination
    In: Brain Research 1641 (2016), S. 101-10
    ISSN: 0006-8993
    DOI: 10.1016/j.brainres.2015.09.025
  • Moyon S., Huynh J.L, Dutta D., Zhang F., Ma D., Yoo S., Lawrence R., Wegner Michael, John G.R., Emery B., Lubetzki C., Franklin R.J.M., Fan G., Zhu J., Dupree J.L, Casaccia P.:
    Functional characterization of DNA methylation in the oligodendrocyte lineage.
    In: Cell Reports (2016), S. 748-760
    ISSN: 2211-1247
    DOI: 10.1016/j.celrep.2016.03.060

  • Amaya DA., Wegner M., Stolt C., Chehrehasa F., Ekberg JAK., St John JA.:
    Radial glia phagocytose axonal debris from degenerating overextending axons in the developing olfactory bulb
    In: Journal of Comparative Neurology 523 (2015), S. 183-96
    ISSN: 0021-9967
    DOI: 10.1002/cne.23665
  • Anderson SR., Lee I., Ebeling C., Stephenson DA., Schweitzer KM., Baxter D., Moon TM., Lapierre S., Jaques B., Silvius D., Wegner M., Hood LE., Carlson G., Gunn TM.:
    Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice
    In: Mammalian Genome 26 (2015), S. 80-93
    ISSN: 0938-8990
    DOI: 10.1007/s00335-014-9548-5
  • Arter J., Wegner M.:
    Transcription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells
    In: Journal of Neurochemistry 132 (2015), S. 384-93
    ISSN: 0022-3042
    DOI: 10.1111/jnc.13013
  • Bischof M., Weider M., Küspert M., Nave KA., Wegner M.:
    Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation
    In: The Journal of Neuroscience 35 (2015), S. 21-35
    ISSN: 1529-2401
    DOI: 10.1523/JNEUROSCI.1468-14.2015
  • Kim GJ., Sock E., Buchberger A., Just W., Denzer F., Hoepffner W., German J., Cole T., Mann J., Seguin JH., Zipf W., Costigan C., Schmiady H., Rostasy M., Kramer M., Kaltenbach S., Roesler B., Georg I., Troppmann E., Teichmann AC., Salfelder A., Widholz SA., Wieacker P., Hiort O., Camerino G., Radi O., Wegner M., Arnold HH., Scherer G.:
    Copy number variation of two separate regulatory regions upstream of SOX9 causes isolated 46,XY or 46,XX disorder of sex development
    In: Journal of Medical Genetics 52 (2015), S. 240-7
    ISSN: 0022-2593
    DOI: 10.1136/jmedgenet-2014-102864
  • Lang H., Xing Y., Brown LN., Samuvel DJ., Panganiban CH., Havens LT., Balasubramanian S., Wegner M., Krug EL., Barth JL.:
    Neural stem/progenitor cell properties of glial cells in the adult mouse auditory nerve
    In: Scientific Reports 5 (2015), S. 13383
    ISSN: 2045-2322
    DOI: 10.1038/srep13383
  • Quiroga AC., Stolt C., Diez Del Corral R., Dimitrov S., Perez-Alcala S., Sock E., Barbas JA., Wegner M., Morales AV.:
    Sox5 controls dorsal progenitor and interneuron specification in the spinal cord
    In: Developmental Neurobiology 75 (2015), S. 522-38
    ISSN: 1932-8451
    DOI: 10.1002/dneu.22240
  • Reiprich S., Wegner M.:
    From CNS stem cells to neurons and glia: Sox for everyone
    In: Cell and Tissue Research 359 (2015), S. 111-24
    ISSN: 0302-766X
    DOI: 10.1007/s00441-014-1909-6
  • Shakhova O., Cheng P., Mishra PJ., Zingg D., Schaefer SM., Debbache J., Haeusel J., Matter C., Guo T., Davis S., Meltzer P., Mihic-Probst D., Moch H., Wegner M., Merlino G., Levesque MP., Dummer R., Santoro R., Cinelli P., Sommer L.:
    Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma
    In: PLoS Genetics 11 (2015), S. e1004877
    ISSN: 1553-7390
    DOI: 10.1371/journal.pgen.1004877
  • Wegener A., Deboux C., Bachelin C., Frah M., Kerninon C., Seilhean D., Weider M., Wegner M., Nait-Oumesmar B.:
    Gain of Olig2 function in oligodendrocyte progenitors promotes remyelination
    In: Brain 138 (2015), S. 120-35
    ISSN: 0006-8950
    DOI: 10.1093/brain/awu375
  • Weider M., Wegener A., Schmitt-Engel C., Küspert M., Hillgaertner S., Boesl MR., Hermans-Borgmeyer I., Nait-Oumesmar B., Wegner M.:
    Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells
    In: PLoS Genetics 11 (2015), S. e1005008
    ISSN: 1553-7390
    DOI: 10.1371/journal.pgen.1005008

  • Ettle B., Reiprich S., Deußer J., Schlachetzki J., Xiang W., Prots I., Masliah E., Winner B., Wegner M., Winkler J.:
    Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells
    In: Molecular and Cellular Neuroscience 62 (2014), S. 68-78
    ISSN: 1044-7431
    DOI: 10.1016/j.mcn.2014.06.012
  • Glasgow SM., Zhu W., Stolt C., Huang TW., Chen F., Loturco JJ., Neul JL., Wegner M., Mohila C., Deneen B.:
    Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes
    In: Nature Neuroscience 17 (2014), S. 1322-9
    ISSN: 1097-6256
    DOI: 10.1038/nn.3790
  • Hoffmann SA., Hos D., Küspert M., Lang RA., Lovell-Badge R., Wegner M., Reiprich S.:
    Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes
    In: Development 141 (2014), S. 39-50
    ISSN: 1477-9129
    DOI: 10.1242/dev.098418
  • May VEL., Ettle B., Pöhler AM., Nuber S., Ubhi K., Rockenstein E., Winner B., Wegner M., Masliah E., Winkler J.:
    ?-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy
    In: Neurobiology of Aging 35 (2014), S. 2357-68
    ISSN: 0197-4580
    DOI: 10.1016/j.neurobiolaging.2014.02.028
  • Paul M., Harvey RP., Wegner M., Sock E.:
    Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types
    In: Cellular and Molecular Life Sciences 71 (2014), S. 2931-45
    ISSN: 1420-682X
    DOI: 10.1007/s00018-013-1523-x
  • Reiprich S., Wegner M.:
    Sox2: A multitasking networker.
    In: Neurogenesis (2014), S. e962391
    ISSN: 2326-2133
  • Mao Y.Y., Reiprich Simone, Wegner Michael, Fritzsch B.:
    Targeted deletion of Sox10 by Wnt1-cre defects: neuronal migration and projection in the mouse inner ear.
    In: PLoS ONE (2014), S. e94580
    ISSN: 1932-6203
  • Glasgow S., Zhu W, Stolt C.C., Huang T.-E., Chen F., LoTurco J.J., Neul J.L., Wegner Michael, Mohila C., Deneen B.:
    Mutual Antagonism Between Sox10 and NFIA Regulates Diversification of Glial Lineages and Glioma Sub-Types.
    In: Nature Neuroscience (2014), S. 1322-1329
    ISSN: 1097-6256
  • Winner B., May VEL., Ettle B., Pöhler AM., Nuber S., Ubhi K., Rockenstein E., Wegner M., Masliah E., Winkler J.:
    α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy.
    In: Neurobiology of Aging 35 (2014), S. 2357-68
    ISSN: 0197-4580
    DOI: 10.1016/j.neurobiolaging.2014.02.028
  • Zhu Q., Zhao X., Zheng K., Li H., Huang H., Zhang Z., Mastracci T., Wegner M., Chen Y., Sussel L., Qiu M.:
    Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS
    In: Development 141 (2014), S. 548-55
    ISSN: 1477-9129
    DOI: 10.1242/dev.095323

  • Barraud P., St John JA., Stolt C., Wegner M., Baker CVH.:
    Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons
    In: Biology Open 2 (2013), S. 750-9
    ISSN: 2046-6390
    DOI: 10.1242/bio.20135249
  • Bujalka H., Koenning M., Jackson S., Perreau VM., Pope B., Hay CM., Mitew S., Hill AF., Lu QR., Wegner M., Srinivasan R., Svaren J., Willingham M., Barres BA., Emery B.:
    MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes
    In: Plos Biology 11 (2013), S. e1001625
    ISSN: 1544-9173
    DOI: 10.1371/journal.pbio.1001625
  • Harris ML., Buac K., Shakhova O., Hakami RM., Wegner M., Sommer L., Pavan WJ.:
    A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors
    In: PLoS Genetics 9 (2013), S. e1003644
    ISSN: 1553-7390
    DOI: 10.1371/journal.pgen.1003644
  • Hornig J., Fröb F., Vogl M., Hermans-Borgmeyer I., Tamm ER., Wegner M.:
    The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes
    In: PLoS Genetics 9 (2013), S. e1003907
    ISSN: 1553-7390
    DOI: 10.1371/journal.pgen.1003907
  • Usui A., Mochizuki Y., Iida A., Miyauchi E., Satoh S., Sock Elisabeth, Nakauchi H., Aburatani H., Murakami A., Wegner Michael, Watanabe S.:
    The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells.
    In: Development (2013), S. 740-750
    ISSN: 1477-9129
    DOI: 10.1242/dev.090274
  • Trost A., Schroedl F., Lange S., Rivera FJ., Tempfer H., Korntner S., Stolt C., Wegner M., Bogner B., Kaser-Eichberger A., Krefft K., Runge C., Aigner L., Reitsamer HA.:
    Neural crest origin of retinal and choroidal pericytes
    In: Investigative Ophthalmology & Visual Science 54 (2013), S. 7910-21
    ISSN: 0146-0404
    DOI: 10.1167/iovs.13-12946
  • Vogl M., Reiprich S., Küspert M., Kosian T., Schrewe H., Nave KA., Wegner M.:
    Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia
    In: The Journal of Neuroscience 33 (2013), S. 6679-90
    ISSN: 1529-2401
    DOI: 10.1523/JNEUROSCI.5178-12.2013
  • Usui A., Iwagawa T., Mochizuki Y., Iida A., Wegner Michael, Murakami A., Watanabe S.:
    Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development.
    In: Febs Letters (2013), S. 358-363
    ISSN: 0014-5793
    DOI: 10.1016/j.febslet.2012.12.017
  • Wegner M.:
    Mighty bugs: leprosy bacteria turn schwann cells into stem cells.
    In: Cell (2013), S. 15-16
    ISSN: 0092-8674
    DOI: 10.1016/j.cell.2013.01.001
  • Doddrell R.D., Dun X.P., Shivane A., Feltri M.L., Wrabetz L., Wegner Michael, Sock Elisabeth, Hanemann C.O., Parkinson D.B.:
    Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells.
    In: Brain (2013), S. 549-563
    ISSN: 0006-8950
    DOI: 10.1093/brain/aws353
  • Weider M., Reiprich S., Wegner M.:
    Sox appeal - Sox10 attracts epigenetic and transcriptional regulators in myelinating glia
    In: Biological Chemistry 394 (2013), S. 1583-93
    ISSN: 1431-6730
    DOI: 10.1515/hsz-2013-0146

  • Fröb Franziska, Bremer M., Finzsch M., Kichko Tetyana, Reeh Peter W., Tamm E.R., Charnay P., Wegner Michael:
    Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10.
    In: Glia (2012), S. 806-819
    ISSN: 0894-1491
    DOI: 10.1002/glia.22310
  • Küspert Melanie, Weider Matthias, Müller Jana, Hermans-Borgmeyer I., Meijer D., Wegner Michael:
    Desert Hedgehog links transcription factor Sox10 to perineurial development.
    In: Journal of Neuroscience (2012), S. 5472-5480
    ISSN: 0270-6474
    DOI: 10.1523/jneurosci.5759-11.2012
  • Wahlbuhl M., Reiprich Simone, Vogl M.R., Bösl M.R., Wegner Michael:
    Transcription factor Sox10 orchestrates activity of a neural crest-specific enhancer in the vicinity of its gene.
    In: Nucleic Acids Research (2012), S. 88-101
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkr734
  • Shakhova O., Zingg D., Schaefer S.M., Hari L., Civenni G., Blunschi J., Claudinot S., Okoniewski M., Beermann F., Mihic-Probst D., Moch H., Wegner Michael, Dummer R., Barrandon Y., Cinelli P., Sommer L.:
    Sox10 promotes the formation and maintenance of giant congenital nevus and melanoma.
    In: Nature Cell Biology (2012), S. 882-890
    ISSN: 1465-7392
  • Yusuf D., Butland S.I., Swanson M.I., Bolotin E., Ticoll A., Cheung W.A., Zhang X.Y., Dickman C.T., Fulton D.L., Lim J.S., Schnabl J.M., Ramos O.H., Vasseur-Cognet M., de Leeuw C.N., Simpson E.M., Ryffel G.U., Lam E.W., Kist R., Wilson M.S., Marco-Ferreres R., Brosens J.J., Beccari L.L., Bovolenta P., Benayoun B.A., Monteiro L.J., Schwenen H.D., Grontved L., Wederell E., Mandrup S., Veitia R.A., Chakravarthy H., Hoodless P.A., Mancarelli M., Torbett B.E., Banham A.H., Reddy S.P., Cullum R.L., Liedtke M., Tschan M.P., Vaz M., Rizzino A., Zannini M., Frietze S., Farnham P.J., Eijkelenboom A., Brown P.J., Laperriere D., Leprince D., de Cristofaro T., Prince K.L., Putker M., Del Peso L., Camenich G., Wenger R.H., Mikula M., Rozendaal M., Mader S., Ostrowski J., Rhodes S.J., Van Rechem C., Boulay G., Olechnowicz S.W., Breslin M.B., Lan M.S., Nanan K.K., Wegner Michael, Hou J., Mullen R.D., Colvin S.C., Noy P.J., Webb C.F., Witek M.E., Ferrell S., Daniel J.M., Park J., Waldman S.A., Peet D.J., Taggart M., Jayaraman P.S., Karrich J.J., Blom B., Vesuna F., O´Green H., Sun Y., Gronostajski R.M., Woodcroft M.W., Hough M.R., Chen E., Europe-Finner N., Karolczak-Bayatti M., Bailey J., Hankinson O., Raman V., Lebrun D.P., Biswal S., Harvey C.J., Debruyne J.P., Hogenesch J.B., Hevner R.F., Heligon C., Luo X.M., Blank M.C., Millen K.J., Sharlin D.S., Forrest D., Dahlman-Wright K., Zhao C., Mishima Y., Sinha S., Chakrabarti R., Portales-Casamar E., Sladek F.M., Bradley P.H., Wasserman W.W.:
    The Transcription Factor Encyclopedia.
    In: Genome Biology (2012), S. R24
    ISSN: 1474-7596
    DOI: 10.1186/gb-2012-13-3-r24
  • Mu L., Berti L., Masserdotti G., Covic M., Michaelidis T., Doberauer K., Merz K., Rehfeld F., Haslinger A., Wegner Michael, Sock Elisabeth, Lefebvre V., Couillard-Depres S., Aigner L., Berninger B., Lie Dieter Chichung:
    SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.
    In: Journal of Neuroscience (2012), S. 3067-3080
    ISSN: 0270-6474
    DOI: 10.1523/JNEUROSCI.4679-11.2012
  • Weider Matthias, Küspert Melanie, Bischof Melanie, Vogl M.R., Hornig Julia, Loy Kristina, Kosian T., Müller Jana, Hillgärtner Simone, Tamm E.R., Metzger D. , Wegner Michael:
    Chromatin remodelling factor Brg1 is required for Schwann cell differentiation and myelination.
    In: Developmental Cell (2012), S. 193-201
    ISSN: 1534-5807
    DOI: 10.1016/j.devcel.2012.05.017

  • Bremer M., Fröb Franziska, Kichko Tetyana, Reeh Peter W., Tamm E.R., Suter U., Wegner Michael:
    Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve.
    In: Glia (2011), S. 1022-1032
    ISSN: 0894-1491
    DOI: 10.1002/glia.21173
  • Küspert M., Hammer A., Bösl M., Wegner M.:
    Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer.
    In: Nucleic Acids Research (2011), S. 1280-1293
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkq951
  • Lin L., Lee V.M., Wang Y., Lin J.S., Sock Elisabeth, Wegner Michael, Lei L.:
    Sox11 regulates survival and axonal growth of embryonic sensory neurons.
    In: Developmental Dynamics (2011), S. 52-64
    ISSN: 1058-8388
    DOI: 10.1002/dvdy.22489
  • Reginensi A., Clarkson M., Neirijnck Y., Lu B., Ohyama T., Groves A.K., Sock Elisabeth, Wegner Michael, Costantini F., Chaboissier M.C., Schedl A.:
    SOX9 controls epithelial branching by activating RET effector genes during kidney development.
    In: Human Molecular Genetics (2011), S. 1143-1153
    ISSN: 0964-6906
    DOI: 10.1093/hmg/ddq558
  • Gallenberger M., Meinel D., Kroeber M., Wegner Michael, Milkereit P., Bösl M.R., Tamm E.R.:
    Lack of Wdr36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro.
    In: Human Molecular Genetics (2011), S. 422-435
    ISSN: 0964-6906
    DOI: 10.1093/hmg/ddq478
  • Wegner M.:
    SOX after SOX: SOXession regulates neurogenesis.
    In: Genes & Development (2011), S. 2423-24-28
    ISSN: 0890-9369
    DOI: 10.1101/gad.181487.111
  • John N., Cinelli P., Wegner Michael, Sommer L.:
    Transforming Growth Factor β-Mediated Sox10 Suppression Controls Mesenchymal Progenitor Generation in Neural Crest Stem Cells.
    In: Stem cells (2011), S. 689-699
    ISSN: 0250-6793
    DOI: 10.1002/stem.607

  • Thein D.C., Thalhammer J.M., Hartwig Anna, Crenshaw III E.B., Lefebvre V., Wegner Michael, Sock Elisabeth:
    The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development.
    In: Journal of neurochemistry (2010), S. 131-141
    ISSN: 1471-4159
    DOI: 10.1111/j.1471-4159.2010.06910.x
  • Cossais Francois, Wahlbuhl Mandy, Müller Jana, Wegner Michael:
    SOX10 structure function analysis in the chicken reveals important insights into its role in human neurocristopathies.
    In: Human Molecular Genetics (2010), S. 2409-2420
    ISSN: 0964-6906
  • Reiprich Simone, Müller Jana, Schreiner S., Wegner Michael:
    Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells.
    In: Journal of Neurochemistry (2010), S. 744-754
    ISSN: 0022-3042
    DOI: 10.1111/j.1471-4159.2009.06498.x
  • Guth S.I.E., Bösl M.R., Sock Elisabeth, Wegner Michael:
    Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene.
    In: International Journal of Biochemistry & Cell Biology (2010), S. 465-471
    ISSN: 1357-2725
    DOI: 10.1016/j.biocel.2009.07.008
  • Bhattaram P., Penzo-Mendez A., Sock Elisabeth, Colmenares C., Kaneko K.J., Vassilev A., DePamphilis M.L., Wegner Michael, Lefebvre V.:
    Organogenesis relies on Sox4, Sox11, and Sox12 for survival of neural and mesenchymal progenitor cells.
    In: Nature Communications (2010), S. 9
    ISSN: 2041-1723
  • Cossais Francois, Sock Elisabeth, Hornig J., Schreiner S., Kellerer S., Bösl M.R., Russel S., Wegner Michael:
    Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression.
    In: Developmental Biology (2010), S. 267-281
    ISSN: 0012-1606
    DOI: 10.1016/j.ydbio.2010.01.038
  • Breuskin I., Bodson M., Thelen N., Thiry M., Borgs L., Nguyen L., Stolt Claus, Wegner Michael, Lefebvre P.P., Malgrange B.:
    Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10.
    In: Journal of Neurochemistry (2010), S. 1827-1839
    ISSN: 0022-3042
    DOI: 10.1111/j.1471-4159.2010.06897.x
  • Stolt C., Wegner M.:
    SoxE function in vertebrate nervous system development.
    In: International Journal of Biochemistry & Cell Biology (2010), S. 437-440
    ISSN: 1357-2725
    DOI: 10.1016/j.biocel.2009.07.014
  • Wegner M.:
    All purpose SOX: The many roles of Sox proteins in gene expression.
    In: International Journal of Biochemistry & Cell Biology (2010), S. 381-390
    ISSN: 1357-2725
    DOI: 10.1016/j.biocel.2009.07.006
  • Staffler A., Hammel M., Wahlbuhl Mandy, Bidlingmaier C., Flemmer A.W., Pagel P., Nicolai T., Wegner Michael, Holzinger A.:
    Heterozygous SOX9 mutations allowing for residual DNA-binding and transcriptional activation lead to the acampomelic variant of Campomelic Dysplasia.
    In: Human Mutation (2010), S. E1436-1444
    ISSN: 1059-7794
    DOI: 10.1002/humu.21238
  • Kanykina N., Abelson K., King D., Liakhovitskaia A., Schreiner S., Wegner Michael, Kozlova E.N.:
    In vitro and in vivo effects on neural crest stem cell differentiation by conditional activation of Runx1 short isoform and its effect on neuropathic pain behaviour.
    In: Upsala Journal of Medical Sciences (2010), S. 56-64
    ISSN: 0300-9734
    DOI: 10.3109/03009730903572065
  • Wallace A., Schmidt C., Schachner M., Wegner Michael, Anderson R.:
    L1cam acts as a modifier gene during enteric nervous system development.
    In: Neurobiology of Disease (2010), S. 622-633
    ISSN: 0969-9961
    DOI: 10.1016/j.nbd.2010.08.006
  • Park J., Zhang J.J.R., Moro A., Kushida M., Wegner Michael, Kim P.C.W.:
    Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage.
    In: Developmental Dynamics (2010), S. 514-526
    ISSN: 1058-8388
    DOI: 10.1002/dvdy.22192
  • Finzsch M., Schreiner S., Kichko T., Reeh R., Tamm E.R., Bösl M.R., Meijer D., Wegner Michael:
    Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.
    In: The Journal of Cell Biology (2010), S. 701-712
    ISSN: 0021-9525
    DOI: 10.1083/jcb.200912142
  • Potzner M.R., Tsarovina K., Binder E., Penzo-Méndez A., Lefebvre V., Rohrer H., Wegner Michael, Sock Elisabeth:
    Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system.
    In: Development (2010), S. 775-784
    ISSN: 1477-9129
    DOI: 10.1242/dev.042101

  • Wolf M., Lommes P., Sock Elisabeth, Reiprich Simone, Friedrich R.P., Müller Jana, Stolt Claus, Bermingham J.R., Wegner Michael:
    Replacement of related POU transcription factors leads to severe defects in mouse forebrain development.
    In: Developmental Biology (2009), S. 418-428
    ISSN: 0012-1606
    DOI: 10.1016/j.ydbio.2009.06.011
  • Guth S.I.E., Schmidt K., Hess A., Wegner Michael:
    Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor.
    In: Journal of Lipid Research (2009), S. 1269-1280
    ISSN: 0022-2275
    DOI: 10.1194/jlr.M800531-JLR200
  • Aldskogius H., Berens C., Kanaykina N., Liakhovitskaia A., Medvinsky A., Sandelin M., Schreiner S., Wegner Michael, Hjerling-Leffler J., Kozlova E.N.:
    Regulation of Boundary Cap Neural Crest Stem Cell Differentiation after Transplantation.
    In: Stem cells (2009), S. 1592-1603
    ISSN: 0250-6793
    DOI: 10.1002/stem.77
  • Barrionuevo F., Georg I., Scherthan H., Lécureuil C., Guillou F., Wegner Michael, Scherer G.:
    Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8.
    In: Developmental Biology (2009), S. 301-312
    ISSN: 0012-1606
    DOI: 10.1016/j.ydbio.2008.12.011
  • Batista-Brito R., Rossignol E., Hjerling-Leffler J., Denaxa M., Wegner Michael, Lefebvre V., Pachnis V., Fishell G.:
    The cell-intrinsic requirement of Sox6 for cortical interneuron development.
    In: Neuron (2009), S. 466-481
    ISSN: 0896-6273
    DOI: 10.1016/j.neuron.2009.08.005

  • Reiprich Simone, Stolt Claus, Schreiner S., Parlato R., Wegner Michael:
    SoxE proteins are differentially required in mouse adrenal gland development.
    In: Molecular Biology of the Cell (2008), S. 1575-1586
    ISSN: 1059-1524
    DOI: 10.1091/mbc.E07-08-0782
  • Wurm A., Sock Elisabeth, Fuchshofer R., Wegner Michael, Tamm E.R.:
    Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11.
    In: Experimental Eye Research (2008), S. 895-907
    ISSN: 0014-4835
    DOI: 10.1016/j.exer.2008.03.004
  • Stolt Claus, Lommes P., Hillgärtner Simone, Wegner Michael:
    The transcription factor Sox5 modulates Sox10 function during melanocyte development.
    In: Nucleic Acids Research (2008), S. 5427-5440
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkn527
  • Müller S.M., Stolt Claus, Terszowski G., Blum C., Amagai T., Kessaris N., Iannarelli P., Richardson W.D., Wegner Michael, Rodewald H.R.:
    Neural crest origin of perivascular mesenchyme in the adult thymus.
    In: Journal of Immunology (2008), S. 5344-5351
    ISSN: 0022-1767
  • Finzsch Markus, Stolt Claus, Lommes P., Wegner Michael:
    Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression.
    In: Development (2008), S. 637-646
    ISSN: 1477-9129
    DOI: 10.1242/dev.010454
  • Wegner M.:
    A matter of identity: transcriptional control in oligodendrocytes.
    In: Journal of Molecular Neuroscience (2008), S. 3-12
    ISSN: 0895-8696
  • Aquino J.B., Marmigere F., Lallemend F., Lundgren T.K., Villar M.J., Wegner Michael, Ernfors P.:
    Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues.
    In: Gene Expression Patterns (2008), S. 217-226
    ISSN: 1567-133X
    DOI: 10.1016/j.gep.2008.01.001
  • Guth S.I.E., Wegner Michael:
    Having it both ways: Sox protein function between conservation and innovation.
    In: Cellular and Molecular Life Sciences (2008), S. 3000-3018
    ISSN: 1420-682X
    DOI: 10.1007/s00018-008-8138-7
  • Hoff S., Zeller F., Hann von Weyern C.W., Wegner Michael, Schemann M., Michel K., Rühl A.:
    Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody.
    In: Journal of Comparative Neurology (2008), S. 356-371
    ISSN: 0021-9967
    DOI: 10.1002/cne.21769
  • Wang H., Leav I., Ibaragi S., Wegner Michael, Hu G.F., Lu M., Balk S., Yuan X.:
    SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion.
    In: Cancer Research (2008), S. 1625-1630
    ISSN: 0008-5472
    DOI: 10.1158/0008-5472.CAN-07-5915
  • Hoser M., Potzner M.R., Koch J.M.C., Bösl M.R., Wegner Michael, Sock Elisabeth:
    Sox12 deletion in the mouse reveals non-reciprocal redundancy with the related Sox4 and Sox11 transcription factors.
    (2008), S. 4675-4687

  • Hoser M. , Baader S.L., Bösl M.R., Ihmer A., Wegner Michael, Sock Elisabeth:
    Prolonged glial expression of Sox4 in the central nervous system leads to architectural cerebellar defects and ataxia.
    In: The Journal of Neuroscience (2007), S. 5495-5505
    ISSN: 1529-2401
  • Schlierf B., Friedrich R.P., Felsberg J., Reifenberger G., Wegner Michael:
    Expression of SoxE and SoxD genes in human gliomas.
    In: Neuropathology and Applied Neurobiology (2007), S. 621-630
    ISSN: 0305-1846
    DOI: 10.1111/j.1365-2990.2007.00881.x
  • Liu Z., Hu X., Cai J., Liu B., Peng X., Wegner Michael, Qiu M.:
    Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.
    In: Developmental Biology (2007), S. 683-693
    ISSN: 0012-1606
    DOI: 10.1016/j.ydbio.2006.10.007
  • Werner T., Hammer A., Wahlbuhl Mandy, Bösl Michael, Wegner Michael:
    Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis.
    In: Nucleic Acids Research (2007), S. 6526-6538
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkm727
  • Inoue K., Ohyama T., Sakuragi Y., Li-Hua Y., Yamamoto R., Yu L.-H., Goto Y-i., Wegner Michael, Lupski J.R.:
    Translation of SOX10 3' untranslated region causes a complex severe neurocristopathy by generation of a deleterious functional domain.
    In: Human Molecular Genetics (2007), S. 3037-3046
    ISSN: 0964-6906
    DOI: 10.1093/hmg/ddm262
  • Schreiner S., Cossais Francois, Fischer K., Scholz S., Bösl Rebecca, Holtmann B., Sendtner M., Wegner Michael:
    Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages.
    In: Development (2007), S. 3271-3281
    ISSN: 1477-9129
    DOI: 10.1242/dev.003350

  • Stolt Claus, Schlierf A., Lommes Petra, Hillgärtner S., Werner T., Kosian T., Sock Elisabeth, Kessaris N., Richardson W.D., Lefebre V., Wegner Michael:
    SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.
    In: Developmental Cell (2006), S. 697-709
    ISSN: 1534-5807
    DOI: 10.1016/j.devcel.2006.08.011
  • Kessaris N., Fogarty M., Iannarelli P., Grist M., Wegner Michael, Richardson W.D.:
    Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an early embryonic lineage.
    In: Nature Neuroscience (2006), S. 173-179
    ISSN: 1097-6256
  • Ito Y., Wiese S., Chittka A., Rossol W., Bömmel H., Watabe K., Wegner Michael, Sendtner M.:
    Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells.
    In: Proceedings of the National Academy of Sciences of the United States of America (2006), S. 7871-7876
    ISSN: 0027-8424
    DOI: 10.1073/pnas.0602332103
  • Wißmüller S., Kosian T., Wolf Matthias, Wegner Michael:
    The High-mobility-group domain of Sox proteins interacts with the DNA-binding domains of many transcription factors.
    In: Nucleic Acids Research (2006), S. 1735-1744
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkl105
  • Marmigere F., Montelius A., Wegner Michael, Groner Y., Reichardt L.F., Ernfors P.:
    The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons.
    In: Nature Neuroscience (2006), S. 180-187
    ISSN: 1097-6256
    DOI: 10.1038/nn1631
  • Schlierf Beate, Werner T., Glaser Gabriele, Wegner Michael:
    Expression of Connexin47 in oligodendrocytes is regulated by the Sox10 transcription factor.
    In: Journal of Molecular Biology (2006), S. 11-21
    ISSN: 0022-2836
    DOI: 10.1016/j.jmb.2006.05.072
  • Bannykh S.I., Stolt Claus, Kim J., Perry A., Wegner Michael:
    Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas.
    In: Journal of Neuro-Oncology (2006), S. 115-127
    ISSN: 0167-594X
  • Kellerer S., Schreiner Silke, Stolt Claus, Scholz Sebastian, Bösl M.R., Wegner Michael:
    Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence.
    In: Development (2006), S. 2875-286
    ISSN: 1477-9129
    DOI: 10.1242/dev.02477

  • Schmidt K., Schinke T., Haberland M., Priemel M., Schilling A.F., Mueldner C., Rueger J.M., Sock Elisabeth, Wegner Michael, Amling M.:
    The high-mobility-group transcription factor Sox8 is a negative regulator of osteoblast differentiation.
    In: The Journal of Cell Biology (2005), S. 899-910
    ISSN: 0021-9525
    DOI: 10.1083/jcb.200408013
  • Baranek C., Sock Elisabeth, Wegner Michael:
    The POU protein Oct-6 is a nucleocytoplasmic shuttling protein.
    In: Nucleic Acids Research (2005), S. 6277-6286
    ISSN: 0305-1048
    DOI: 10.1093/nar/gki947
  • Stolt Claus, Schmitt S., Lommes Petra, Sock Elisabeth, Wegner Michael:
    Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord.
    In: Developmental Biology (2005), S. 309-317
    ISSN: 0012-1606
    DOI: 10.1016/j.ydbio.2005.03.010
  • Wegner M.:
    Secrets to a healthy Sox life: Lessons for melanocytes.
    In: Pigment Cell Research (2005), S. 74-85
    ISSN: 0893-5785
    DOI: 10.1111/j.1600-0749.2005.00218.x
  • Friedrich R.P., Schlierf Beate, Tamm E.R., Bösl M.R., Wegner Michael:
    The class III POU domain protein Brn-1 can fully replace the related Oct-6 during Schwann cell development and myelination.
    In: Molecular and Cellular Biology (2005), S. 1821-1829
    ISSN: 0270-7306
    DOI: 10.1128/MCB.25.5.1821-1829.2005
  • Schlierf Beate, Lang Stefan, Kosian T., Werner Thomas, Wegner Michael:
    The high-mobility group transcription factor Sox10 interacts with the N-myc interacting protein Nmi.
    In: Journal of Molecular Biology (2005), S. 1033-1042
    ISSN: 0022-2836
    DOI: 10.1016/j.jmb.2005.09.013
  • Thomee C., Schubert S.W., Parma J., Le P.Q., Hashemolhosseini Said, Wegner Michael, Abramowicz M.J.:
    GCMB mutation in familial isolated hypo-parathyroidism with residual secretion of parathyroid hormone.
    In: Journal of Clinical Endocrinology and Metabolism (2005), S. 2487-2492
    ISSN: 0021-972X
  • Wegner M., Stolt C.:
    From stem cells to neurons and glia: a soxist's view of neural development.
    In: Trends in Neurosciences (2005), S. 583-588
    ISSN: 0166-2236
    DOI: 10.1016/j.tins.2005.08.008
  • Maka Marzena, Stolt Claus, Wegner Michael:
    Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect.
    In: Developmental Biology (2005), S. 155-169
    ISSN: 0012-1606
    DOI: 10.1016/j.ydbio.2004.09.014

  • Sock Elisabeth, Rettig S.D., Enderich J., Bösl M.R., Tamm E.R., Wegner Michael:
    Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling.
    In: Molecular and Cellular Biology (2004), S. 6635-6644
    ISSN: 0270-7306
    DOI: 10.1128/MCB.24.15.6635-6644.2004
  • Ludwig Andreas, Schlierf Beate, Schardt A., Nave K.A., Wegner Michael:
    A Sox10 rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes.
    In: Genesis (2004), S. 171-175
    ISSN: 1526-954X
  • Chaboissier M.-C., Kobayashi A., Vidal V.I.P., Lützkendorf S., van de Kant H.J.G., Wegner Michael, de Rooij D.G., Behringer R.R., Schedl A.:
    Functional analysis of Sox8 and Sox9 during sex determination in the mouse.
    In: Development (2004), S. 1891-1901
    ISSN: 1477-9129
    DOI: 10.1242/dev.01087
  • Schubert S.W., Kardash E., Khan M.A., Cheusova T., Kilian K., Wegner Michael:
    Interaction, Cooperative Promoter Modulation and Renal Colocalisation of GCMa and Pitx2.
    In: Journal of Biological Chemistry (2004), S. 50358-50365
    ISSN: 0021-9258
  • Ludwig A., Rehberg S., Wegner Michael:
    Melanocyte-Specific Expression Of Dopachrome Tautomerase Is Dependent On Synergistic Gene Activation By The Sox10 And Mitf Transcription Factors.
    In: Febs Letters (2004), S. 236-244
    ISSN: 0014-5793
    DOI: 10.1016/S0014-5793(03)01446-7
  • Inoue K., Khajavi M., Ohyama T., Hirabayashi S.-I., Wilson J., Reggin J.D., Mancias P., Butler I.J., Wilkinson M.F., Wegner Michael, Lupski J.R.:
    Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations.
    In: Nature Genetics (2004), S. 361-369
    ISSN: 1061-4036
    DOI: 10.1038/ng1322
  • Hashemolhosseini Said, Schmidt K., Kilian K., Rodriguez E., Wegner Michael:
    Conservation and variation of structure and function in a newly identified GCM homolog from chicken
    In: Journal of Molecular Biology (2004), S. 441-451
    ISSN: 0022-2836
    DOI: 10.1016/j.jmb.2003.12.029
  • Wegner M., Hashemolhosseini S.:
    Impacts of a new trancription factor family: Mammalian GCM proteins in health and disease.
    In: The Journal of Cell Biology (2004), S. 765-768
    ISSN: 0021-9525
  • Stolt Claus, Lommes Petra, Friedrich R.P., Wegner Michael:
    Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy.
    In: Development (2004), S. 2349-2358
    ISSN: 1477-9129
    DOI: 10.1242/dev.01114

  • Sock Elisabeth, Pagon Roberta A., Keymolen Kathelijn, Lissens Willy, Wegner Michael, Scherer Gerd:
    Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia
    In: Human Molecular Genetics 12 (2003), S. 1439-1447
    ISSN: 0964-6906
  • Stolt Claus, Lommes Petra, Sock Elisabeth, Chaboissier M.-C., Schedl A., Wegner Michael:
    The Sox9 transcription factor determines glial fate choice in the developing spinal cord.
    In: Genes & Development (2003), S. 1677-1689
    ISSN: 0890-9369
    DOI: 10.1101/gad.259003
  • Huber W.E., Price R., Widlund H.R., Du J., Davis I.J., Wegner Michael, Fisher D.E.:
    A tissue restricted cAMP transcriptional response: SOX10 modulates MSH-triggered expression of MITF in melanocytes.
    In: Journal of Biological Chemistry (2003), S. 45224-45230
    ISSN: 0021-9258
  • Lioubinski O, Müller M, Wegner Michael, Sander Manfred:
    Expression of Sox transcription factors in the developing mouse pancreas.
    In: Developmental Dynamics (2003), S. 402-408
    ISSN: 1058-8388
    DOI: 10.1002/dvdy.10311
  • Schmidt Katy, Glaser Gabriele, Wernig Anton, Wegner Michael, Rosorius Olaf:
    Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis
    In: Journal of Biological Chemistry (2003), S. 29769-29775
    ISSN: 0021-9258
    DOI: 10.1074/jbc.M301539200
  • Cohen Serge X., Moulin Martine, Hashemolhosseini Said, Kilian Karin, Wegner Michael, Müller Christoph W.:
    Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition
    In: EMBO Journal 22 (2003), S. 1835-45
    ISSN: 0261-4189
    DOI: 10.1093/emboj/cdg182

  • Hashemolhosseini S., Hadjihannas M., Haase C., Amann KU., Wegner M.:
    Restricted expression of mGCMa in kidney ind thymus
    In: Mechanisms of Development (2002), S. in press
    ISSN: 0925-4773
  • Hashemolhosseini Said, Hadjihannas Michel, Stolt Claus, Haas Christian, Amann Kerstin U., Wegner Michael:
    Restricted expression of mouse GCMa/Gcm1 in kidney and thymus
    In: Mechanisms of Development 118 (2002), S. 175-178
    ISSN: 0925-4773
    DOI: 10.1016/S0925-4773(02)00239-3
  • Schlierf Beate, Ludwig Andreas, Klenovsek Karin, Wegner Michael:
    Cooperative binding of Sox10 to DNA: requirements and consequences
    In: Nucleic Acids Research 30 (2002), S. 5509-5516
    ISSN: 0305-1048
    DOI: 10.1093/nar/gkf690
  • Cohen Serge X., Moulin Martine, Schilling Oliver, Meyer-Klaucke Wolfram, Schreiber Jörg, Wegner Michael, Müller Christoph W.:
    The GCM domain is a Zn-coordinating DNA-binding domain
    In: Febs Letters 528 (2002), S. 95-100
    ISSN: 0014-5793
    DOI: 10.1016/S0014-5793(02)03257-X
  • Rehberg Stephan, Lischka Peter, Glaser Gabriele, Stamminger Thomas, Wegner Michael, Rosorius Olaf:
    Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation
    In: Molecular and Cellular Biology 22 (2002), S. 5826-5834
    ISSN: 0270-7306
    DOI: 10.1128/MCB.22.16.5826-5834.2002
  • Stolt Claus, Rehberg Stephan, Ader Marius, Lommes Petra, Riethmacher Dieter, Schachner Melitta, Bartsch Udo, Wegner Michael:
    Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10
    In: Genes & Development 16 (2002), S. 165-170
    ISSN: 0890-9369
    DOI: 10.1101/gad.215802

  • Sock Elisabeth, Schmidt Katy, Hermanns-Borgmeyer Irm, Bösl Michael, Wegner Michael:
    Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8
    In: Molecular and Cellular Biology 21 (2001), S. 6951-6959
    ISSN: 0270-7306
    DOI: 10.1128/MCB.21.20.6951-6959.2001
  • Wegner Michael, Riethmacher Dieter:
    Chronicles of a switch hunt: gcm genes in development
    In: Trends in Genetics 17 (2001), S. 286-90
    ISSN: 0168-9525
    DOI: 10.1016/S0168-9525(01)02275-2
  • Wegner M.:
    Expression of transcription factors during oligodendroglial development
    In: Microscopy Research and Technique 52 (2001), S. 746-752
    ISSN: 1059-910X
    DOI: 10.1002/jemt.1059
  • Paratore Christian, Goerich Derk E., Suter Ueli, Wegner Michael, Sommer Lukas:
    Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling
    In: Development 128 (2001), S. 3949-3961
    ISSN: 1477-9129
  • Britsch Stefan, Goerich Derk, Riethmacher Dieter, Peirano Reto, Rossner Moritz, Nave Klaus-Armin, Birchmeier Carmen, Wegner Michael:
    The transcription factor Sox10 is a key regulator of peripheral glial development
    In: Genes & Development 15 (2001), S. 66-78
    ISSN: 0890-9369
    DOI: 10.1101/gad.186601
  • Sonnenberg-Riethmacher Eva, Miehe Michaela, Stolt Claus, Goerich Derk, Wegner Michael, Riethmacher Dieter:
    Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10
    In: Mechanisms of Development 109 (2001), S. 253-265
    ISSN: 0925-4773
    DOI: 10.1016/S0925-4773(01)00547-0

  • Bondurand Nadège, Pingault Véronique, Goerich Derk, Lemort Nicole, Sock Elisabeth, Le Caignec Cedric, Wegner Michael, Goossens Michel:
    Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome
    In: Human Molecular Genetics 9 (2000), S. 1907-1917
    ISSN: 0964-6906
  • Baumeister Hans, Wegner Michael, Richter Dietmar, Meyerhof Wolfgang:
    Dual regulation of somatostatin receptor subtype 1 gene expression by pit-1 in anterior pipuitary GH3 cells
    In: Molecular Endocrinology 14 (2000), S. 255-71
    ISSN: 0888-8809
  • Winklhofer Konstanze, Albrecht Ingrid, Wegner Michael, Heilbronn Regine:
    Human cytomegalovirus immediate-early gene 2 expression leads to JCV replication in nonpermissive cells via transcriptional activation of JCV T antigen
    In: Virology 275 (2000), S. 323-334
    ISSN: 0042-6822
    DOI: 10.1006/viro.2000.0503
  • Schreiber Jörg, Riethmacher-Sonnenberg Eva, Riethmacher Dieter, Tuerk Elisabeth, Enderich Janna, Bösl Michael, Wegner Michael:
    Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa
    In: Molecular and Cellular Biology 20 (2000), S. 2466-2474
    ISSN: 0270-7306
    DOI: 10.1128/MCB.20.7.2466-2474.2000
  • Tuerk Elisabeth, Schreiber Jörg, Wegner Michael:
    Protein stability and domain topology determine the transcriptional activity of the mammalian glial cells missing homolog, GCMb
    In: Journal of Biological Chemistry 275 (2000), S. 4774-82
    ISSN: 0021-9258
    DOI: 10.1074/jbc.275.7.4774
  • Peirano Reto, Goerich Derk, Riethmacher Dieter, Wegner Michael:
    Protein zero Gene expression is regulated by the glial transcription factor Sox10
    In: Molecular and Cellular Biology 20 (2000), S. 3198-3209
    ISSN: 0270-7306
    DOI: 10.1128/MCB.20.9.3198-3209.2000
  • Peirano Reto, Wegner Michael:
    The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences
    In: Nucleic Acids Research 28 (2000), S. 3047-3055
    ISSN: 0305-1048
  • Wegner M.:
    Transcriptional control in myelinating glia: flavors and spices
    In: Glia 31 (2000), S. 1-14
    ISSN: 0894-1491
    DOI: 10.1002/(SICI)1098-1136(200007)31:13.0.CO;2-V
  • Wegner M.:
    Transcriptional control in myelinating glia: the basic recipe
    In: Glia 29 (2000), S. 118-23
    ISSN: 0894-1491
    DOI: 10.1002/(SICI)1098-1136(20000115)29:23.0.CO;2-Q

  • Sock Elisabeth, Enderich Janna, Wegner Michael:
    The J domain of papovaviral large tumor antigen is required for synergistic interaction with the POU-domain protein Tst-1/Oct6/SCIP
    In: Molecular and Cellular Biology 19 (1999), S. 2455-2464
    ISSN: 0270-7306
  • Vollgraf Ulrich, Wegner Michael, Richter-Landsberg Christiane:
    Activation of AP-1 and NF-kappa B transcription factors is involved in hydrogen peroxide-induced apoptopic cell death of oligodendrocytes
    In: Journal of Neurochemistry 73 (1999), S. 2501-2509
    ISSN: 0022-3042
  • Bondurand Nadége, Kuhlbrodt Kirsten, Pingault Véronique, Enderich Janna, Sajus Marc, Tommerup Niels, Warburg Mette, Hennekam Raoul, Read Andrew, Wegner Michael, Goossens Michel:
    A molecular analysis of the Yemenite deaf-blind hypopigmentation syndrome: Sox10 dysfunction causes different neurocristopathies
    In: Human Molecular Genetics 8 (1999), S. 1785-1789
    ISSN: 0964-6906
    DOI: 10.1093/hmg/8.9.1785
  • Schneider Carolin, Wicht Helmut, Enderich Janna, Wegner Michael, Rohrer Hermann:
    Bone morphogenetic proteins are required in vivo for the generation of sympathetic neurons
    In: Neuron 24 (1999), S. 861-870
    ISSN: 0896-6273
  • Wegner M.:
    From head to toes: the multiple facets of Sox proteins
    In: Nucleic Acids Research 27 (1999), S. 1409-1420
    ISSN: 0305-1048
    DOI: 10.1093/nar/27.6.1409
  • Reifegerst Rita, Schreiber Jörg, Gülland Sven, Lüdemann Anja, Wegner Michael:
    mGCMa is a murine transcription factor that overrides cell fate decisions in Drosophila
    In: Mechanisms of Development 82 (1999), S. 141-150
    ISSN: 0925-4773
    DOI: 10.1016/S0925-4773(99)00027-1

  • Kuhlbrodt Kirsten, Herbarth Beate, Sock Elisabeth, Enderich Janna, Hermans-Borgmeyer Irm, Wegner Michael:
    Cooperative function of POU proteins and SOX proteins in glial cells
    In: Journal of Biological Chemistry 273 (1998), S. 16050-16057
    ISSN: 0021-9258
    DOI: 10.1074/jbc.273.26.16050
  • Kuhlbrodt Kirsten, Schmidt Claudia, Sock Elisabeth, Pingault Veronique, Bondurand Nadege, Goossens Michel, Wegner Michael:
    Functional analysis of Sox10 mutations found in human Waardenburg-Hirschsprung patients
    In: Journal of Biological Chemistry 273 (1998), S. 23033-23038
    ISSN: 0021-9258
    DOI: 10.1074/jbc.273.36.23033
  • Kuhlbrodt Kirsten, Herbarth Beate, Sock Elisabeth, Hermans-Borgmeyer Irm, Wegner Michael:
    Sox10, a novel transcriptional modulator in glial cells
    In: Journal of Neuroscience 18 (1998), S. 237-250
    ISSN: 0270-6474
  • Herbarth Beate, Meissner Hildegard, Westphal Manfred, Wegner Michael:
    Absence of polyomavirus JC in glial brain tumors and glioma-derived cell lines
    In: Glia 22 (1998), S. 415-420
    ISSN: 0894-1491
    DOI: 10.1002/(SICI)1098-1136(199804)22:43.0.CO;2-Z
  • Staib Caroline, Wegner Michael, Grummt Friedrich:
    Activation of SV40 DNA replication in vivo by amplification-promoting sequences of the mouse ribosomal gene cluster
    In: Chromosoma 107 (1998), S. 33-38
    ISSN: 0009-5915
  • Bondurand Nadege, Kobetz Alexandra, Pingault Veronique, Lemort Nicole, Encha-Razavi Ferechte, Couly Gerard, Goerich Derk, Wegner Michael, Abitbol Marc, Goossens Michel:
    Expression of Sox10 gene during human development
    In: Febs Letters 432 (1998), S. 168-172
    ISSN: 0014-5793
    DOI: 10.1016/S0014-5793(98)00843-6
  • von der Kammer Heinz, Mayhaus Manuel, Albrecht Claudia, Enderich Janna, Wegner Michael, Nitsch Roger:
    Muscarinic acetylcholine receptors activate expression of the EGr gene family of transcription factors
    In: Journal of Biological Chemistry 273 (1998), S. 14538-14544
    ISSN: 0021-9258
    DOI: 10.1074/jbc.273.23.14538
  • Nitsch Roger, Rossner Stefan, Albrecht Claudia, Mayhaus Manuel, Enderich Janna, Schliebs Reinhard, Wegner Michael, Arendt Thomas, von der Kammer Heinz:
    Muscarinic acetylcholine receptors activate the acetylcholinesterase gene promoter
    In: Journal of Physiology-Paris 92 (1998), S. 257-264
    ISSN: 0928-4257
    DOI: 10.1016/S0928-4257(98)80029-6
  • Herbarth Beate, Pingault Veronique, Bondurand Nadege, Kuhlbrodt Kirsten, Hermans-Borgmeyer Irm, Puliti Aldamaria, Lemort Nicole, Goossens Michel, Wegner Michael:
    Mutation of the Sry-related Sox10 gene in Dominat megacolon, a mouse model for human Hirschsprung disease
    In: Proceedings of the National Academy of Sciences of the United States of America 95 (1998), S. 5161-5165
    ISSN: 0027-8424
  • Pingault Véronique, Bondurand Nadège, Kuhlbrodt Kirsten, Goerich Derk E., Préhu Marie-Odette, Puliti Aldamaria, Herbarth Beate, Hermans-Borgmeyer Irm, Legius Eric, Matthijs Gert, Amiel Jeanne, Lyonnet Stanislas, Ceccherini Isabella, Romeo Giovanni, Smith Jill Clayton, Read Andrew P., Wegner Michael, Goossens Michel:
    SOX10 mutations in patients with Waardenburg-Hirschsprung disease
    In: Nature Genetics 18 (1998), S. 171-173
    ISSN: 1061-4036
    DOI: 10.1038/ng0298-171
  • Schreiber Jörg, Enderich Janna, Wegner Michael:
    Structural requirements for DNA binding of GCM proteins
    In: Nucleic Acids Research 26 (1998), S. 2337-2343
    ISSN: 0305-1048
    DOI: 10.1093/nar/26.10.2337
Universität Erlangen-Nürnberg
Institut für Biochemie

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