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Publikationen AG Lie


Gebara E, Bonaguidi MA, Beckervordersandforth R, Sultan S, Udry F, Gijs PJ, Lie DC, Ming GL, Song H, Toni N
Heterogeneity of Radial Glia-Like Cells in the Adult Hippocampus.
Stem Cells. 2016;34(4): 997-1010


Cernilogar FM, Di Giaimo R, Rehfeld F, Cappello S, Lie DC
RNA interference machinery-mediated gene regulation in mouse adult neural stem cells.
BMC Neurosci. 2015;16: 60

Beckervordersandforth R, Zhang CL, Lie DC
Transcription-Factor-Dependent Control of Adult Hippocampal Neurogenesis.
Cold Spring Harb Perspect Biol. 2015;7(10)

Marschallinger J, Schäffner I, Klein B, Gelfert R, Rivera FJ, Illes S, Grassner L, Janssen M, Rotheneichner P, Schmuckermair C, Coras R, Boccazzi M, Chishty M, Lagler FB, Renic M, Bauer HC, Singewald N, Blümcke I, Bogdahn U, Couillard-Despres S, Lie DC, Abbracchio MP, Aigner L
Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
Nat Commun. 2015;6: 8466

Andreu Z, Khan MA, González-Gómez P, Negueruela S, Hortigüela R, San Emeterio J, Ferrón SR, Martínez G, Vidal A, Fariñas I, Lie DC, Mira H
The cyclin-dependent kinase inhibitor p27 kip1 regulates radial stem cell quiescence and neurogenesis in the adult hippocampus.
Stem Cells. 2015;33(1): 219-29


Steib K, Schäffner I, Jagasia R, Ebert B, Lie DC
Mitochondria modify exercise-induced development of stem cell-derived neurons in the adult brain.
J Neurosci. 2014;34(19): 6624-33

Karow M, Schichor C, Beckervordersandforth R, Berninger B
Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons.
J Vis Exp. 2014;(87)

Beckervordersandforth R, Deshpande A, Schäffner I, Huttner HB, Lepier A, Lie DC, Götz M
In vivo targeting of adult neural stem cells in the dentate gyrus by a split-cre approach.
Stem Cell Reports. 2014;2(2): 153-62


Ninkovic J, Steiner-Mezzadri A, Jawerka M, Akinci U, Masserdotti G, Petricca S, Fischer J, von Holst A, Beckers J, Lie CD, Petrik D, Miller E, Tang J, Wu J, Lefebvre V, Demmers J, Eisch A, Metzger D, Crabtree G, Irmler M, Poot R, Götz M
The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.
Cell Stem Cell. 2013;13(4): 403-18

Ortega F, Gascon S, Masserdotti G, Deshpande A, Simon C, Fischer J, Dimou L, Lie DC, Schroeder T, Berninger B
Glia. 2013;61 1: S153-S154

Sun M, Hölter SM, Stepan J, Garrett L, Genius J, Kremmer E, Hrab? de Angelis M, Wurst W, Lie DC, Bally-Cuif L, Eder M, Rujescu D, Graw J
Crybb2 coding for ?B2-crystallin affects sensorimotor gating and hippocampal function.
Mamm Genome. 2013;24(9-10): 333-48

Ortega F, Gascón S, Masserdotti G, Deshpande A, Simon C, Fischer J, Dimou L, Chichung Lie D, Schroeder T, Berninger B
Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling.
Nat Cell Biol. 2013;15(6): 602-13

Dimidschstein J, Passante L, Dufour A, van den Ameele J, Tiberi L, Hrechdakian T, Adams R, Klein R, Lie DC, Jossin Y, Vanderhaeghen P
Ephrin-B1 controls the columnar distribution of cortical pyramidal neurons by restricting their tangential migration.
Neuron. 2013;79(6): 1123-35

Merz K, Lie DC
Evidence that Doublecortin is dispensable for the development of adult born neurons in mice.
PLoS ONE. 2013;8(5): e62693


Karow M, Sánchez R, Schichor C, Masserdotti G, Ortega F, Heinrich C, Gascón S, Khan MA, Lie DC, Dellavalle A, Cossu G, Goldbrunner R, Götz M, Berninger B
Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells.
Cell Stem Cell. 2012;11(4): 471-6

Schwarz TJ, Ebert B, Lie DC
Stem cell maintenance in the adult mammalian hippocampus: a matter of signal integration?
Dev Neurobiol. 2012;72(7): 1006-15

Sanchez R, Karow M, Schichor C, Masserdotti G, Ortega F, Heinrich C, Gascon S, Khan MA, Lie DC, Dellavalle A, Cossu G, Goldbrunner R, Gotz M, Berninger B
Direct conversion of pericyte-derived cells of the adult human brain into functional neurons
Int J Dev Neurosci. 2012;30(8): 631-631

Mu L, Berti L, Masserdotti G, Covic M, Michaelidis TM, Doberauer K, Merz K, Rehfeld F, Haslinger A, Wegner M, Sock E, Lefebvre V, Couillard-Despres S, Aigner L, Berninger B, Lie DC
SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.
J Neurosci. 2012;32(9): 3067-80

Niv F, Keiner S, Krishna -, Witte OW, Lie DC, Redecker C
Aberrant neurogenesis after stroke: a retroviral cell labeling study.
Stroke. 2012;43(9): 2468-75


Khan MA, Lie DC
MicroRNA – a contributor to age-associated neural stem cell dysfunction?
Aging (Albany NY). 2011;3(3): 182-3

Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL
Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice.
Brain. 2011;134(Pt 7): 2044-56

Merz K, Herold S, Lie DC
CREB in adult neurogenesis–master and partner in the development of adult-born neurons?
Eur J Neurosci. 2011;33(6): 1078-86

Herold S, Jagasia R, Merz K, Wassmer K, Lie DC
CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis.
Mol Cell Neurosci. 2011;46(1): 79-88

Karalay O, Doberauer K, Vadodaria KC, Knobloch M, Berti L, Miquelajauregui A, Schwark M, Jagasia R, Taketo MM, Tarabykin V, Lie DC, Jessberger S
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis.
Proc Natl Acad Sci U S A. 2011;108(14): 5807-12


Mira H, Andreu Z, Suh H, Lie DC, Jessberger S, Consiglio A, San Emeterio J, Hortigüela R, Marqués-Torrejón MA, Nakashima K, Colak D, Götz M, Fariñas I, Gage FH
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.
Cell Stem Cell. 2010;7(1): 78-89

Beckervordersandforth R, Tripathi P, Ninkovic J, Bayam E, Lepier A, Stempfhuber B, Kirchhoff F, Hirrlinger J, Haslinger A, Lie DC, Beckers J, Yoder B, Irmler M, Götz M
In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells.
Cell Stem Cell. 2010;7(6): 744-58

Covic M, Karaca E, Lie DC
Epigenetic regulation of neurogenesis in the adult hippocampus.
Heredity (Edinb). 2010;105(1): 122-34

Ehm O, Göritz C, Covic M, Schäffner I, Schwarz TJ, Karaca E, Kempkes B, Kremmer E, Pfrieger FW, Espinosa L, Bigas A, Giachino C, Taylor V, Frisén J, Lie DC
RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.
J Neurosci. 2010;30(41): 13794-807


Haslinger A, Schwarz TJ, Covic M, Lie DC
Expression of Sox11 in adult neurogenic niches suggests a stage-specific role in adult neurogenesis.
Eur J Neurosci. 2009;29(11): 2103-14

Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, Saxe M, Gage FH, Song H, Lie DC
GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.
J Neurosci. 2009;29(25): 7966-77

Jessberger S, Clark RE, Broadbent NJ, Clemenson GD, Consiglio A, Lie DC, Squire LR, Gage FH
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats.
Learn Mem. 2009;16(2): 147-54

Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.
Nat Neurosci. 2009;12(9): 1097-105


Michaelidis TM, Lie DC
Wnt signaling and neural stem cells: caught in the Wnt web.
Cell Tissue Res. 2008;331(1): 193-210

Winner B, Rockenstein E, Lie DC, Aigner R, Mante M, Bogdahn U, Couillard-Despres S, Masliah E, Winkler J
Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.
Neurobiol Aging. 2008;29(6): 913-25

Jessberger S, Aigner S, Clemenson GD, Toni N, Lie DC, Karalay O, Overall R, Kempermann G, Gage FH
Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus.
PLoS Biol. 2008;6(11): e272


Winner B, Lie DCC, Rockenstein ER, Masliah E, Bogdahn U, Winkler J
Impaired adult neurogenesis: Potential mechanisms involved in olfactory impairment in PD
Neurology. 2006;66 2(5): A125-A125

Jacobs S, Lie DC, DeCicco KL, Shi Y, DeLuca LM, Gage FH, Evans RM
Retinoic acid is required early during adult neurogenesis in the dentate gyrus.
Proc Natl Acad Sci U S A. 2006;103(10): 3902-7

Jagasia R, Song H, Gage FH, Lie DC
New regulators in adult neurogenesis and their potential role for repair.
Trends Mol Med. 2006;12(9): 400-5


Lie DC, Colamarino SA, Song HJ, Désiré L, Mira H, Consiglio A, Lein ES, Jessberger S, Lansford H, Dearie AR, Gage FH
Wnt signalling regulates adult hippocampal neurogenesis.
Nature. 2005;437(7063): 1370-5


Winner B, Lie DC, Rockenstein E, Aigner R, Aigner L, Masliah E, Kuhn HG, Winkler J
Human wild-type alpha-synuclein impairs neurogenesis.
J Neuropathol Exp Neurol. 2004;63(11): 1155-66

Wurmser AE, Nakashima K, Summers RG, Toni N, D’Amour KA, Lie DC, Gage FH
Cell fusion-independent differentiation of neural stem cells to the endothelial lineage.
Nature. 2004;430(6997): 350-6

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