Publikationen

Zhang I., Boezio GL., Cornwall-Scoones J., Frith T., Finnie E., Luo J., Jiang M., Howell M., Lovell-Badge R., Sagner A., Briscoe J., Delás MJ.:
The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
In: Developmental Cell (2025)
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2025.06.029

Sagner A.:
Temporal patterning of the vertebrate developing neural tube
In: Current Opinion in Genetics & Development 86 (2024), Article No.: 102179
ISSN: 0959-437X
DOI: 10.1016/j.gde.2024.102179

Karpf J., Unichenko P., Chalmers N., Beyer F., Wittmann MT., Schneider J., Fidan E., Reis A., Beckervordersandforth J., Brandner S., Liebner S., Falk S., Sagner A., Henneberger C., Beckervordersandforth R.:
Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features
In: Nature Neuroscience 25 (2022), p. 1626-1638
ISSN: 1097-6256
DOI: 10.1038/s41593-022-01192-5

Exelby K., Herrera-Delgado E., Perez LG., Perez-Carrasco R., Sagner A., Metzis V., Sollich P., Briscoe J.:
Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks
In: Development 148 (2021), Article No.: dev197566
ISSN: 1477-9129
DOI: 10.1242/dev.197566
Sagner A., Zhang I., Watson T., Lazaro J., Melchionda M., Briscoe J.:
A shared transcriptional code orchestrates temporal patterning of the central nervous system
In: Plos Biology 19 (2021), Article No.: e3001450
ISSN: 1544-9173
DOI: 10.1371/journal.pbio.3001450

Delile J., Rayon T., Melchionda M., Edwards A., Briscoe J., Sagner A.:
Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord
In: Development 146 (2019), Article No.: dev173807
ISSN: 1477-9129
DOI: 10.1242/dev.173807
Sagner A., Briscoe J.:
Establishing neuronal diversity in the spinal cord: A time and a place
In: Development 146 (2019), Article No.: dev182154
ISSN: 1477-9129
DOI: 10.1242/dev.182154

Pusapati GV., Kong JH., Patel BB., Gouti M., Sagner A., Sircar R., Luchetti G., Ingham PW., Briscoe J., Rohatgi R.:
G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog
In: Science Signaling 11 (2018)
ISSN: 1937-9145
DOI: 10.1126/scisignal.aao5749
Pusapati GV., Kong JH., Patel BB., Krishnan A., Sagner A., Kinnebrew M., Briscoe J., Aravind L., Rohatgi R.:
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog
In: Developmental Cell 44 (2018), p. 113-129.e8
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2017.12.003
Sagner A., Gaber ZB., Delile J., Kong JH., Rousso DL., Pearson CA., Weicksel SE., Melchionda M., Gharavy SNM., Briscoe J., Novitch BG.:
Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics
In: Plos Biology 16 (2018), Article No.: e2003127
ISSN: 1544-9173
DOI: 10.1371/journal.pbio.2003127

Blasse C., Saalfeld S., Etournay R., Sagner A., Eaton S., Myers EW.:
PreMosa: extracting 2D surfaces from 3D microscopy mosaics
In: Bioinformatics 33 (2017), p. 2563-2569
ISSN: 1367-4803
DOI: 10.1093/bioinformatics/btx195
Sagner A., Aigouy B., Collinet C., Merkel M., Sagner A.:
Quantitative methods to study epithelial morphogenesis and polarity
In: Methods in Cell Biology 139 (2017), p. 121-152
ISSN: 0091-679X
DOI: 10.1016/bs.mcb.2016.12.004
Sagner A., Briscoe J.:
Morphogen interpretation: concentration, time, competence, and signaling dynamics
In: Wiley Interdisciplinary Reviews: Developmental Biology 6 (2017), Article No.: e271
ISSN: 1759-7684
DOI: 10.1002/wdev.271

Luchetti G., Sircar R., Kong JH., Nachtergaele S., Sagner A., Byrne EFX., Covey DF., Siebold C., Rohatgi R.:
Cholesterol activates the G-protein coupled receptor smoothened to promote hedgehog signaling
In: eLife 5 (2016), Article No.: e20304
ISSN: 2050-084X
DOI: 10.7554/eLife.20304

Cho B., Pierre-Louis G., Sagner A., Eaton S., Axelrod JD.:
Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle
In: PLoS Genetics 11 (2015), Article No.: e1005259
ISSN: 1553-7390
DOI: 10.1371/journal.pgen.1005259
Dunst S., Kazimiers T., Von Zadow F., Jambor H., Sagner A., Brankatschk B., Mahmoud A., Spannl S., Tomancak P., Eaton S., Brankatschk M.:
Endogenously Tagged Rab Proteins: A Resource to Study Membrane Trafficking in Drosophila
In: Developmental Cell 33 (2015), p. 351-365
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2015.03.022

Merkel M., Sagner A., Gruber FS., Etournay R., Blasse C., Myers E., Eaton S., Juelicher F.:
The balance of prickle/spiny-legs isoforms controls the amount of coupling between core and fat PCP systems
In: Current Biology 24 (2014), p. 2111-2123
ISSN: 0960-9822
DOI: 10.1016/j.cub.2014.08.005

Sagner A., Merkel M., Aigouy B., Gaebel J., Brankatschk M., Juelicher F., Eaton S.:
Establishment of global patterns of planar polarity during growth of the drosophila wing epithelium
In: Current Biology 22 (2012), p. 1296-1301
ISSN: 0960-9822
DOI: 10.1016/j.cub.2012.04.066

Aigouy B., Etournay R., Sagner A., Staple DB., Farhadifar R., Roper JC., Eaton S., Julicher F.:
Cell flow reorients planar polarity in the wing of Drosophila Caresser la polarité planaire dans le sens du flot
In: M S-Medecine Sciences 27 (2011), p. 117-119
ISSN: 0767-0974
DOI: 10.1051/medsci/2011272117

Aigouy B., Staple DB., Farhadifar R., Sagner A., Roeper JC., Juelicher F., Eaton S.:
Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila
In: Cell 142 (2010), p. 773-786
ISSN: 0092-8674
DOI: 10.1016/j.cell.2010.07.042

2025